Drug Studies-in vitro
Last updated: 2025 Mar 18
Total hit(s): 1204
S.No.
1
40077853
Characterization of the binding features between SARS-CoV-2 5'-proximal transcripts of genomic RNA and nucleocapsid proteins.
RNA Biol
2025 Dec
1
2
40056806
Accurate evaluation of live-virus microneutralisation for SARS-CoV-2 variant JN.1 in the assessment of vaccination and therapeutics.
Vaccine
2025 Mar 7
3.31
1
3
39973207
Reactive oxygen species-mediated cytotoxic and DNA-damaging mechanism of N(4)-hydroxycytidine, a metabolite of the COVID-19 therapeutic drug molnupiravir.
Free Radic Res
2025 Mar 6
1
4
40038251
LNP-RNA-mediated antigen presentation leverages SARS-CoV-2-specific immunity for cancer treatment.
Nat Commun
2025 Mar 4
11.8
1
5
40025489
Switching of OAS1 splicing isoforms overcomes SNP-derived vulnerability to SARS-CoV-2 infection.
BMC Biol
2025 Mar 3
1
6
40035759
Structural basis of SARS-CoV-2 polymerase inhibition by nonnucleoside inhibitor HeE1-2Tyr.
Proc Natl Acad Sci U S A
2025 Mar 11
9.35
1
7
40069439
Functional Activity and Binding Specificity of Small Ankyrin Repeat Proteins Called Ankyrons Against SARS-CoV-2 Variants.
AAPS J
2025 Mar 11
3.43
1
8
39837387
Intranasal liposomal remdesivir induces SARS-CoV-2 clearance in K18-hACE2 mice and ensures survival.
J Control Release
2025 Mar 10
15.5
1
9
39843797
Empowering African Expertise: Enhancing Safety Data Integration and Signal Detection for COVID-19 Vaccines Through the African Union Smart Safety Surveillance Joint Signal Management Group.
Drug Saf
2025 Mar
3.64
1
10
39912497
Rapid bioreactor process optimization and scale-up for production of a measles vector COVID-19 vaccine candidate.
Biotechnol Prog
2025 Feb 6
2.51
1
11
39993141
Gag HIV-1 Virus-like Particles and Extracellular Vesicles Functionalization with Spike Epitopes of SARS-CoV-2 Using a Copper-Free Click Chemistry Approach.
Bioconjug Chem
2025 Feb 24
4.38
1
12
39988470
Novel Sulfonamide-Sydnone Hybrids: Complementary Insight into Anti-Inflammatory Action, Anti-SARS-CoV-2 Activity, Human Serum Albumin Interaction, and in silico Analysis.
ChemMedChem
2025 Feb 23
5.5
1
13
40013067
Dihydropyrimidine-2-thione derivatives as SARS-CoV-2 main protease inhibitors: synthesis, SAR and in vitro profiling.
RSC Adv
2025 Feb 19
1
14
39972932
Exploring natural compounds and synthetic derivatives as potential inhibitors of SARS-CoV-2 PLpro: a computational approach with enzyme inhibition and cytotoxicity assessment.
J Biomol Struct Dyn
2025 Feb 19
3.22
1
15
39948424
Intratumoral administration of mRNA COVID-19 vaccine delays melanoma growth in mice.
Sci Rep
2025 Feb 13
4.12
1
16
39943808
SARS-CoV-2 B Epitope-Guided Neoantigen NanoVaccines Enhance Tumor-Specific CD4/CD8 T Cell Immunity through B Cell Antigen Presentation.
ACS Nano
2025 Feb 12
13.7
1
17
39932973
A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses.
PLoS Pathog
2025 Feb 11
6.18
1
18
39908775
Porcine epidemic diarrhea coronavirus infection activates caspase-8 to enhance innate immunity by blocking CYLD-mediated deubiquitination of RIG-I.
Virology
2025 Feb 1
2.819
1
19
39941049
Subgenomic RNA Detection in SARS-CoV-2 Assessing Replication and Inactivation Through Serial Passages, RT-qPCR, and Electron Microscopy.
Int J Mol Sci
2025 Feb 1
4.21
1
20
39896880
Antiviral efficacy of fluoxetine in early symptomatic COVID-19: an open-label, randomised, controlled, adaptive platform trial (PLATCOV).
EClinicalMedicine
2025 Feb
6.68
1
21
39780400
Single-cell analysis of lung epithelial cells reveals age and cell population-specific responses to SARS-CoV-2 infection in ciliated cells.
Clin Exp Immunol
2025 Jan 9
3.7
1
22
39793935
Population pharmacokinetics and pharmacodynamics of HFB30132A, a monoclonal antibody against SARS-CoV-2, in healthy Chinese and US subjects.
Int J Antimicrob Agents
2025 Jan 8
4.6
1
23
39890847
Safety and efficacy of oral administrated cepharanthine in non-hospitalized, asymptomatic or mild COVID-19 patients: a Double-blind, randomized, placebo-controlled trial : Author detials.
Sci Rep
2025 Jan 31
4.12
1
24
39889765
Improving soluble recombinant SARS-CoV-2 papain-like protease production in Escherichia coli through chaperonin and maltose-binding protein tag: purification and kinetic characterization.
Prep Biochem Biotechnol
2025 Jan 31
1
25
39885485
Bidirectional approach of Punica granatum natural compounds: reduction in lung cancer and SARS-CoV-2 propagation.
BMC Complement Med Ther
2025 Jan 30
1