| Whole-genome sequencing for 2 S gene target failure (SGTF) samples showed that the S deletion 21765-21770 was present in 100% of the reads. It also leads to the removal of 2 amino acids (H69/V70) in the N-terminal domain of the S1 subunit of the S protein. | ✍ | 33478625 (Euro Surveill)
PMID | 33478625 Date of Publishing: 2021 Jan | Title | Two-step strategy for the identification of SARS-CoV-2 variant of concern 202012/01 and other variants with spike deletion H69V70, France, August to December 2020 | Author(s) name | Bal A, Destras G et al. | Journal | Euro Surveill | Impact factor | 7.37 Citation count: 90 | Date of Entry | 2021 Aug 6 |
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Bal A, Destras G, Gaymard A, Stefic K, Marlet J, Eymieux S, Regue H, Semanas Q, d'Aubarede C, Billaud G, Laurent F, Gonzalez C, Mekki Y, Valette M, Bouscambert M, Gaudy-Graffin C, Lina B, Morfin F, Josset L; COVID-Diagnosis HCL Study Group. Two-step strategy for the identification of SARS-CoV-2 variant of concern 202012/01 and other variants with spike deletion H69V70, France, August to December 2020. Euro Surveill. 2021 Jan;26(3):2100008. PMID:33478625 |
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