| Entrez gene ID | | 1314 |
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| Official gene symbol | | COPA |
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| Full name | | coatomer protein complex, subunit alpha |
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| Aliases | | ,FLJ26320,HEP-COP, |
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| Gene summary | | In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. [provided by RefSeq] |
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| Location | | Chromosome: 1 Locus: 1q23-q25 |
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| Gene position | | 160313354 - 160258377 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 54978 bp |
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| Gene sequence |
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| OMIM ID | | 601924 |
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