| In a SARS-CoV-2 HIV-positive patient, virus isolation in feces was reported when there was clinical improvement, and viable virus was not detectable in respiratory specimens. | Further research into fecaloral transmission, including subgroups such as immunocompromised individuals, is needed. ✍ | 33966675 (Infect Control Hosp Epidemiol)
PMID | 33966675 Date of Publishing: 2021 May 10 | Title | Temporal differences in culturable severe acute respiratory coronavirus virus 2 (SARS-CoV-2) from the respiratory and gastrointestinal tracts in a patient with moderate coronavirus disease 2019 (COVID-19) | Author(s) name | Audsley JM, Holmes NE et al. | Journal | Infect Control Hosp Epidemiol | Impact factor | 2.66 Citation count: 1 | Date of Entry | 2021 Dec 15 |
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Audsley JM, Holmes NE, Mordant FL, Douros C, Zufan SE, Nguyen THO, Kedzierski L, Rowntree LC, Hensen L, Subbarao K, Kedzierska K, Nicholson S, Sherry N, Thevarajan I, Tran T, Druce J. Temporal differences in culturable severe acute respiratory coronavirus virus 2 (SARS-CoV-2) from the respiratory and gastrointestinal tracts in a patient with moderate coronavirus disease 2019 (COVID-19). Infect Control Hosp Epidemiol. 2021 May 10:1-3. PMID:33966675 |
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| In severly ill patients, 8/12 (66.7%) showed viral shedding in a variety of tissues 20-40 days after disease onset. In 9/11 mildly ill patients, viral shedding was restrcited to the respiratory tract and 10 days after disease onset, no RNA was detectable. | ✍ | 32634129 (J Clin Invest)
PMID | 32634129 Date of Publishing: 2020 Oct 1 | Title | Kinetics of viral load and antibody response in relation to COVID-19 severity | Author(s) name | Wang Y, Zhang L et al. | Journal | J Clin Invest | Impact factor | 10.51 Citation count: 264 | Date of Entry | 2021 Sep 4 |
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Wang Y, Zhang L, Sang L, Ye F, Ruan S, Zhong B, Song T, Alshukairi AN, Chen R, Zhang Z, Gan M, Zhu A, Huang Y, Luo L, Mok CKP, Al Gethamy MM, Tan H, Li Z, Huang X, Li F, Sun J, Zhang Y, Wen L, Li Y, Chen Z, Zhuang Z, Zhuo J, Chen C, Kuang L, Wang J, Lv H, Jiang Y, Li M, Lin Y, Deng Y, Tang L, Liang J, Huang J, Perlman S, Zhong N, Zhao J, Malik Peiris JS, Li Y, Zhao J. Kinetics of viral load and antibody response in relation to COVID-19 severity. J Clin Invest. 2020 Oct 1;130(10):5235-5244. PMID:32634129 |
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| The maximum duration of viral shedding was from stools (46 days after discharge) among 9 positive children. | Median age of the participants is 85 months. 44% of the participants were male. ✍ | 32515685 (Emerg Microbes Infect)
PMID | 32515685 Date of Publishing: 2020 Dec | Title | Dynamic surveillance of SARS-CoV-2 shedding and neutralizing antibody in children with COVID-19
| Author(s) name | Liu P, Cai J et al. | Journal | Emerg Microbes Infect | Impact factor | 5.84 Citation count: 35 |
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Liu P, Cai J, Jia R, Xia S, Wang X, Cao L, Zeng M, Xu J. Dynamic surveillance of SARS-CoV-2 shedding and neutralizing antibody in children with COVID-19
. Emerg Microbes Infect. 2020 Dec;9(1):1254-1258. PMID:32515685 |
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| The duration of viral shedding, detected in stool and whole blood was 12 days. | ✍ | 32125362 (JAMA)
PMID | 32125362 Date of Publishing: 2020 Apr 21 | Title | Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore | Author(s) name | Young BE, Ong SWX et al. | Journal | JAMA | Impact factor | 14.78 Citation count: 966 |
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Young BE, Ong SWX, Kalimuddin S, Low JG, Tan SY, Loh J, Ng OT, Marimuthu K, Ang LW, Mak TM, Lau SK, Anderson DE, Chan KS, Tan TY, Ng TY, Cui L, Said Z, Kurupatham L, Chen MI, Chan M, Vasoo S, Wang LF, Tan BH, Lin RTP, Lee VJM, Leo YS, Lye DC; Singapore 2019 Novel Coronavirus Outbreak Research Team. Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore. JAMA. 2020 Apr 21;323(15):1488-1494. PMID:32125362 |
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| The duration of viral shedding in a 33-year-old woman, a 61-year-old man and a 75-year-old man was 55 days, 59 days and 63 days, respectively. | ✍ | 33282072 (Pan Afr Med J)
PMID | 33282072 Date of Publishing: 2020 | Title | Three COVID-19 cases with a long-term viral shedding period in Tunisia | Author(s) name | Bennasrallah C, Bannour R et al. | Journal | Pan Afr Med J | Impact factor | 0.4 Citation count: 3 |
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Bennasrallah C, Bannour R, Jlassi O, Kacem M, Fredj MB, Abroug H, Zemni I, Garrach B, Bahri R, Charfeddine N, Triki S, Sriha AB. Three COVID-19 cases with a long-term viral shedding period in Tunisia. Pan Afr Med J. 2020 Jul 16;35(Suppl 2):117. PMID:33282072 |
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