| Entrez gene ID | | 104709 |
|
| Official gene symbol | | Pik3r6 |
|
| Full name | | phosphoinositide-3-kinase, regulatory subunit 6 |
|
| Aliases | | BB220380,p84,p87(PIKAP),p87PIKAP |
|
| Gene summary | | Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 11. The protein binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
|
| Location | | Chromosome: 11 Locus: 11 B3 |
|
| Gene position | | 68316521 - 68366200 Map Viewer |
|
| Gene orientation | | plus |
|
| Gene size | | 49680 bp |
|
| Gene sequence |
| |
|
|
