| Entrez gene ID | | 114908 |
| Official gene symbol | | TMEM123 |
| Full name | | transmembrane protein 123 |
| Aliases | | ,KCT3,PORIMIN,PORMIN, |
| Gene summary | | This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq] |
| Location | | Chromosome: 11 Locus: 11q22.1 |
| Gene position | | 102323775 - 102267056 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 56720 bp |
| Gene sequence |
| |
| OMIM ID | | 606356 |
|