| Entrez gene ID | | 11078 |
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| Official gene symbol | | TRIOBP |
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| Full name | | TRIO and F-actin binding protein |
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| Aliases | | ,DFNB28,FLJ39315,HRIHFB2122,KIAA1662,TARA,dJ37E16.4, |
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| Gene summary | | This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq] |
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| Location | | Chromosome: 22 Locus: 22q13.1 |
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| Gene position | | 38092995 - 38172563 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 79569 bp |
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| Gene sequence |
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| OMIM ID | | 609761 |
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