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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for Cftr (Mus musculus)
(Information is obtained from NCBI Gene database)
Entrez gene ID12638
Official gene symbolCftr
Full namecystic fibrosis transmembrane conductance regulator homolog
AliasesAW495489,Abcc7
Gene summaryThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This gene encodes the cystic fibrosis transmembrane regulator and a chloride channel that controls the regulation of other transport pathways. Mutations in this gene have been associated with autosomal recessive disorders such as cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternative splicing of exons 4, 5, and 11 have been observed, but full-length transcripts have not yet been fully described. [provided by RefSeq]
LocationChromosome: 6   Locus: 6 3.1 cM
Gene position18120687 - 18272770  Map Viewer
Gene orientationplus
Gene size152084 bp
Gene sequence