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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MSLN (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 10232 Official gene symbol MSLN Full name mesothelin Aliases ,MPF,SMRP, Gene summary This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants. Location Chromosome: 16   Locus: 16p13.3 Gene position 810765 - 818865  Map Viewer Gene orientation plus Gene size 8101 bp Gene sequence >MSLN:750765..758865:Length=8101 TGCCAGGCTCTCCACCCCCACTTCCCAATTGAGGAAACCGAGGCAGAGGAGGCTCAGGTG TGGCCAATCACCCTGCACATCAGAGTTACCCTGGGCAGGGCCCACTGAGACCTGGGAGGG GCCACTCGGGACCTGGAGGGCTGGGGGCTGCCCGGGCGTTAGGGGTAAAGCTCCCTACCC AACTGCGCAGAAGGCCTCAGAGGCCTGGGGGCTGGGCTTCCCCTTTCACATCGCCCTTTA GAGGCCCACGTGTGGGCATTGGCCCGCGATCTGAAAGGGGCTGTCCTGTTCCTCATGGGC GCTGCCAGCGCCACGCACTCCTCTTTCTGCCTGGCCGGCCACTCCCGTCTGCTGTGACGC GCGGACAGAGAGCTACCGGTGGACCCACGGTGCCTCCCTCCCTGGGATCTGTAAGTAACA ACCTTTGAGCTCTTCCTGTTGTGGTGTGGATGGAATCTGCACCTTCCATCTGGAGAACTG GGGCCGCCCCAGGCCGGGCTTCCAGCACCAGAGCGATGGTCAGGCTTCAGCTGGACGCAG ATTTCACCCCGCAGGGCACACGCAGACCCATTTGTTTGGAAGCGGCAGTCCTAAGGCAGT GCAGGTGCCTCCACGGCCCCAGCCCAGCTCTCCTGCAGGTGTAAAGGATGCAGATTCCAG GGCCCCCCATGGCCTGCAGAGGCCCCTCAGAGCAGGAAGGGCCGGGCTCTCGGGGAGCCC CCATCCCAGGTGCTGAGGTCCTTGGGTCACATGGAGCTGGGGTGGGGAGTGCCCAGGTCC CCTGTGATCCGATGGCCACGTTTCCCTCCTGGCTTCACGCACCCCAAGGGCTGGGGGTCC CACTCACTGCCCATTTTCTGGCTGTGGGGGGGGTCTGTTTTCTTCCACCTTCTCAAGGTG TTCAGAGCCTCAGGGGCCTCCCCACTTCCTCTGGGGCCTGGGGGAGTAGAGTCTGTCACC CGGAGGCTGTGTGCCTCCCCGCGACATTCCCCAGTGGCCGGGCCGACCAGGCAGGCTCTG CCTGTGGATGGGGCTGCTGAGCATGAGCGTGTGACCCCCATTTCTGAGCTGTGGGTGGAC CCACCGGGCCTGGGCCAAGGTTTTCAGGAGGCAGCTCTATTCTACTCCGCCATGGTGGCC TCCCTGAAAGGGGTGAGTGTAGAAGCCAGTTCCCTCTTCTGCGAGCCCCACCCCTACCCC AGGAGGACAATTCTTGTTCAGGGAGGGTCTCCCCACCCACTTCCCCACCCCACAGTGGCC CACAGGCCCCACCCTAGAGAGTACAAGGGGCTCCCCAGGCTGCTCACTGGCCCAGCCCCG CCCCACCTGGACTGCACCTGAAAATGGGCTCAGAGAGGCCAAGTGGCCCAAAAAGACGCT GCTGGGTGGGAAGGGGCGGTGGCCTCTGTGCCCGCAGTGCCCCTCCTGCCTCAAGGGTGT TGTCTGCCTGGCAGAGCCTGGGGTGTTCACAAAGCCCAGGCACCTGCAGCTGAGGGCAGG GGAGAGGGAAGGGAGCCACATCCAGGCGACGGGGCTGCTCGTCCTCCTGTGCGAGAGTGG GGAGACTCAGGCCAGCCCAAGTGGGCGGCGGCCCCGGTTGCTTGATCTAAGCTCTGCTCA CACTGCCCTGCCCTTCTGGGAGAGGGGTGGGCGCCAACTGACTCCTGGGCTGTCTGGGCT GGGGACCGGGATCTCAGACCCAGCCCCTCCCCTGGACAGGAGGAGCCAGTCCAGGGGACA GAGGGCTCAGTGGCTGGAGGGCAGGGCCAGGGTGCGGACACAAGCTGCAGGTACCACAGA AGTTTGCTCTGGGAGCCCCTCCTGGGCCCATGTGGCCCCAGGCTGGCCCAGGACAGAGGC GTGGGGTGGGAGCAGGGGGTCCCATCCTGAGTCACTGCCCTCCACAGACACAGACCATGG CCTTGCCAACGGCTCGACCCCTGTTGGGGTCCTGTGGGACCCCCGCCCTCGGCAGCCTCC TGTTCCTGCTCTTCAGCCTCGGTGCGTACTTGATGGGGCTGCTGGTGAGGTGGGGACGGC CCAGGGGCCTTGGGGGCCAGGCCCCCAGCAAGGCTTTGCCTGCCCCTGCCTTCTCCCTGG AGTGCCTGTGGTGGCCACGTCTCAGCAGCAGTCTCTGCCCCCAGAGGTGACTGGAGCTGG AGATCCAGCCAGGGAGTGATGGGGCTCAGGACACAGTGGGGATGTCTGTGGGATGGGTGG TCTGACCGGCCAAGCAGCCGGGTCTCAGGGAAAGATGTGGAAGGCCGGGCTCCCTGGTGG AGTCCCGACCCCTGTGCCTGGGGGACTGTGATGTCACGGGGTACATGGGCCTGAGCCACT GGCTTCTCTTTGGGGTGTGCACAGGGCTGGCTGTGGGGGCGGCCAGGCTCTGCCTCCTTC CTCCCCTGGGTCAGGGCACAGCCCAGAGGCCCGCCCCCTCCCCCAAGCTGTCCCCTCTGC CCCTTTAGGATGGGTGCAGCCCTCGAGGACCCTGGCTGGAGAGACAGGGCAGGTAAGGTC CCCTCTGGGGAAACAGGGGAGGGTCTTCAGGTCCCAGGTGGGGGTGCCATGCTGTGTTCT CTCTGTCACGTATCCACGGTGCTTGCCAGTTTCCACGGTCCTTGCTTGCAAAGGGGCACC TGGACCTGCATGTGACTGGCCTGGGAGCAGCCAGGTCCAGGGAGCGGCAGAGCTGAAATT GCAGCTGGGTCTGGGAAGTAGATGGATGAGAAGCAGCCAAGCCCATGGGTCTGAGACACA GCCAGGCCTGGGAAGTAGCTGAACTCGGGGAGTACCTGGCCCAGGGGTAGCGGGACCTGG GAACTCCTGCTCCAGAGAGCTGGTCTGAGCCATGTTCAGCAGGCCCTGTGTCCCCAGGAG GCTGCGCCCCTGGACGGAGTCCTGGCCAACCCACCTAACATTTCCAGGTGGGTCTGGGGT CCTCACAGTCCTCAAGGGTGAGGCTCGAGGGGCCCTCGGGACTGAGGGTGGGCAGGGCAC CCCATCCCCCAGCATCCCCTCCCCCTTCCTCCTCTGCTCCACCTCAGATCTGACTGGGCT CAGGACTGCGGGAGGGACTGACACCCCTCAGGTGATGGCAACTCCCGGCCCTTGAGGGCG TCACCTGGTCTTGGGGGGAGGTCTGCAGGGAGCACCAGGGTCCTTTGGGGAGAGGTGGGG CTGTGGGGCTTGGGGAGCACTGGGTGGACATTGCAGGGGAGGGGCGATCGTGGGTGCCCA GCCCGACCCTTCCTGCAGCCTCTCCCCTCGCCAACTCCTTGGCTTCCCGTGTGCGGAGGT GTCCGGCCTGAGCACGGAGCGTGTCCGGGAGCTGGCTGTGGCCTTGGCACAGAAGAATGT CAAGCTCTCAACAGAGCAGGTCAGTCTCAGTTGGGCTGAGGCAGGTGGGCACAGCTGGGG CTGAGGAATTCACAGGCAGCTCTGCAGTGCCCACCTTGCCACCACGGTCCCCTCTGTCCC TGCTGCCATCTCTCCCCGGCCAGTTCTTCCCAGAGTTCCTCTGGCCACCCAAGCTGACCA CTGGGGTGCCTGTCCACGTCAGGGGCTGGCTCCCCAGGAGCAAGTCTGATATGACGCTGT GTGCTGGGCCCCCTCCTGGAGCGCCGTGGGCAGCCCTCCAGGCTCTGCCCCAAGGGTGAA TCTTTTTCGGGGGAGTGGGTGAGATCTGGGGAAGGGGAGCGGAGCCAGGCACGGGAGCCC CCATCCCCCAGGGCAGCGCTGCAGGCGGCCAGAGATCCACTTCCACAGATTCTCGTGGCC AGGGCAGGGGTGTGTTGTGGTGGGCAGACTGGCCAGGCGACCCTGGCCCACCATGTGAGT GGCGGCTCGAAACGCTCTGTGCTGGACTCCCTGCCCCTGCAGCTGCGCTGTCTGGCTCAC CGGCTCTCTGAGCCCCCCGAGGACCTGGACGCCCTCCCATTGGACCTGCTGCTATTCCTC AAGTAGGCCCTGCCCCCTGAACCCACCCCCCCGGCTTTTGCCGCCAGCCCTCAGCCCCCA ACCCCCTGCCCCTTGCCTCGGATCCCAGGCCACAGCAGAGATGTGGAGGCCGGCCGGGCT GCCTCTCAGGGTGGGGACGGGTGTGATCAGTGCGGCCTGTCCCCAGCACCCTCTCTTCAC AGCCCAGATGCGTTCTCGGGGCCCCAGGCCTGCACCCGTTTCTTCTCCCGCATCACGAAG GCCAATGTGGACCTGCTCCCGAGGGGGGCTCCCGAGCGACAGCGGCTGCTGCCTGCGGCT CTGGCCTGCTGGGTAGGGGCTGGGGCCAGCGCGGGGCGGAGAGGGCTCGGCAGTTCCAAA AGCGCTGAGGCCAGCCTCTCTGCAGGGTGTGCGGGGGTCTCTGCTGAGCGAGGCTGATGT GCGGGCTCTGGGAGGCCTGGCTTGCGACCTGCCTGGGCGCTTTGTGGCCGAGTCGGCCGA AGTGCTGCTACCCCGGCTGGTGAGCTGCCCGGGACCCCTGGACCAGGACCAGCAGGAGGC AGCCAGGGCGGCTCTGCAGGGCGGGGGACCCCCCTACGGGTAAGTGAAGGTGTCTGGAAC CTCGAAGGCTCACCTGGCGGCGTGGTATCAGCAGCGTGAGGACACTTGCGGCCATGCCTC AAGGCCCAGGGTCAGTCACCCCCGCCACCACCCCTGCCAATGCCCCCAGCGTCCCCTCCA CAGCCAGGGGGTACGGCCTGGCCTCTTCCCTCTCTGGGGCTGCACGTGGGGGGTCCCTGA GCTGTGTCCCGTGTCTGCACAGCCCCCCGTCGACATGGTCTGTCTCCACGATGGACGCTC TGCGGGGCCTGCTGCCCGTGCTGGGCCAGCCCATCATCCGCAGCATCCCGCAGGTGAGAC CCCAATCCCCAGCCCGTGGGGATGCCCGGCCACCCGAGGCTCAGCCCAGGTCCTGCTCGT CCTCAGGGCATCGTGGCCGCGTGGCGGCAACGCTCCTCTCGGGACCCATCCTGGCGGCAG CCTGAACGGACCATCCTCCGGCCGCGGTTCCGGCGGGAAGTGGAGAGTGAGTGCCGTGCC CTGCGCAGTCTGGCACCAGGCTGGGCAGCACCCCTGGGGGTGGGCATCACTTTAGGGTCT CACCTGCCCCTCCCTGGCTCTGCAGCACATCCCATTATAATCACAGAGAGTGGACAGAAT CCCTGTTTGCCAGTGGGTAAACTGAGGCACAGGGAGGGTCACAAATGGCCCGAGGTCTCA TCTCACAGGAGGTGTGGGAGGAAGAAGGGGTCAAACGAACTCCGGCCCTGACCCCTGACC CCTGTGCCCTGCAGAGACAGCCTGTCCTTCAGGCAAGAAGGCCCGCGAGATAGACGAGAG CCTCATCTTCTACAAGAAGTGGGAGCTGGAAGCCTGCGTGGATGCGGCCCTGCTGGCCAC CCAGATGGACCGCGTGAACGCCATCCCCTTCACCTACGAGCAGCTGGACGTCCTAAAGCA TAAACTGGATGAGGTAGTTCATGACTCAAGTTCCCACCGGCCTGCTGTGTCCAAGCCATC CCCAGCCCCTCTGGGAGTGACATGGGCCCTCCTGGTCTCTTGGCCTGCAGCTCTACCCAC AAGGTTACCCCGAGTCTGTGATCCAGCACCTGGGCTACCTCTTCCTCAAGATGAGCCCTG AGGACATTCGCAAGTGGAATGTGACGTCCCTGGAGACCCTGAAGGCTTTGCTTGAAGTCA ACAAAGGGCACGAAATGAGTCCTCAGGTGACCGTCCGGCTCGGGGGTCATGTGGCATGAG ATTGGGAAGGGCTGAGGGGCAGAGTGGGGGACAAAGCCTGAGGTTGGGCGGGCCTGGGGT CAGGGGCACGGCCTGAGGTTATGCTGGTGGTGGAGGGATACATCTCTCCTTGCCACAAGG CTCCTCGGCGGCCCCTCCCACAGGTGGCCACCCTGATCGACCGCTTTGTGAAGGGAAGGG GCCAGCTAGACAAAGACACCCTAGACACCCTGACCGCCTTCTACCCTGGGTACCTGTGCT CCCTCAGCCCCGAGGAGCTGAGCTCCGTGCCCCCCAGCAGCATCTGGTGAGTCCCCAGAA CTCTGCCCGGCAAGGTGGGTCCGTGTGCTGGCGCTCACTGTCCACCCACCGTGTCCCCAG GGCGGTCAGGCCCCAGGACCTGGACACGTGTGACCCAAGGCAGCTGGACGTCCTCTATCC CAAGGCCCGCCTTGCTTTCCAGAACATGAACGGGTCCGAATACTTCGTGAAGATCCAGTC CTTCCTGGGTGAGCCAGGGAGTCCCTGGCCAGGGTGGGCAACACAACGGGGGAAGCACAG ACTCCACTCGGGGGTGCCAGGCCTTTGCCTCGCCGGGCCGTCTGCTGCCAGGGTAACTGG GTGGTCACCCGCCCTCTGCCCCCCGGGGTGTGTATGGCCTTAGGGGCTGTGGGTTCTGAC CCCAGCTCGGGGCGCCAGCCACCTCCAGGGTCTCCCACGCCTGGGGGTCAGGCGGCTAGG CAAACCCAGGCCCTGGAATCCCTAAGGAAAAAGGGAAGCCCTGTAAGGCAAGTGGGCTTC CTGCAGCCTGTGGTCAAGGGCCTGGGGGTGTGAGGTGAGGCCTCAGCTCGGGCCCCTCTC CCGGCGGGCAGGTGGGGCCCCCACGGAGGATTTGAAGGCGCTCAGTCAGCAGAATGTGAG CATGGACTTGGCCACGTTCATGAAGCTGCGGACGGATGCGGTGCTGGTATGGCGAGCGGG AGGAGGGGCGTGTGGAGGAGGGGCCCGTGGAGGAGGGGCGAGTGGGAGGAGGGGCGCGTG GAGGGGGGGCGTGTGGGGGGGTGCGTGGAGGAGGGGCGCGTGGAGGAGGGGCGCGTGGAG GGGGGAGCGTGGGGGGCGTGGAGGAGGGGCGCGTGGAGGAGGGGCGCGTGGAGGGGGGAG CGTGGGGGGCGTGGAGGAGGGGCGCGTGGAGGGGGGAGTGTGGGGGGGCGTGGAGGAGGA GGGGCGCATGGGGGGGTGTGGAGGGGGGCGCGTGGAGGAGGGGCGCGTGGAGGGGGGAGC GTGGGGGGCGTGGAGGAGGGGCGCGTGGAGGGGGGCGCGTGGGGGGGGCGCATGGGGGGG CGTGGAGGGGGGTGCGTGGAGGAGGGGCGCGTGGAGGAGGAGGGGCGCATGGGGGGGTGT GGAGGGGGGCGCGTGGAGGGGGCACGTGGAGGGGTCGCGTGGAGGAGGGGCGCGTGGAGG GGGCCGTGTGGGGGGGCGTGGAGGGGGGCGCGTGGAGGAGGAGGGGCGCATGGGGGGGTG TGGAGGGGGGCGCGTGGAGGGGGCGCGTGGAGGAGGGGCACATGGAGGGGGGGGCAAGTG GAGAAGCCCTGGTGGAGGGGCGCATGGAGGAGGGGCCAACGGGGGGTGGGAGGGCGTGTA AGGCGGGTCTGCAGTGGGGCGAGGCCTTAGGAAGGGCAGCATCTTCCCGTGTGGTGGGGC CTAGGGAAGGGCAGCCATTGAGCTGAGGTCAGCTGGCCGGAGACCTCCGAAGTCTGGAGA GGCTGCGGTGGGCATCTGTGGGTGGGGCAGTTTGGACACAGGAGAGCCTGGCAGCCCTCT GGCGGCGCTGAGGGAAGGAGACCCTCCTTGATGGCTGCCCGGGGTCTCTGGCAGCCGTTG ACTGTGGCTGAGGTGCAGAAACTTCTGGGACCCCACGTGGAGGGCCTGAAGGCGGAGGAG CGGCACCGCCCGGTGCGGGACTGGATCCTACGGCAGCGGCAGGACGACCTGGACACGCTG GGGCTGGGGCTACAGGGCGGCATCCCCAACGGCTACCTGGTCCTAGACCTCAGCATGCAA GGTGGGCGGGGCGGCCAGGCCAGGGCTGGGGGCAGAGCTGGGGGCGTGGAGGTGGGCGCT CTGAGTCACCCCTCTCTCTGTAGAGGCCCTCTCGGGGACGCCCTGCCTCCTAGGACCTGG ACCTGTTCTCACCGTCCTGGCACTGCTCCTAGCCTCCACCCTGGCCTGAGGGCCCCACTC CCTTGCTGGCCCCAGCCCTGCTGGGGATCCCCGCCTGGCCAGGAGCAGGCACGGGTGGTC CCCGTTCCACCCCAAGAGAACTCGCGCTCAGTAAACGGGAACATGCCCCCTGCAGACACG T OMIM ID 601051