| Entrez gene ID | | 11096 |
| Official gene symbol | | ADAMTS5 |
| Full name | | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| Aliases | | ,ADAMTS11,ADMP-2,FLJ36738, |
| Gene summary | | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage. [provided by RefSeq] |
| Location | | Chromosome: 21 Locus: 21q21.3 |
| Gene position | | 28339439 - 28290231 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 49209 bp |
| Gene sequence |
| |
| OMIM ID | | 605007 |
|