| Entrez gene ID | | 1028 |
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| Official gene symbol | | CDKN1C |
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| Full name | | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
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| Aliases | | ,BWCR,BWS,KIP2,WBS,p57, |
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| Gene summary | | This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq] |
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| Location | | Chromosome: 11 Locus: 11p15.5 |
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| Gene position | | 2906995 - 2904448 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 2548 bp |
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| Gene sequence |
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| OMIM ID | | 600856 |
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