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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CIDEA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1149
Official gene symbolCIDEA
Full namecell death-inducing DFFA-like effector a
Aliases,CIDE-A,
Gene summaryThis gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq]
LocationChromosome: 18   Locus: 18p11.21|18
Gene position12254318 - 12277594  Map Viewer
Gene orientationplus
Gene size23277 bp
Gene sequence
OMIM ID604440