Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for STXBP5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID134957
Official gene symbolSTXBP5
Full namesyntaxin binding protein 5 (tomosyn)
Aliases,FLJ30922,LGL3,LLGL3,MGC141942,MGC141968,Nbla04300,
Gene summarySyntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q24.3
Gene position147525508 - 147708707  Map Viewer
Gene orientationplus
Gene size183200 bp
Gene sequence
OMIM ID604586