| Entrez gene ID | | 1073 |
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| Official gene symbol | | CFL2 |
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| Full name | | cofilin 2 (muscle) |
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| Aliases | | ,NEM7, |
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| Gene summary | | This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
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| Location | | Chromosome: 14 Locus: 14q12 |
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| Gene position | | 35184029 - 35179588 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 4442 bp |
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| Gene sequence |
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| OMIM ID | | 601443 |
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