| Entrez gene ID | | 13609 |
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| Official gene symbol | | S1pr1 |
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| Full name | | sphingosine-1-phosphate receptor 1 |
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| Aliases | | AI849002,Edg1,Lpb1,S1p,S1p1 |
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| Gene summary | | This gene encodes a G-protein-coupled receptor bound by the lysophospholipid, sphingosine 1-phosphate. The gene product functions in endothelial cells and is involved in vascular and heart development. This receptor is highly expressed in T and B lymphocytes, and it plays a role in T cell and B cell export from peripheral lymphoid organs. This protein is bound and downregulated by FTY720, an exogenous immunosuppressant drug studied in mouse disease models for multiple sclerosis in humans. [provided by RefSeq] |
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| Location | | Chromosome: 3 Locus: 3 G1 |
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| Gene position | | 115417973 - 115413351 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 4623 bp |
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| Gene sequence |
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