| Entrez gene ID | | 10873 |
| Official gene symbol | | ME3 |
| Full name | | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| Aliases | | ,FLJ34862, |
| Gene summary | | Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq] |
| Location | | Chromosome: 11 Locus: 11cen-q22.3 |
| Gene position | | 86383678 - 86152150 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 231529 bp |
| Gene sequence |
| |
| OMIM ID | | 604626 |
|