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Viral shedding
Last updated: 2022 Feb 21
Total hit(s): 6
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Original Article
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Hamsters infected with 10
3
TCID
50
of BavPat
(D614G)
strain showed median viral
RNA
copies of 4 x 10
6
/mg of
lung
tissue, infectious viral loads of 2 x 10
4
/mg of
lung
tissue , and weight change of 0.65%. Hamsters infected with 10
3
TCID
50
omicron
(B.1.1.529)
SARS-CoV-2 variant showed median viral
RNA
copies of 3 x 10
3
/mg of
lung
tissue, no infectious viral loads, and weight gain of about 3.8%.
Highly mutated spike of the omicron variant is better adapted to human ACE2 receptor when compare to ACE2 receptor of the hamster.
✍
35066015
(
Antiviral Res
)
PMID
35066015
Date of Publishing
: 2022 Jan 21
Title
The omicron (B.1.1.529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters
Author(s) name
Abdelnabi R, Foo CS et al.
Journal
Antiviral Res
Impact factor
4.12
Citation count
: 15
Date of Entry
2022 Feb 21
×
NLM format
Abdelnabi R, Foo CS, Zhang X, Lemmens V, Maes P, Slechten B, Raymenants J, André E, Weynand B, Dallmeier K, Neyts J. The omicron (B.1.1.529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters. Antiviral Res. 2022 Feb;198:105253. PMID:35066015
The virus titers in the tracheal and
lung
tissues of infected Hamsters showed higher virus replication in the
lung
tissues of hamsters infected with WT SARS-CoV-2 than Del-mut-1 variant infected hamsters.
✍
32301390
(
Emerg Microbes Infect
)
PMID
32301390
Date of Publishing
: 2020 Dec
Title
Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction
Author(s) name
Lau SY, Wang P et al.
Journal
Emerg Microbes Infect
Impact factor
5.84
Citation count
: 142
×
NLM format
Lau SY, Wang P, Mok BW, Zhang AJ, Chu H, Lee AC, Deng S, Chen P, Chan KH, Song W, Chen Z, To KK, Chan JF, Yuen KY, Chen H. Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction. Emerg Microbes Infect. 2020 Dec;9(1):837-842. PMID:32301390
Hamsters infected with mutant SARS-CoV-2 (G614 virus) showed higher viral load in the nasal washes and the tracheae, but not in the
lungs,
than those of Hamsters infected with WT SARS-CoV-2 (D614 virus).
Infected hamsters from both groups showed similar weight loss.
✍
33106671
(
Nature
)
PMID
33106671
Date of Publishing
: 2020 Oct 26
Title
Spike mutation D614G alters SARS-CoV-2 fitness
Author(s) name
Plante JA, Liu Y et al.
Journal
Nature
Impact factor
24.36
Citation count
: 651
×
NLM format
Plante JA, Liu Y, Liu J, Xia H, Johnson BA, Lokugamage KG, Zhang X, Muruato AE, Zou J, Fontes-Garfias CR, Mirchandani D, Scharton D, Bilello JP, Ku Z, An Z, Kalveram B, Freiberg AN, Menachery VD, Xie X, Plante KS, Weaver SC, Shi PY. Spike mutation D614G alters SARS-CoV-2 fitness. Nature. 2021 Apr;592(7852):116-121. PMID:33106671
12-24 months old male and female ferrets inoculated with SARS-CoV-2 virus had highest viral
RNA
in nasal washes. Viral
RNA
was also detected in saliva specimens.
✍
32259477
(
Cell Host Microbe
)
PMID
32259477
Date of Publishing
: 2020 May 13
Title
Infection and Rapid Transmission of SARS-CoV-2 in Ferrets
Author(s) name
Kim YI, Kim SG et al.
Journal
Cell Host Microbe
Impact factor
10.45
Citation count
: 442
×
NLM format
Kim YI, Kim SG, Kim SM, Kim EH, Park SJ, Yu KM, Chang JH, Kim EJ, Lee S, Casel MAB, Um J, Song MS, Jeong HW, Lai VD, Kim Y, Chin BS, Park JS, Chung KH, Foo SS, Poo H, Mo IP, Lee OJ, Webby RJ, Jung JU, Choi YK. Infection and Rapid Transmission of SARS-CoV-2 in Ferrets. Cell Host Microbe. 2020 May 13;27(5):704-709.e2. PMID:32259477
12-24 months old male and female ferrets infected through direct contact with infected ferrets had viral
RNA
in nasal washes, saliva, fecal and urine samples.
✍
32259477
(
Cell Host Microbe
)
PMID
32259477
Date of Publishing
: 2020 May 13
Title
Infection and Rapid Transmission of SARS-CoV-2 in Ferrets
Author(s) name
Kim YI, Kim SG et al.
Journal
Cell Host Microbe
Impact factor
10.45
Citation count
: 442
×
NLM format
Kim YI, Kim SG, Kim SM, Kim EH, Park SJ, Yu KM, Chang JH, Kim EJ, Lee S, Casel MAB, Um J, Song MS, Jeong HW, Lai VD, Kim Y, Chin BS, Park JS, Chung KH, Foo SS, Poo H, Mo IP, Lee OJ, Webby RJ, Jung JU, Choi YK. Infection and Rapid Transmission of SARS-CoV-2 in Ferrets. Cell Host Microbe. 2020 May 13;27(5):704-709.e2. PMID:32259477
2 out of 6 12-24 months old male and female ferrets in indirect contact with infected ferrets had viral
RNA
in nasal washes and fecal specimens.
✍
32259477
(
Cell Host Microbe
)
PMID
32259477
Date of Publishing
: 2020 May 13
Title
Infection and Rapid Transmission of SARS-CoV-2 in Ferrets
Author(s) name
Kim YI, Kim SG et al.
Journal
Cell Host Microbe
Impact factor
10.45
Citation count
: 442
×
NLM format
Kim YI, Kim SG, Kim SM, Kim EH, Park SJ, Yu KM, Chang JH, Kim EJ, Lee S, Casel MAB, Um J, Song MS, Jeong HW, Lai VD, Kim Y, Chin BS, Park JS, Chung KH, Foo SS, Poo H, Mo IP, Lee OJ, Webby RJ, Jung JU, Choi YK. Infection and Rapid Transmission of SARS-CoV-2 in Ferrets. Cell Host Microbe. 2020 May 13;27(5):704-709.e2. PMID:32259477