Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PLCD3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID113026
Official gene symbolPLCD3
Full namephospholipase C, delta 3
Aliases,MGC71172,
Gene summaryThis gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q21.31
Gene position43209891 - 43189008  Map Viewer
Gene orientationminus
Gene size20884 bp
Gene sequence
OMIM ID608795