| Entrez gene ID | | 11059 |
| Official gene symbol | | WWP1 |
| Full name | | WW domain containing E3 ubiquitin protein ligase 1 |
| Aliases | | ,AIP5,DKFZp434D2111,Tiul1,hSDRP1, |
| Gene summary | | WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq] |
| Location | | Chromosome: 8 Locus: 8q21 |
| Gene position | | 87354994 - 87480181 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 125188 bp |
| Gene sequence |
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| OMIM ID | | 602307 |
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