| | Reporting an amplification-free, fluorescence-based diagnostic method, namely Hybrid Capture Fluorescence Immunoassay (HC-FIA), for diagnosing SARS-CoV-2. It is carried on a lateral flow strip and targets ORF1ab, E, and the N regions of the genome to detect SARS-CoV-2. The assay resulted in 100% and 99% sensitivities and specificities, respectively. | This assay is based on the capture of RNA-DNA hybrids and on immunofluorescence analysis.
The SARS-CoV-2 HC-FIA detection system Fig.1 (https://www.nature.com/articles/s41551-020-00655-z#Fig1) ✍ | 33273714
(Nat Biomed Eng)
| PMID | 33273714 Date of Publishing: 2020 Dec | | Title | Rapid lateral flow immunoassay for the fluorescence detection of SARS-CoV-2 RNA | | Author(s) name | Wang D, He S et al. | | Journal | Nat Biomed Eng | | Impact factor | 31.8 Citation count: 49 |
×
| NLM format |
| Wang D, He S, Wang X, Yan Y, Liu J, Wu S, Liu S, Lei Y, Chen M, Li L, Zhang J, Zhang L, Hu X, Zheng X, Bai J, Zhang Y, Zhang Y, Song M, Tang Y. Rapid lateral flow immunoassay for the fluorescence detection of SARS-CoV-2 RNA. Nat Biomed Eng. 2020 Dec;4(12):1150-1158. PMID:33273714 |
|