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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CCR1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1230 Official gene symbol CCR1 Full name chemokine (C-C motif) receptor 1 Aliases ,CD191,CKR-1,CKR1,CMKBR1,HM145,MIP1aR,SCYAR1, Gene summary This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq] Location Chromosome: 3   Locus: 3p21 Gene position 46249832 - 46243200  Map Viewer Gene orientation minus Gene size 6633 bp Gene sequence >CCR1:complement(46183200..46189832):Length=6633 ATAAAAACCCAGAAAGCCCCAGAAACAAAGACTTCACGGACAAAGTCCCTTGGAACCAGA GTAAGTGTCACTTGTCTTTTCTGTCTTATCTGTTACTGTGGAGGGCAGTGTTGTTCAAAG ACATGCATGCAGCTAGGGGCTCCTCAAAGGTAGGGGGAATTCTTTGAGTAGGCTGGGCAA ATGTCTAAGTAGCCCATGGATGCATCTCCAAGGCAATTAATACTGTAGCAATACTGAGAA TGGTGGATTTATAAAGCTGGGTGCTCAGATGAAATATAGGCTTTTTTGCTAAAAAGGAAG CTTACTTGAAGGATTGGCTTTTGGTTACTGATTAAGAAAGTCAGTCAGTACTAAGGGACA AAAGGTGTTTTCTGTGGAAACCTATTCAATAAGAAATTACTTGGCGGGGCGCAGTGGCTC ACGGCTGTAATCCCAGCACTTTGGGAGACCGAGGCAGGTGGATCATGAGGTCAAGAGATG GAGACAATCCTGGCCATATGGTGAAACCCTGTCTCTACTAAAAATAAAAATTAGCCGGGC ATGGTGGCGCATGCCTGTAGTCCCAGCTACTCAAGAGGCTGAGGCAGGAGAATCACTCGA ATCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATTGCACCACTACACTCCAGCCTGGCGAC AGAGCAAGAGTCTGTCTGAAAAAAAAAAAAAAATTGCTTGCCAAATTCCCCCATGTAAAG GAAAACCAAACATGGTGTATGAAGAAATTATAGCAAGAGGGAAATATTAGCTAGAAAAAT CTTGGCAGATGCAAGGATGATTTGATACTGAACCTATCTCTTAAGAAGACTAGAACCAAG GATCCTCAAAATTGGCACTGCTATCTTTGGAAGAGGTAGGCTTTCACTCACCCAAAGGCA AGGAGCTGGCCAGGTGATCTTGGGGGGCATCTGTTCTGCTCTACTAACAAAGACACAGGT CAGGATTTTGTTCTGAAGATAGAGGGGCATGGTGGCTCCGTATAGGTATCTACTTCATAG GTGGTCTTGGTGGGTCCCAGATTTCAAAGAAGAGATGGAAACTCCCAAAAGTTTGCACAA CCTGGCACCAGGCTATGTGCCACTCACTGATCCTTTAGTTCCCGCACCGAGCAGTGGGAC AGTGCTGGACTGTTCAGAATGTGGGGCCTGGGCAGTGATGTGCTGGTAAATGTTCAACAA CTGACTCTTCTGAAGAAAAGATCCCTGCTTTATAACATTTGTTGATTTTCATGGTATAAA TGCCCCCACTGTGGTCAGTTTCAAGCTACCAACATGCTGAATGTGGAGTGGGGAAGAGAT GCACGCAATTGGCATTTATAAACCAGTATAAGCCAGCCAGCGCACCATAGGCCTGGGTGT CTTTCACCATCACAGACTGCTCTATCTCTGCTCAGAGACTTCACCAACTCCCAGGCTGGA GGACACTAGCAGTGGAGGGTCCAGGATCCAGGGCTATAGCTGACCACTGTGCAGTGGCCT TGAGGCAGACTTCTGCAGTAGACTACAGCAGGGCTGGCAGATTAGATGACAACATGGTCC TTTGGTTTCTCTTCTCGGGCCCCACCCCAGATCACCTCCCTTTAGGAACAGCATGCCTTG GAGTGGTTGCCTGGGGCTTAACAAGTTGGGGAAATAACAAATGGGTTGGAGGTAGGGGGT GTATGGAGGTGACTCGGTTTAAAATGCCACCTGACAATGTTGACTCAACTTGCCTTTGCC TTTGCCAAACCTTCCCAGAAACTGGACTCATGGGATCAGGCTTGCACTAGCTGCTCTTTG TGCTTTCCAAGCTATTTGCATACTTCCACTGTTAACCTGCCAGCCCACCGAAAAGTGCTG ACTATCAAACCGAACTGTCTGCCCTCATCAGCAATGGCTGTGGCTGCAGAAATTAGAAAC TGCCAACACAGCTTTGTTAGTGACCGTTAGCCTGACTCTCTCCAGAAAGAGGGCTGATTG GATCTCTCTGGAGATGGAGGAGTGGGCCAGGGGATGGGTTTGATAAAAAATTAAAGCTCC TCACTTCTCACCCTAATAGAGTATCTCCCTTTCCAGCCAGGGTGCCCTATACCCTCCATG TGCCTTAATTTCCTTTACAATGGCTATTGAAAAAAATGTGAATTGTGTAAGCAGGAAACA TTCCTTAAGGAGAGTAGAAGGAAGAACACCAGAGACCCAGGTTTAAGATAGAAATTATAA AGTAGGTGCCACCTACTTTACTGATTGGCATTTGGGTCAAATCAATTTAGATTGGCGGCA ATAGATTGACAATTTCAAATGTCATTCACATGGAAGGGACCATCATTGTCCACCGTTATC AAGAAAAATCACTTTCTAGATTAACTACAAAGAAATTTGGCAGGGGGGTGGGAGACAGGG TATACCAGCCAGCCAGGGACATCCTGGACATTGGTGCCTGGGATGTGCTGGTGGTGTCAG GCCTCAGGGAAGGGCTCCTGCAGTGAAGGAGTTCTCTCAGGGAAGGTCCCCAAGAAAAGT GCCCTGGCCTGGCTCTTGCCAGGCCCTCAATAAGGGGCCTGGCTGTTGCCAGGTGGTGGT GGTGGGAGGGTGATGGTAGCACTTTTCTCATACATTACCTCACAGTAGCCTTGCAAGATA AGAGTTGCTTTCCCACATTACAGATGAGGAATGAAGCTCAGAGAGGTAAAATAATTTATC CAAAGTCACAAAGCTCGTAGGTTACACCAAAGCCAATGCTCCATTTGGGGAGGCATCTTT AATAAGCAACTGGAAAGGATTCAAGTGCCAAAAAAGCAGGGACTGGGAGAAGTCCTACAA AGGCAACCTACAGAGTGATTCTTTTTTGTTTCATTTTTGTTTGCTTTAAGGCATCCGTGG GTAAAAATATCTAAGAGCTTATCTCAGCAGAATTCAGCTAGTCACTGTGTAACATCACCT CATAGCTCCAGACCATTCTGAACTCTTCCTCCCCTGATGCCCAGTTTTCTCTTTTTCTGA CCAGGTTACCTCCCCCTTCTCTGCCTGCACTTTCCTCTCCTTCAGGAGGTCTGCAAAGTG ACCTTAGATCTACCTGTGCCACCTAAGGACTGTGCAATGTGGGTCAGGCTCAGCCCACTC TGGTGCCCTCAGTGTCCTCATCTCCAAAATAATGGGGTTGACCTACTAGGATTTCACTAT GGCAACACCACTGGTGTTTGGGGTAGAATGATCTCTGCACTGTAGGACATCCTTGGCCCT GCCTACCAAATGACGGTAGCATCCCCCAGTTTTGGTGACAACAACAACAAATGCCCACAC ATTTCCAAGTGCCCCAAGGGTACTAGGTCACTCTCGGCTGAGAATCTTCTTAGACCAAAA GCCATGAATATCTGTTTGTATCTTTCTCTGAGCCAGGACCATTTTCCTTCTCAGAGTCCT CCTGTGGGCTCCACAGTGCAAAGCTACTGCTCGGGGACAGCAGCAGGAAAGCGTAGTGGT GTCAGGGCCGGGCATGAGAATGATGCACAGCTGGGTTGGAGCTCCAGGTCTGTTCTCACA AGAGGTGTGTCCTTGAACATGTTTCCTAACCACTCTGAACCTCTGTTTCATCACCTCTTA AATAAGAACAACAATGGGACCCCTCCAGGGCTCTTTAACCCTAAGTCCAGTGCCTAGGCC ATGGGGGTGCTTAGGAAGTGTTGGTTATGAATAGTATGGTAAGGTCTCCCTCTGGCTTTC CACCCATTGAACTTATCCCTTACAAAACTCTTTGCTGAAATGATTGAATTAATGATTTGT GCACTCATTTACTTATTGCTTCCACTCCCTGTTAGACTAAGATTCCTAGAAGGCAGAGAG GATCTGGGTCTCTCTAACACTCCATTTTGTCCCCAGGGCATGGTACACAGAAGGCACTCA ATAAACATTTATGGAGTGGCTGAAAAAATGTTACCTCTCCCTTGTCTTTACTGTCCAGTG CCCACTGCCTTTAGTAGCAGAGTAAAGACAAATCTTTTTTTTTTTTTTAACCTGTAGGAG AAGCCGGGATGGAAACTCCAAACACCACAGAGGACTATGACACGACCACAGAGTTTGACT ATGGGGATGCAACTCCGTGCCAGAAGGTGAACGAGAGGGCCTTTGGGGCCCAACTGCTGC CCCCTCTGTACTCCTTGGTATTTGTCATTGGCCTGGTTGGAAACATCCTGGTGGTCCTGG TCCTTGTGCAATACAAGAGGCTAAAAAACATGACCAGCATCTACCTCCTGAACCTGGCCA TTTCTGACCTGCTCTTCCTGTTCACGCTTCCCTTCTGGATCGACTACAAGTTGAAGGATG ACTGGGTTTTTGGTGATGCCATGTGTAAGATCCTCTCTGGGTTTTATTACACAGGCTTGT ACAGCGAGATCTTTTTCATCATCCTGCTGACGATTGACAGGTACCTGGCCATCGTCCACG CCGTGTTTGCCTTGCGGGCACGGACCGTCACTTTTGGTGTCATCACCAGCATCATCATTT GGGCCCTGGCCATCTTGGCTTCCATGCCAGGCTTATACTTTTCCAAGACCCAATGGGAAT TCACTCACCACACCTGCAGCCTTCACTTTCCTCACGAAAGCCTACGAGAGTGGAAGCTGT TTCAGGCTCTGAAACTGAACCTCTTTGGGCTGGTATTGCCTTTGTTGGTCATGATCATCT GCTACACAGGGATTATAAAGATTCTGCTAAGACGACCAAATGAGAAGAAATCCAAAGCTG TCCGTTTGATTTTTGTCATCATGATCATCTTTTTTCTCTTTTGGACCCCCTACAATTTGA CTATACTTATTTCTGTTTTCCAAGACTTCCTGTTCACCCATGAGTGTGAGCAGAGCAGAC ATTTGGACCTGGCTGTGCAAGTGACGGAGGTGATCGCCTACACGCACTGCTGTGTCAACC CAGTGATCTACGCCTTCGTTGGTGAGAGGTTCCGGAAGTACCTGCGGCAGTTGTTCCACA GGCGTGTGGCTGTGCACCTGGTTAAATGGCTCCCCTTCCTCTCCGTGGACAGGCTGGAGA GGGTCAGCTCCACATCTCCCTCCACAGGGGAGCATGAACTCTCTGCTGGGTTCTGACTCA GACCATAGGAGGCCAACCCAAAATAAGCAGGCGTGACCTGCCAGGCACACTGAGCCAGCA GCCTGGCTCTCCCAGCCAGGTTCTGACTCTTGGCACAGCATGGAGTCACAGCCACTTGGG ATAGAGAGGGAATGTAATGGTGGCCTGGGGCTTCTGAGGCTTCTGGGGCTTCAGTCTTTT CCATGAACTTCTCCCCTGGTAGAAAGAAGATGAATGAGCAAAACCAAATATTCCAGAGAC TGGGACTAAGTGTACCAGAGAAGGGCTTGGACTCAAGCAAGATTTCAGATTTGTGACCAT TAGCATTTGTCAACAAAGTCACCCACTTCCCACTATTGCTTGCACAAACCAATTAAACCC AGTAGTGGTGACTGTGGGCTCCATTCAAAGTGAGCTCCTAAGCCATGGGAGACACTGATG TATGAGGAATTTCTGTTCTTCCATCACCTCCCCCCCCCCGCCACCCTCCCACTGCCAAAG AACTTGGAAATAGTGATTTCCACAGTGACTCCACTCTGAGTCCCAGAGCCAATCAGTAGC CAGCATCTGCCTCCCCTTCACTCCCACCGCAGGATTTGGGCTCTTGGAATCCTGGGGAAC ATAGAACTCATGACGGAAGAGTTGAGACCTAACGAGAAATAGAAATGGGGAACTACTGCT GGCAGTGGAACTAAGAAAGCCCTTAGGAAGAATTTTTATATCCACTAAAATCAAACAATT CAGGGAGTGGGCTAAGCACGGGCCATATGAATAACATGGTGTGCTTCTTAAAATAGCCAT AAAGGGGAGGGACTCATCATTTCCATTTACCCTTCTTTTCTGACTATTTTTCAGAATCTC TCTTCTTTTCAAGTTGGGTGATATGTTGGTAGATTCTAATGGCTTTATTGCAGCGATTAA TAACAGGCAAAAGGAAGCAGGGTTGGTTTCCCTTCTTTTTGTTCTTCATCTAAGCCTTCT GGTTTTATGGGTCAGAGTTCCGACTGCCATCTTGGACTTGTCAGCAAAAAAAAAAAATAA TAATAATAATAAGGCCTGCTGTGTAAGCTGACAGTATTTGTAGCTGATAGGGGGTTGGGA GGAAAGTGTCTACTAGGAGGGTGGGGTGAGATTCTGTGTTGATGTAGGAGGCCGAGAAGG CCCTTAACTCAAAGTAGCTTATTTATCCAAAATGTTCTGGATGCATCATCTCCAACCAAG GACCCCTTATTTATCATGCCTTTGTTCTCTTTTCCCTCAGATGTATATTTCTTTAAAAAT AATTTTCCTAATAACAAAACTTATTTCTAAAACAGCTTAAAAATTCAAAGAAAAACCCCA AACACTGACATTACCTACACTTCCACTACCCAAAGACAAAATGTGCCCACTGTGTGCTTT TGAGTGTATTTTCTTTTAGTTTGTTTTTTGTTGGGTGCATATTTATGATAATAACAATGA TGGACTTCAATTGTACTCACTGTTCTATTGTTGGTTTTAATTAGCAGCAAGTTGTGATCA CTTTCCCAGGTGAATAAATCATTTCAAAGCATT OMIM ID 601159