| Entrez gene ID | | 113026 |
| Official gene symbol | | PLCD3 |
| Full name | | phospholipase C, delta 3 |
| Aliases | | ,MGC71172, |
| Gene summary | | This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq] |
| Location | | Chromosome: 17 Locus: 17q21.31 |
| Gene position | | 43209891 - 43189008 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 20884 bp |
| Gene sequence |
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| OMIM ID | | 608795 |
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