| Entrez gene ID | | 12964 |
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| Official gene symbol | | Cryga |
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| Full name | | crystallin, gamma A |
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| Aliases | | Cryg-4,DGcry-4 |
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| Gene summary | | Three main families of major soluble proteins, the alpha, beta and gamma crystallins, are ubiquitously expressed in vertebrate lenses. This gene encodes a member of the gamma-crystallin family of proteins which may function as a structural component of the eye lens. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Five gamma-crystallin genes (gamma-A through gamma-E) are tandemly organized in a genomic segment as a gene cluster in the mouse. Another gamma-crystallin gene (gamma-F) is found some distance upstream of the cluster on the same chromosome. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq] |
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| Location | | Chromosome: 1 Locus: 1 C2|1 32.0 cM |
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| Gene position | | 65149937 - 65146963 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 2975 bp |
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| Gene sequence |
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