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Gastrointestinal

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Total hit(s): 26

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Diarrhea and Abdominal pain were the only gastrointestinal symptoms with 5.9% prevalence each, out of 187 symptomatic cases.

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33513332
(Emerg Infect Dis)

PMID	33513332 Date of Publishing: 2021 Mar
Title	Epidemiology and Clinical Course of First Wave Coronavirus Disease Cases, Faroe Islands
Author(s) name	Kristiansen MF, Heimustovu BH et al.
Journal	Emerg Infect Dis
Impact factor	6.81 Citation count: 6

NLM format
Kristiansen MF, Heimustovu BH, Borg SÁ, Mohr TH, Gislason H, Møller LF, Christiansen DH, Steig BÁ, Petersen MS, Strøm M, Gaini S. Epidemiology and Clinical Course of First Wave Coronavirus Disease Cases, Faroe Islands. Emerg Infect Dis. 2021 Mar;27(3):749-758. PMID:33513332

Gastrointestinal symptoms cluster was the third frequent cluster with 10% occurrence rate (16,518). Non-communicable diseases (Hypertension, Diabetes, Obesity) were more prevalent in symptomatic than presymptomatic cases.

Presymptomatic carriers were observed in 13% (25,520) of the SARS-CoV-2 cases with no symptoms on test day and previous days. More common among older adults (31%) than children (26%). ✍

33434668
(Int J Infect Dis)

PMID	33434668 Date of Publishing: 2021 Jan 9
Title	Epidemiology of COVID-19 in Mexico: Symptomatic profiles and presymptomatic people
Author(s) name	Fernández-Rojas MA, Luna-Ruiz Esparza MA et al.
Journal	Int J Infect Dis
Impact factor	3.42 Citation count: 11

NLM format
Fernández-Rojas MA, Luna-Ruiz Esparza MA, Campos-Romero A, Calva-Espinosa DY, Moreno-Camacho JL, Langle-Martínez AP, García-Gil A, Solís-González CJ, Canizalez-Román A, León-Sicairos N, Alcántar-Fernández J. Epidemiology of COVID-19 in Mexico: Symptomatic profiles and presymptomatic people. Int J Infect Dis. 2021 Mar;104:572-579. PMID:33434668

A case study of a 52 year old man with SARS-CoV-2 infection who developed vesicular skin eruptions and subsequent GI symptons but not any typical symptoms associated with COVID-19.

The patient did not have any respiratory symptoms ✍

33471878
(Cutis)

PMID	33471878 Date of Publishing: 2020 Dec
Title	Skin eruption and gastrointestinal symptoms as presentation of COVID-19
Author(s) name	Chu S, Christensen LF, Vidmar D.
Journal	Cutis
Impact factor	0.47 Citation count: 1

28.6% of liver transplant recipients with COVID-19 presented diarrhea as a gastrointestinal symptom.

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32891405
(Transplant Proc)

PMID	32891405 Date of Publishing: 2020 Nov
Title	Clinical Presentation, Treatment, and Mortality Rate in Liver Transplant Recipients With Coronavirus Disease 2019: A Systematic Review and Quantitative Analysis
Author(s) name	Fraser J, Mousley J et al.
Journal	Transplant Proc
Impact factor	0.95 Citation count: 19

NLM format
Fraser J, Mousley J, Testro A, Smibert OC, Koshy AN. Clinical Presentation, Treatment, and Mortality Rate in Liver Transplant Recipients With Coronavirus Disease 2019: A Systematic Review and Quantitative Analysis. Transplant Proc. 2020 Nov;52(9):2676-2683. PMID:32891405

Most common gastrointestinal symptom was Sore throat (13.7%) and least common was Nausea (1.3%) out of 64 symptomatic cases.

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33154280
(Niger Postgrad Med J)

PMID	33154280 Date of Publishing: 2020 Oct-Dec
Title	Clinical characteristics, predictors of symptomatic coronavirus disease 2019 and duration of hospitalisation in a cohort of 632 Patients in Lagos State, Nigeria
Author(s) name	Erinoso OA, Wright KO et al.
Journal	Niger Postgrad Med J
Impact factor	1.2 Citation count: 4

NLM format

Erinoso OA, Wright KO, Anya S, Bowale A, Adejumo O, Adesola S, Osikomaiya B, Mutiu B, Saka B, Falana A, Ola-Ayinde D, Akase EI, Owuna H, Abdur-Razzaq H, Lajide D, Ezechi O, Ogboye O, Osibogun A, Abayomi A. Clinical characteristics, predictors of symptomatic coronavirus disease 2019 and duration of hospitalisation in a cohort of 632 Patients in Lagos State, Nigeria. Niger Postgrad Med J. 2020 Oct-Dec;27(4):285-292. PMID:33154280

6 gastrointestinal symptoms were reported in 139 patients.

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32077115
(Allergy)

PMID	32077115 Date of Publishing: 2020 Jul
Title	Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China
Author(s) name	Zhang JJ, Dong X et al.
Journal	Allergy
Impact factor	8.7 Citation count: 1555

NLM format
Zhang JJ, Dong X, Cao YY, Yuan YD, Yang YB, Yan YQ, Akdis CA, Gao YD. Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China . Allergy. 2020 Jul;75(7):1730-1741. PMID:32077115

Statistical analysis of patients with SARS-CoV-2 showing GI symptoms and fever, and infering the risk of severe illness and death.

1. The patients with fever and no GI symptoms were around 63.9%. ✍

32606209
(Gut)

PMID	32606209 Date of Publishing: 2020 Jun 30
Title	GI symptoms and fever increase the risk of severe illness and death in patients with COVID-19
Author(s) name	Liu J, Tao L et al.
Journal	Gut
Impact factor	15.78 Citation count: 3

NLM format
Liu J, Tao L, Liu X, Yao H, Yu S, Wang Q, Zhang J, Gao Z, Jiang R, Jing W, Liu M. GI symptoms and fever increase the risk of severe illness and death in patients with COVID-19. Gut. 2021 Feb;70(2):442-444. PMID:32606209

The entry of virus through angiotensin-converting enzyme 2 causes digestive symptoms. Patients detected with viral nucleic acid in the feces had longer recovery period as well as higher viral count.

The study was performed at Union Hospital, Tongji Medical College (Wuhan, China) ✍

32301761
(Am J Gastroenterol)

PMID	32301761 Date of Publishing: 2020 Jun
Title	Digestive Symptoms in COVID-19 Patients With Mild Disease Severity: Clinical Presentation, Stool Viral RNA Testing, and Outcomes
Author(s) name	Han C, Duan C et al.
Journal	Am J Gastroenterol
Impact factor	6.73 Citation count: 243

NLM format
Han C, Duan C, Zhang S, Spiegel B, Shi H, Wang W, Zhang L, Lin R, Liu J, Ding Z, Hou X. Digestive Symptoms in COVID-19 Patients With Mild Disease Severity: Clinical Presentation, Stool Viral RNA Testing, and Outcomes. Am J Gastroenterol. 2020 Jun;115(6):916-923. PMID:32301761

A 68 year old man positive for SARS-CoV-2 experieced vomitting and fever, no other symptoms were reported.

Epidemiologic history : Relative exposed to Wuhan Medical History: Over the counter antiemetic to ease vomitting Treatment: -interferon atomization inhalation (5 million U per time, Bid), oral lopinavir/ritonavir (2 capsules each time, Bid) and ribavirin 500 mg (intravenous infusion, Bid). Xuebijing (100 ml, Bid) + chinese herbs ✍

32347435
(Dig Dis Sci)

PMID	32347435 Date of Publishing: 2020 Jun
Title	SARSCoV2Induced Vomiting as Onset Symptom in a Patient with COVID19
Author(s) name	Fu B, Qian K, Fu X.
Journal	Dig Dis Sci
Impact factor	3.01 Citation count: 6

The paper reports that digestive system along with respiratory tract could be a potential route of infection. Hence some patients with SARS-CoV-2 infection might only exhibit Gastrointestinal symptoms without fever or respiratory manifestations.

Epidemiologic history Close contact with infected person : 94 Environmental exposure : 99 ✍

32205220
(Clin Gastroenterol Hepatol)

PMID	32205220 Date of Publishing: 2020 Jun
Title	Don't Overlook Digestive Symptoms in Patients With 2019 Novel Coronavirus Disease (COVID-19)
Author(s) name	Luo S, Zhang X, Xu H.
Journal	Clin Gastroenterol Hepatol
Impact factor	5.3 Citation count: 164

NLM format
Luo S, Zhang X, Xu H. Don't Overlook Digestive Symptoms in Patients With 2019 Novel Coronavirus Disease (COVID-19). Clin Gastroenterol Hepatol. 2020 Jun;18(7):1636-1637. PMID:32205220

About 254 patietnts with clinically confirmed Novel coronavirus-infected pneumonia (NCIP) were enrolled in order to study the frequency of GI symptoms in COVID-19 patients.

Medical and non-medical staff were counted and analysed separately. As evidenced by our case report, this knowledge gap can lead to a delay in diagnosis and will increase the opportunity for viral transmission to other people including healthcare workers. ✍

32199880
(Gastroenterology)

PMID	32199880 Date of Publishing: 2020 Jun
Title	Effect of Gastrointestinal Symptoms in Patients With COVID-19
Author(s) name	Zhou Z, Zhao N et al.
Journal	Gastroenterology
Impact factor	15.13 Citation count: 104

A 22-yr-old COVID-19 positive man with a travel history to Wuhan had a 4-day history of diarrhoea (34 times a day) and fever (100.94 F) on admission.

The patitent had a travel history to Wuhan,China. ✍

32139552
(Gut)

PMID	32139552 Date of Publishing: 2020 Jun
Title	SARS-CoV-2 induced diarrhoea as onset symptom in patient withCOVID-19
Author(s) name	Song Y, Liu P et al.
Journal	Gut
Impact factor	15.78 Citation count: 159

NLM format
Song Y, Liu P, Shi XL, Chu YL, Zhang J, Xia J, Gao XZ, Qu T, Wang MY. SARS-CoV-2 induced diarrhoea as onset symptom in patient withCOVID-19. Gut. 2020 Jun;69(6):1143-1144. PMID:32139552

Epidemiological, demographic, clinical and laboratory data of 95 cases with SARS-CoV-2 along with GI manifestations were analysed.

45 out of 58 had a travel history to Wuhan, China. ✍

32241899
(Gut)

PMID	32241899 Date of Publishing: 2020 Jun
Title	Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection
Author(s) name	Lin L, Jiang X et al.
Journal	Gut
Impact factor	15.78 Citation count: 386

NLM format
Lin L, Jiang X, Zhang Z, Huang S, Zhang Z, Fang Z, Gu Z, Gao L, Shi H, Mai L, Liu Y, Lin X, Lai R, Yan Z, Li X, Shan H. Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection. Gut. 2020 Jun;69(6):997-1001. PMID:32241899

A 22-yr-old COVID-19 positive man with a travel history to Wuhan had a 4-day history of diarrhoea (34 times a day) and fever (100.94 F) on admission.

The patitent had a travel history to Wuhan,China. ✍

32139552
(Gut)

PMID	32139552 Date of Publishing: 2020 Jun
Title	SARS-CoV-2 induced diarrhoea as onset symptom in patient withCOVID-19
Author(s) name	Song Y, Liu P et al.
Journal	Gut
Impact factor	15.78 Citation count: 159

NLM format
Song Y, Liu P, Shi XL, Chu YL, Zhang J, Xia J, Gao XZ, Qu T, Wang MY. SARS-CoV-2 induced diarrhoea as onset symptom in patient withCOVID-19. Gut. 2020 Jun;69(6):1143-1144. PMID:32139552

A 68 year old man positive for SARS-CoV-2 experieced vomitting and fever, no other symptoms were reported.

32347435
(Dig Dis Sci)

PMID	32347435 Date of Publishing: 2020 Jun
Title	SARSCoV2Induced Vomiting as Onset Symptom in a Patient with COVID19
Author(s) name	Fu B, Qian K, Fu X.
Journal	Dig Dis Sci
Impact factor	3.01 Citation count: 6

Epidemiologic history Close contact with infected person : 94 Environmental exposure : 99 ✍

32205220
(Clin Gastroenterol Hepatol)

PMID	32205220 Date of Publishing: 2020 Jun
Title	Don't Overlook Digestive Symptoms in Patients With 2019 Novel Coronavirus Disease (COVID-19)
Author(s) name	Luo S, Zhang X, Xu H.
Journal	Clin Gastroenterol Hepatol
Impact factor	5.3 Citation count: 164

NLM format
Luo S, Zhang X, Xu H. Don't Overlook Digestive Symptoms in Patients With 2019 Novel Coronavirus Disease (COVID-19). Clin Gastroenterol Hepatol. 2020 Jun;18(7):1636-1637. PMID:32205220

About 254 patietnts with clinically confirmed Novel coronavirus-infected pneumonia (NCIP) were enrolled in order to study the frequency of GI symptoms in COVID-19 patients.

32199880
(Gastroenterology)

PMID	32199880 Date of Publishing: 2020 Jun
Title	Effect of Gastrointestinal Symptoms in Patients With COVID-19
Author(s) name	Zhou Z, Zhao N et al.
Journal	Gastroenterology
Impact factor	15.13 Citation count: 104

Epidemiological, demographic, clinical and laboratory data of 95 cases with SARS-CoV-2 along with GI manifestations were analysed.

45 out of 58 had a travel history to Wuhan, China. ✍

32241899
(Gut)

PMID	32241899 Date of Publishing: 2020 Jun
Title	Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection
Author(s) name	Lin L, Jiang X et al.
Journal	Gut
Impact factor	15.78 Citation count: 386

NLM format
Lin L, Jiang X, Zhang Z, Huang S, Zhang Z, Fang Z, Gu Z, Gao L, Shi H, Mai L, Liu Y, Lin X, Lai R, Yan Z, Li X, Shan H. Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection. Gut. 2020 Jun;69(6):997-1001. PMID:32241899

A 74-yr-old COVID-19 positive man with a travel history to Scotland had a 3-day history of diarrhoea (3 times/day) and vomiting (3 times/day) prior to admission.

There was no significant difference in the clinical outcomes (remained in hospital, discharged or died) between patients with and without GI symptoms. SARS-CoV-2 RNA could be detected in the oesophagus, stomach, duodenum and rectum in severe patients. Travel history to Scotland , 7 days prior to admission. past medical history of quiescent Ulcerative Colitis and Hypertension. ✍

32429041
(Geriatrics (Basel))

PMID	32429041 Date of Publishing: 2020 May 15
Title	COVID-19 and Gastrointestinal Symptoms-A Case Report
Author(s) name	Mackett AJ, Keevil VL.
Journal	Geriatrics (Basel)
Impact factor	- n/a - Citation count: 4

A 74-yr-old COVID-19 positive man with a travel history to Scotland had a 3-day history of diarrhoea (3 times/day) and vomiting (3 times/day) prior to admission.

32429041
(Geriatrics (Basel))

PMID	32429041 Date of Publishing: 2020 May 15
Title	COVID-19 and Gastrointestinal Symptoms-A Case Report
Author(s) name	Mackett AJ, Keevil VL.
Journal	Geriatrics (Basel)
Impact factor	- n/a - Citation count: 4

The study found that apart from respiratory symptoms, digestive distress such as lack of appetite, Diarrhea, vomiting, abdominal pain are also the symptoms associated with COVID-19 disease. COVID-19 associated digestive symptoms were diagnosed at later stages due to lack of knowledge.

The study was conducted on 3 heavily affected hospitals in Hubei province during the initial outbreak. ✍

32287140
(Am J Gastroenterol)

PMID	32287140 Date of Publishing: 2020 May
Title	Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study.
Author(s) name	Pan L, Mu M et al.
Journal	Am J Gastroenterol
Impact factor	6.73 Citation count: 721

NLM format
Pan L, Mu M, Yang P, Sun Y, Wang R, Yan J, Li P, Hu B, Wang J, Hu C, Jin Y, Niu X, Ping R, Du Y, Li T, Xu G, Hu Q, Tu L. Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study.. Am J Gastroenterol. 2020 May;115(5):766-773. PMID:32287140

A case study of a 66 yr-old woman infected with an unsual SARS-CoV-2 infection, dominated by gastrointestinal symptoms.

A two week travel history to Rome, Italy, and the symptoms appeared in a week after travel. ✍

32250094
(Pol Arch Intern Med)

PMID	32250094 Date of Publishing: 2020 Apr 30
Title	Gastrointestinal symptoms as the first, atypical indication of severe acute respiratory syndrome coronavirus 2 infection
Author(s) name	Pazgan-Simon M, Rorat M et al.
Journal	Pol Arch Intern Med
Impact factor	3.007 Citation count: 8

NLM format
Pazgan-Simon M, Rorat M, Buczyńska I, Zińczuk A, Simon K. Gastrointestinal symptoms as the first, atypical indication of severe acute respiratory syndrome coronavirus 2 infection. Pol Arch Intern Med. 2020 Apr 30;130(4):338-339. PMID:32250094

Gastrointestinal symptoms such as Diarrhoea and Nausea was observed in 10% of patients whereas Vomiting and Abdominal pain was seen in 2-3%.

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32031570
(JAMA)

PMID	32031570 Date of Publishing: 2020 Mar 17
Title	Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China
Author(s) name	Wang D, Hu B et al.
Journal	JAMA
Impact factor	14.78 Citation count: 9674

NLM format
Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, Zhao Y, Li Y, Wang X, Peng Z. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020 Mar 17;323(11):1061-1069. PMID:32031570

Minor gastrointestinal symptoms such as Diarrhoea and Vomiting were reported in the patients.

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32007143
(Lancet)

PMID	32007143 Date of Publishing: 2020 Feb 15
Title	Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Author(s) name	Chen N, Zhou M et al.
Journal	Lancet
Impact factor	43.38 Citation count: 8340

NLM format
Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, Qiu Y, Wang J, Liu Y, Wei Y, Xia J, Yu T, Zhang X, Zhang L. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020 Feb 15;395(10223):507-513. PMID:32007143

Epidemiological, radiographic, clinical and laboratory data of 7 patients with SARS-CoV-2 along with GI manifestations were analysed.

1. The laboratory examination showed that all patients had increased C-reactive protein, accelerated erythrocyte sedimentation rate, hypoproteinemia, mild electrolyte disturbances. 2. Most patients also showed a lower count of white blood cells and lymphocytes. 3. Persistent lymphopenia was seen in severe patients. ✍

32656221
(Front Med (Lausanne))

PMID	32656221 Date of Publishing: 2020
Title	Clinical Characteristics of COVID-19 Patients With Gastrointestinal Symptoms: An Analysis of Seven Patients in China.
Author(s) name	Ai JW, Zi H et al.
Journal	Front Med (Lausanne)
Impact factor	3 Citation count: 11

NLM format
Ai JW, Zi H, Wang Y, Huang Q, Wang N, Li LY, Pei B, Ji J, Zeng XT. Clinical Characteristics of COVID-19 Patients With Gastrointestinal Symptoms: An Analysis of Seven Patients in China.. Front Med (Lausanne). 2020 Jun 9;7:308. PMID:32656221