| Entrez gene ID | | 11213 |
| Official gene symbol | | IRAK3 |
| Full name | | interleukin-1 receptor-associated kinase 3 |
| Aliases | | ,ASRT5,FLJ13601,IRAKM, |
| Gene summary | | This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq] |
| Location | | Chromosome: 12 Locus: 12q14.3 |
| Gene position | | 66582978 - 66648402 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 65425 bp |
| Gene sequence |
| |
| OMIM ID | | 604459 |
|