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A model anti-pandemic portal for scientists & public
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Last updated: 2021 Jul 12
Total hit(s): 6
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Original Article
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Metagenomic sequencing of
RNA
from a single patient in Wuhan led to the identification of a new virus belonging to the Coronaviridae family and designated as 'WH-Human 1' virus.
The longest (30,474 nucleotides) had highest abundance and closely resembled the SARS-like coronavirus (CoV) isolate--bat SL-CoVZC45 (GenBank accession number MG772933) with 89.1% identity.
✍
32015508
(
Nature
)
PMID
32015508
Date of Publishing
: 2020 Mar
Title
A new coronavirus associated with human respiratory disease in China
Author(s) name
Wu F, Zhao S et al.
Journal
Nature
Impact factor
24.36
Citation count
: 4209
Date of Entry
2021 Jul 12
×
NLM format
Wu F, Zhao S, Yu B, Chen YM, Wang W, Song ZG, Hu Y, Tao ZW, Tian JH, Pei YY, Yuan ML, Zhang YL, Dai FH, Liu Y, Wang QM, Zheng JJ, Xu L, Holmes EC, Zhang YZ. A new coronavirus associated with human respiratory disease in China. Nature. 2020 Mar;579(7798):265-269. PMID:32015508
Complete Coding Sequence of surface glycoprotein
(S)
gene, reported from an immunocompromised cancer patient infected with long-term SARS-CoV-2 infection (Pittsburgh long-term infection 1).
The patient was named Pittsburgh long-term infection 1 (PLTI1) because the infection persisted 74 days after the COVID-19 diagnosis.
Two variants with deletions in the NTD of S glycoprotein, were identified.
✍
33536258
(
Science
)
PMID
33536258
Date of Publishing
: 2021 Feb 3
Title
Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape
Author(s) name
McCarthy KR, Rennick LJ et al.
Journal
Science
Impact factor
20.57
Citation count
: 220
×
NLM format
McCarthy KR, Rennick LJ, Nambulli S, Robinson-McCarthy LR, Bain WG, Haidar G, Duprex WP. Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape. Science. 2021 Mar 12;371(6534):1139-1142. PMID:33536258
Metagenomics analysis of three samples from
Taiwan
revealed the co-existence of Haemophilus parainfluenzae.
NGS depths representing exixtence of infections: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473175/bin/TEMI_A_1782271_SM4509.jpg Haemophilus parainfluenzae (accession number CP035368.2) was the dominant population in metagenomic contigs of CGMH-CGU-07 and -08 samples.
✍
32543353
(
Emerg Microbes Infect
)
PMID
32543353
Date of Publishing
: 2020 Dec
Title
SARS-CoV-2 genomic surveillance in Taiwan revealed novel ORF8-deletion mutant and clade possibly associated with infections in Middle East
Author(s) name
Gong YN, Tsao KC et al.
Journal
Emerg Microbes Infect
Impact factor
5.84
Citation count
: 69
×
NLM format
Gong YN, Tsao KC, Hsiao MJ, Huang CG, Huang PN, Huang PW, Lee KM, Liu YC, Yang SL, Kuo RL, Chen KF, Liu YC, Huang SY, Huang HI, Liu MT, Yang JR, Chiu CH, Yang CT, Chen GW, Shih SR. SARS-CoV-2 genomic surveillance in Taiwan revealed novel ORF8-deletion mutant and clade possibly associated with infections in Middle East. Emerg Microbes Infect. 2020 Dec;9(1):1457-1466. PMID:32543353
Metagenomics sequencing revealed bacterial and viral
co-infections
and the respiratory microbial diversity associated with SARS-CoV-2, cause of disease severity.
SARS-CoV-2 was detected in 31/40 (77.5%) samples positive by RT-PCR. No fungal or protist coinfections were detected
✍
33219095
(
mBio
)
PMID
33219095
Date of Publishing
: 2020 Nov 20
Title
Metagenomic Next-Generation Sequencing of Nasopharyngeal Specimens Collected from Confirmed and Suspect COVID-19 Patients
Author(s) name
Mostafa HH, Fissel JA et al.
Journal
mBio
Impact factor
6.5
Citation count
: 39
×
NLM format
Mostafa HH, Fissel JA, Fanelli B, Bergman Y, Gniazdowski V, Dadlani M, Carroll KC, Colwell RR, Simner PJ. Metagenomic Next-Generation Sequencing of Nasopharyngeal Specimens Collected from Confirmed and Suspect COVID-19 Patients. mBio. 2020 Nov 20;11(6):e01969-20. PMID:33219095
Metagenomics analysis of the first SARS-CoV-2 patient from
Ecuador
revealed the presence of pathogenic bacterial
coinfection.
It was most likely involved in worsening the patient's health condition.
The Age of patient 50 years, gender: male, Number of DNA sequences were: 206111 Number of Bases: 43603091 Coronavirus sequences represented 0.036%, Of all microorganisms presents.
✍
32588004
(
medRxiv
)
PMID
32588004
Date of Publishing
: 2020 Jun 14
Title
Genome sequencing of the first SARS-CoV-2 reported from patients with COVID-19 in Ecuador
Author(s) name
Marquez S, Prado-Vivar B et al.
Journal
medRxiv
Impact factor
- n/a -
Citation count
: 1
×
NLM format
Marquez S, Prado-Vivar B, Guadalupe JJ, Gutierrez Granja B, Jibaja M, Tobar M, Mora F, Gaviria J, Garcia M, Ligna E, Espinosa F, Reyes J, Barragan V, Rojas-Silva P, Trueba G, Grunauer M, Cardenas P. Genome sequencing of the first SARS-CoV-2 reported from patients with COVID-19 in Ecuador. medRxiv. 2020 Jun 14:2020.06.11.20128330. PMID:32588004
Metagenomic Analysis of a Sample (WIV04) from Wuhan,
China,
revealed a new coronavirus (2019-nCoV). It caused an epidemic of acute respiratory syndrome in humans.
Of the obtained total reads (10,038,758), 1,582 reads were retained after removing the reads from the human genome. Of which, 1,378 (87.1%) sequences matched the sequence of SARSr-CoV
✍
32015507
(
Nature
)
PMID
32015507
Date of Publishing
: 2020 Mar
Title
A pneumonia outbreak associated with a new coronavirus of probable bat origin
Author(s) name
Zhou P, Yang XL et al.
Journal
Nature
Impact factor
24.36
Citation count
: 8438
×
NLM format
Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, Si HR, Zhu Y, Li B, Huang CL, Chen HD, Chen J, Luo Y, Guo H, Jiang RD, Liu MQ, Chen Y, Shen XR, Wang X, Zheng XS, Zhao K, Chen QJ, Deng F, Liu LL, Yan B, Zhan FX, Wang YY, Xiao GF, Shi ZL. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020 Mar;579(7798):270-273. PMID:32015507