Risk factors

Last updated: 2022 Feb 28
Total hit(s): 58
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The hazard ratio (HR ; Covid-19 vs contemporary control) and 1-year burden (per 1,000 people) of post-acute Covid-19 cerebrovascular outcomes (stroke and transient ischemic episodes) are 1.53 and 5.48, respectively . The risks were present regardless of age, race, sex, or other cardiovascular risk factors such as obesity, hypertension, diabetes, chronic kidney disease, or hyperlipidemia; they were also present in people who had never had a heart attack or stroke before being exposed to COVID-19, indicating that these risks may manifest even in people who are not at high risk of heart disease.
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 		35132265
(Nat Med)
PMID
35132265
Date of Publishing: 2022 Feb 7
Title Long-term cardiovascular outcomes of COVID-19
Author(s) nameXie Y, Xu E et al.
Journal Nat Med
Impact factor
22.66
Citation count: 36
Date of Entry 2022 Feb 28

Incidence of post-acute Covid-19 composite of dysrhythmia outcomes (atrial fibrillation, sinus tachycardia, sinus bradycardia, ventricular arrhythmias, atrial flutter) had a hazard ratio (HR - COVID-19 vs Contemporary control) of 1.69 and a 1-year burden (per 1,000 people) of 19.86. Extrapulmonary (including cardiovascular) post-acute sequelae of COVID-19 have also been attributed to an abnormal chronic hyperactivated immune response, autoimmune, or virus persistence in immune-privileged areas.
✍
 		35132265
(Nat Med)
PMID
35132265
Date of Publishing: 2022 Feb 7
Title Long-term cardiovascular outcomes of COVID-19
Author(s) nameXie Y, Xu E et al.
Journal Nat Med
Impact factor
22.66
Citation count: 36
Date of Entry 2022 Feb 28

The hazard ratio (HR -COVID-19 vs Contemporary control) for post-acute Covid-19 inflammatory illness of the heart or pericardium (pericarditis, myocarditis) was 2.02 and 1-year burden (per 1,000 persons) was 1.23. The mechanism(s) behind the link between COVID-19 and the development of cardiovascular illnesses in the post-acute phase of the disease are not completely understood.
✍
 		35132265
(Nat Med)
PMID
35132265
Date of Publishing: 2022 Feb 7
Title Long-term cardiovascular outcomes of COVID-19
Author(s) nameXie Y, Xu E et al.
Journal Nat Med
Impact factor
22.66
Citation count: 36
Date of Entry 2022 Feb 28

The hazard ratio (HR) for post-acute Covid-19 Ischemic heart disease (acute coronary disease, myocardial infarction, ischemic cardiomyopathy, and angina) was 1.66, with a 1-year burden of 7.28 per 1,000 people. Even among those who did not require hospitalisation because to acute COVID-19, the risks and consequences of cardiovascular disease were evident.
✍
 		35132265
(Nat Med)
PMID
35132265
Date of Publishing: 2022 Feb 7
Title Long-term cardiovascular outcomes of COVID-19
Author(s) nameXie Y, Xu E et al.
Journal Nat Med
Impact factor
22.66
Citation count: 36
Date of Entry 2022 Feb 28

The hazard ratio (HR) for post-acute Covid-19 thromboembolic diseases (pulmonary embolism, deep vein thrombosis, and superficial vein thrombosis) was 2.39, with a one-year burden (per 1,000 persons) of 9.88. To develop preventative and treatment methods for COVID-19-related cardiovascular symptoms, a better understanding of the biologic pathways will be required.
✍
 		35132265
(Nat Med)
PMID
35132265
Date of Publishing: 2022 Feb 7
Title Long-term cardiovascular outcomes of COVID-19
Author(s) nameXie Y, Xu E et al.
Journal Nat Med
Impact factor
22.66
Citation count: 36
Date of Entry 2022 Feb 28

Incidence of post-acute Covid-19 composite of other cardiovascular disorders (heart failure, non-ischemic cardiomyopathy, cardic arrest, cardiogenic shock) had a hazard ratio (HR) of 1.72 and a 1-year burden (per 1,000 people) of 12.72. People who have survived an acute episode of COVID-19 should have their cardiovascular health and illness taken into account in their treatment plans.
✍
 		35132265
(Nat Med)
PMID
35132265
Date of Publishing: 2022 Feb 7
Title Long-term cardiovascular outcomes of COVID-19
Author(s) nameXie Y, Xu E et al.
Journal Nat Med
Impact factor
22.66
Citation count: 36
Date of Entry 2022 Feb 28

Risk of myocarditis and pericarditis without COVID-19 vaccination increased. The demographic composition of our cohort (majority White and male) might limit the generalizability of study findings.
✍
 		35132265
(Nat Med)
PMID
35132265
Date of Publishing: 2022 Feb 7
Title Long-term cardiovascular outcomes of COVID-19
Author(s) nameXie Y, Xu E et al.
Journal Nat Med
Impact factor
22.66
Citation count: 36
Date of Entry 2022 Feb 28

The risks and associated burdens exhibited a graded increase across the severity spectrum of COVID-19 (from non-hospitalized to hospitalised individuals to those admitted to intensive care). Risk of myocarditis and pericarditis without Covid-19 vaccination increased.
✍
 		35132265
(Nat Med)
PMID
35132265
Date of Publishing: 2022 Feb 7
Title Long-term cardiovascular outcomes of COVID-19
Author(s) nameXie Y, Xu E et al.
Journal Nat Med
Impact factor
22.66
Citation count: 36
Date of Entry 2022 Feb 28

Covid-19 is linked to a higher incidence of fatigue, with HRs of 1.81 and 1.87 with contemporary and historical controls, respectively. Influenza vaccination was not shown to be significantly linked to any of the pre-specified cardiovascular outcomes.
✍
 		35132265
(Nat Med)
PMID
35132265
Date of Publishing: 2022 Feb 7
Title Long-term cardiovascular outcomes of COVID-19
Author(s) nameXie Y, Xu E et al.
Journal Nat Med
Impact factor
22.66
Citation count: 36
Date of Entry 2022 Feb 28

Based on the study it was found that risk factors for SARS-COV-2 associated mortality and morbidity irrepective of age, sex are the history of macular degeneration and coagulation disorder. In addition to type-I interferon and interleukin-6-dependent inflammatory responses, infection leads in significant involvement of the complement and coagulation pathways, according to transcriptional profiling of nasopharyngeal swabs.
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 		32747830
(Nat Med)
PMID
32747830
Date of Publishing: 2020 Oct
Title Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection
Author(s) nameRamlall V, Thangaraj PM et al.
Journal Nat Med
Impact factor
22.66
Citation count: 118
Date of Entry 2021 Oct 31

Increased COVID-19 incidence was associated with high concentration of superstores, due to its potential for efficient transmission of SARS-CoV-2. No significant association of COVID-19 cases with population density or age or household income was reported. Owing to its correlation between increase in COVID-19 cases and position of superstores, retailers are warned to implement protective measures early enough to control spread of the disease.
✍
 		33980403
(Spat Spatiotemporal Epidemiol)
PMID
33980403
Date of Publishing: 2021 Jun
Title Socio-spatial influences on the prevalence of COVID-19 in central Pennsylvania
Author(s) nameHenning A, McLaughlin C et al.
Journal Spat Spatiotemporal Epidemiol
Impact factor
1.34
Citation count: 1

Higher risk of contracting SARS-CoV-2 infection was reported in individuals with B+ blood type (36.3%) than those with O+ blood type (29%) and A+ blood type (20.9%). Post-COVID complications such as sleep disturbances, pains, anxiety and depression were also reported. Table showing baseline characteristics of COVID-19 patients Table presenting post-COVID complications in patients
✍
 		33520252
(New Microbes New Infect)
PMID
33520252
Date of Publishing: 2021 Mar
Title A multi-centre, cross-sectional study on coronavirus disease 2019 in Bangladesh: clinical epidemiology and short-term outcomes in recovered individuals
Author(s) nameMannan A, Mehedi HMH et al.
Journal New Microbes New Infect
Impact factor
1.6
Citation count: 12

Risk of prolonged COVID-19 infection was higher in individuals with higher BMI and triglycerides level, since BMI indirectly lowers IgG immune response when triglyceride levels are high. This is also owed to the direct impact of BMI and triglycerides on 7 proteins: CRP, Factor B and H, the interleukin 1 family of proteins, SAA/2, fibrinogen and antithrombin III via separate pathways. Heatmap for protein Quanitative trait loci (pQTL) , Forest plots for Mendelian Randomization Estimates
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 		33548839
(EBioMedicine)
PMID
33548839
Date of Publishing: 2021 Feb
Title Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to severe SARS-CoV-2
Author(s) nameRichardson TG, Fang S et al.
Journal EBioMedicine
Impact factor
6.49
Citation count: 5

Higher risk of SARS-CoV-2 infections was observed in Delivery personnels, Informal traders (Salesman) and Transport sector workers compared to others. Overall COVID-19 Incidence rate was 41%.
✍
 		33434668
(Int J Infect Dis)
PMID
33434668
Date of Publishing: 2021 Jan 9
Title Epidemiology of COVID-19 in Mexico: Symptomatic profiles andpresymptomatic people
Author(s) nameFernández-Rojas MA, Luna-Ruiz Esparza MA et al.
Journal Int J Infect Dis
Impact factor
3.42
Citation count: 11

Risk of COVID-19 incidence decreased due to the implementation of lockdown measures and restricted movement. In addition, negative correlation was observed between temperature, relative humidity and COVID-19 transmission. Graph showing negative correlation of Temperature with Covid cases
✍
 		33495673
(J Clean Prod)
PMID
33495673
Date of Publishing: 2021 Jan 16
Title The Role of Weather Conditions in COVID-19 Transmission: A Study of a Global Panel of 1236 Regions
Author(s) nameZhang C, Liao H et al.
Journal J Clean Prod
Impact factor
15.6
Citation count: 4

Risk of COVID-19 transmission increased in nursing homes due to factors such as reduced staffing levels of total staff members and Licensed Practical Nurses (LPNs) as well as number of fines issued in 2020 because of non-conformity to the pandemic guidelines. Also, county-level factor like per-capita income (RR-1.86) showed a higher association with COVID-19 incidence in nursing homes compared to others. Table for Risk factors at Nursing home and County-level
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 		32889290
(Sci Total Environ)
PMID
32889290
Date of Publishing: 2021 Jan 15
Title Mapping community-level determinants of COVID-19 transmission in nursing homes: A multi-scale approach
Author(s) nameSugg MM, Spaulding TJ et al.
Journal Sci Total Environ
Impact factor
5.9
Citation count: 38

Higher risk of hospitalization due to COVID-19 was reported in a study population with certain risk factors (46%) whereas increased risk of mortality was observed in those with Rheumatoid arthritis or SLE (5%). Graph representing Risk factors for Hospitalization
✍
 		33339986
(Nat Rev Rheumatol)
PMID
33339986
Date of Publishing: 2020 Dec 18
Title Rheumatic disease and COVID-19: epidemiology and outcomes
Author(s) name Hyrich KL, Machado PM.
Journal Nat Rev Rheumatol
Impact factor
16
Citation count: 45

Hypertension (49%) and Diabetes mellitus (47%) were the most common co-morbidities in Mumbai healthcare workers infected with COVID-19.
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 		33247637
(J Assoc Physicians India)
PMID
33247637
Date of Publishing: 2020 Dec
Title Prevalence and Clinical Presentation of COVID-19 among Healthcare Workers at a Dedicated Hospital in India
Author(s) nameMahajan NN, Mathe A et al.
Journal J Assoc Physicians India
Impact factor
0.5
Citation count: 9

Risk of COVID-19 positivity among students with a history of loss of taste and/or smell were 4 times higher than those without symptoms. Similarly, students with confirmed or suspected exposure to a positive COVID-19 case were 3.3 times as likely to test positive. Increased test positivity for those with a history of international travel and domestic travel since December 1, 2019 was also reported.
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 		33071164
(J Adolesc Health)
PMID
33071164
Date of Publishing: 2020 Dec
Title A Cross-Sectional Study Examining the Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies in a University Student Population
Author(s) nameTilley K, Ayvazyan V et al.
Journal J Adolesc Health
Impact factor
6.3
Citation count: 18

Out of 3711 healthcare workers (HCW) including 297 frontline HCW, 116 non-frontline, 113 physicians, 103 nurses and 197 other staff, 413 (11%) were SARS-CoV-2 infected. Frontline workers were highly prone to SARS-CoV-2 due to their close contact with COVID-19 patients. An overall 1% mortality rate was reported. Median age of COVID-19 infected HCWs was 32 years.
✍
 		33247637
(J Assoc Physicians India)
PMID
33247637
Date of Publishing: 2020 Dec
Title Prevalence and Clinical Presentation of COVID-19 among Healthcare Workers at a Dedicated Hospital in India
Author(s) nameMahajan NN, Mathe A et al.
Journal J Assoc Physicians India
Impact factor
0.5
Citation count: 9

Risk of premature (<37 weeks) birth was observed in 12.9% infants born to SARS-CoV-2 infected mothers. Among 610 (21.3%) tested infants, 2.6% were positive for SARS-CoV-2 infection, indicating vertical transmission.
✍
 		33151917
(MMWR Morb Mortal Wkly Rep)
PMID
33151917
Date of Publishing: 2020 Nov 6
Title Birth and Infant Outcomes Following Laboratory-Confirmed Infection in Pregnancy SET-NET, 16 Jurisdictions, March 29October 14, 2020 SARS-CoV-2
Author(s) nameWoodworth KR, Olsen EO et al.
Journal MMWR Morb Mortal Wkly Rep
Impact factor
14.4
Citation count: 126

High risk of contracting SARS-CoV-2 infection from index patients was reported in household members with Asthma (13%) than those with chronic lung or renal disease (1%). Moderate risk of SARS-COV-2 transmission was reported for those with Cardiovascular disease and Diabetes (4%), Immunodeficiency and Smokers (2%) . Median age of index patients was 32 years and that of household members was 28 years.
✍
 		33151916
(MMWR Morb Mortal Wkly Rep)
PMID
33151916
Date of Publishing: 2020 Nov 6
Title Transmission of SARS-COV-2 Infections in Households Tennessee and Wisconsin, April-September 2020
Author(s) nameGrijalva CG, Rolfes MA et al.
Journal MMWR Morb Mortal Wkly Rep
Impact factor
14.4
Citation count: 99

A higher risk of contracting SARS-CoV-2 was observed in Individuals who had obesity (24%), attended large gatherings such as graduation dinner (30%), planting dinner (22%) and visited households (24%) than those with Diabetes mellitus and cardiovascular (10%), chronic lung disease and hyperglycemia (7%), being in the household (14%) or working (4%)
✍
 		33151922
(MMWR Morb Mortal Wkly Rep)
PMID
33151922
Date of Publishing: 2020 Nov 6
Title A SARS-CoV-2 Outbreak Illustrating the Challenges in Limiting the Spread of the Virus - Hopi Tribe, May-June 2020
Author(s) nameHirschman J, Kaur H et al.
Journal MMWR Morb Mortal Wkly Rep
Impact factor
14.4
Citation count: 4

Out of 54 residents in a psychiatric facility, 40 (74%) were infected with SARS-CoV-2 with doubling time of 3.9 days. Obesity as a risk factor (43%) and no other psychiatric or medical condition was significantly associated with the infection.
✍
 		33166098
(Prim Care Companion CNS Disord)
PMID
33166098
Date of Publishing: 2020 Nov 5
Title COVID-19 Transmission in a Psychiatric Long-Term Care Rehabilitation Facility: An Observational Study.
Author(s) nameXiong GL, Atkin A et al.
Journal Prim Care Companion CNS Disord
Impact factor
0.3
Citation count: 1

Positive risk predictors for COVID-19 cases and deaths were wind speed, major sports events, white race ( 0.8, p < 0.05) and GDP per capita ( = 1.07, p = 0.04) whereas negative risk predictor for COVID-19 cases ( = 1.76, p = 6.62 106) and deaths ( = 0.94, p = 0.01) was yellow race. Graphs showing association between risk factors and COVID transmission and fatality
✍
 		33339626
(Public Health)
PMID
33339626
Date of Publishing: 2020 Nov 19
Title Important factors affecting COVID-19 transmission and fatality in metropolises
Author(s) nameCao W, Chen C et al.
Journal Public Health
Impact factor
1.774
Citation count: 5