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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for UBE2E3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10477
Official gene symbolUBE2E3
Full nameubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
Aliases,UBCH9,UbcM2,
Gene summaryThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q32.1
Gene position181845112 - 181928150  Map Viewer
Gene orientationplus
Gene size83039 bp
Gene sequence
OMIM ID604151