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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CDH5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1003
Official gene symbolCDH5
Full namecadherin 5, type 2 (vascular endothelium)
Aliases,7B4,CD144,FLJ17376,
Gene summaryThis gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq]
LocationChromosome: 16   Locus: 16q22.1
Gene position66400525 - 66438689  Map Viewer
Gene orientationplus
Gene size38165 bp
Gene sequence
OMIM ID601120