| Entrez gene ID | | 10038 |
| Official gene symbol | | PARP2 |
| Full name | | poly (ADP-ribose) polymerase 2 |
| Aliases | | ,ADPRT2,ADPRTL2,ADPRTL3,PARP-2,pADPRT-2, |
| Gene summary | | This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq] |
| Location | | Chromosome: 14 Locus: 14q11.2-q12 |
| Gene position | | 20811773 - 20826063 Map Viewer |
| Gene orientation | | plus |
| Gene size | | 14291 bp |
| Gene sequence |
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| OMIM ID | | 607725 |