| Entrez gene ID | | 1118 |
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| Official gene symbol | | CHIT1 |
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| Full name | | chitinase 1 (chitotriosidase) |
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| Aliases | | ,CHI3,CHIT,FLJ00314,MGC125322, |
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| Gene summary | | Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. [provided by RefSeq] |
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| Location | | Chromosome: 1 Locus: 1q31-q32 |
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| Gene position | | 203198860 - 203185207 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 13654 bp |
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| Gene sequence |
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| OMIM ID | | 600031 |
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