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Antibody
Last updated: 2022 Feb 19
Total hit(s): 46
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Original Article
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Neutralizing activity of
Bamlanivimab,
Etesevimab,
REGN10933 (casirivimab), REGN10987 (imdevimab), C102, P2B-2F6, and Fab2-36 monoclonal
antibodies
against SARS-CoV-2
Omicron
variant showed a IC
50
of >10 µg ml
-1
.
Sotrovimab
(S309) and DZIF-10c had a neutralizing IC
50
of 0.0950 and 0.0346 µg ml
-1
, respectively.
Several monoclonal antibodies' neutralising efficacy against the Omicron variant is significantly reduced, and this may limit therapy choices for Omicron-induced COVID-19.
✍
35046572
(
Nat Med
)
PMID
35046572
Date of Publishing
: 2022 Jan 19
Title
mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant
Author(s) name
Gruell H, Vanshylla K et al.
Journal
Nat Med
Impact factor
22.66
Citation count
: 59
Date of Entry
2022 Feb 19
×
NLM format
Gruell H, Vanshylla K, Tober-Lau P, Hillus D, Schommers P, Lehmann C, Kurth F, Sander LE, Klein F. mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant. Nat Med. 2022 Jan 19:1-4. PMID:35046572
In convalescent patients, more than 80% of the anti-spike IgG
antibody
response is directed against epitopes outside the receptor
binding
domain (RBD). In one patient,
antibodies
were aimed at the amino
(N)
-terminal domain (NTD) that proved protective against a deadly viral attack.
In a high viral load test, a cocktail of the top non-RBD plasma mAbs CM29CM31 (>85% of the IgG plasma lineages to S-ECD) provided the most effective protection and lung viral titers below the limit of detection (LOD) (10^4 PFU).
✍
33947773
(
Science
)
PMID
33947773
Date of Publishing
: 2021 May 4
Title
Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes
Author(s) name
Voss WN, Hou YJ et al.
Journal
Science
Impact factor
20.57
Citation count
: 83
Date of Entry
2021 Oct 31
×
NLM format
Voss WN, Hou YJ, Johnson NV, Delidakis G, Kim JE, Javanmardi K, Horton AP, Bartzoka F, Paresi CJ, Tanno Y, Chou CW, Abbasi SA, Pickens W, George K, Boutz DR, Towers DM, McDaniel JR, Billick D, Goike J, Rowe L, Batra D, Pohl J, Lee J, Gangappa S, Sambhara S, Gadush M, Wang N, Person MD, Iverson BL, Gollihar JD, Dye JM, Herbert AS, Finkelstein IJ, Baric RS, McLellan JS, Georgiou G, Lavinder JJ, Ippolito GC. Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes. Science. 2021 Jun 4;372(6546):1108-1112. PMID:33947773
3 Monoclonal
antibodies
(mAb#1, mAb#2, mAb#3) were raised against the NRP1 b1b2 ectodomain to establish functional relevance of S1 CendR-NRP1 interaction. NRP1 enhances the infectivity of SARS-CoV-2 by S1 interaction and also a CendR independent mechanism. mAb1 and mAb3 can control SARS-CoV-2 infections to a large extent.
Small molecule EG00229 inhibits the direct binding of b1 with S1 CendR peptide
✍
33082294
(
Science
)
PMID
33082294
Date of Publishing
: 2020 Nov 13
Title
Neuropilin-1 is a host factor for SARS-CoV-2 infection
Author(s) name
Daly JL, Simonetti B et al.
Journal
Science
Impact factor
20.57
Citation count
: 477
Date of Entry
2021 Aug 2
×
NLM format
Daly JL, Simonetti B, Klein K, Chen KE, Williamson MK, Antón-Plágaro C, Shoemark DK, Simón-Gracia L, Bauer M, Hollandi R, Greber UF, Horvath P, Sessions RB, Helenius A, Hiscox JA, Teesalu T, Matthews DA, Davidson AD, Collins BM, Cullen PJ, Yamauchi Y. Neuropilin-1 is a host factor for SARS-CoV-2 infection. Science. 2020 Nov 13;370(6518):861-865. PMID:33082294
Neutralizing
antibodies
coupled on the photothermal nanoparticle helps in inactivation of virus by preventing the entry of virus into ACE-2 expressing host cell.
Toxicity was not observed.
✍
33269351
(
bioRxiv
)
PMID
33269351
Date of Publishing
: 2020 Nov 30
Title
A Neutralizing Antibody-Conjugated Photothermal Nanoparticle Captures and Inactivates SARS-CoV-2
Author(s) name
Cai X, Prominski A et al.
Journal
bioRxiv
Impact factor
- n/a -
Citation count
: 9
×
NLM format
Cai X, Prominski A, Lin Y, Ankenbruck N, Rosenberg J, Chen M, Shi J, Chang EB, Penaloza-MacMaster P, Tian B, Huang J. A Neutralizing Antibody-Conjugated Photothermal Nanoparticle Captures and Inactivates SARS-CoV-2. bioRxiv. 2020 Nov 30:2020.11.30.404624. PMID:33269351
The neutralizing potential efficiency of anti-Spike-S1 IgYs (chicken egg yolk
antibodies)
that blocks the
binding
of various variants of SARS-CoV-2
spike protein
to ACE-2 receptor was researched.
✍
33191178
(
Int Immunopharmacol
)
PMID
33191178
Date of Publishing
: 2020 Nov 3
Title
Chicken Egg Yolk Antibodies (IgYs) block the binding of multiple SARS-CoV-2 spike protein variants to human ACE2
Author(s) name
Wei S, Duan S et al.
Journal
Int Immunopharmacol
Impact factor
3.38
Citation count
: 6
×
NLM format
Wei S, Duan S, Liu X, Wang H, Ding S, Chen Y, Xie J, Tian J, Yu N, Ge P, Zhang X, Chen X, Li Y, Meng Q. Chicken Egg Yolk Antibodies (IgYs) block the binding of multiple SARS-CoV-2 spike protein variants to human ACE2. Int Immunopharmacol. 2021 Jan;90:107172. PMID:33191178
REGN-COV2
antibodies
are efficacious when used prophylactically or therapeutically. This mAB cocktail could reduce the viral load and also decrease virus-induced pathological sequelae in rhesus macaque and limit weight loss in hamsters.
✍
33037066
(
Science
)
PMID
33037066
Date of Publishing
: 2020 Nov 27
Title
REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters.
Author(s) name
Baum A, Ajithdoss D et al.
Journal
Science
Impact factor
20.57
Citation count
: 245
×
NLM format
Baum A, Ajithdoss D, Copin R, Zhou A, Lanza K, Negron N, Ni M, Wei Y, Mohammadi K, Musser B, Atwal GS, Oyejide A, Goez-Gazi Y, Dutton J, Clemmons E, Staples HM, Bartley C, Klaffke B, Alfson K, Gazi M, Gonzalez O, Dick E Jr, Carrion R Jr, Pessaint L, Porto M, Cook A, Brown R, Ali V, Greenhouse J, Taylor T, Andersen H, Lewis MG, Stahl N, Murphy AJ, Yancopoulos GD, Kyratsous CA. REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters.. Science. 2020 Nov 27;370(6520):1110-1115. PMID:33037066
4A8 monoclonal
antibody
shows a high affinity to bind to the polybasic insert at the furin-like cleavage site.
1.) in silico screening of SARS-CoV-2 neutralizing mAbs: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709177/table/T1/ and 2.) Supplementary data: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709177/#SD1
✍
33269352
(
bioRxiv
)
PMID
33269352
Date of Publishing
: 2020 Nov 24
Title
A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro
Author(s) name
Cheng MH, Porritt RA et al.
Journal
bioRxiv
Impact factor
- n/a -
Citation count
: 3
×
NLM format
Cheng MH, Porritt RA, Rivas MN, Krieger JM, Ozdemir AB, Garcia G Jr, Arumugaswami V, Fries BC, Arditi M, Bahar I. A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro. bioRxiv. 2020 Nov 24:2020.11.24.395079. PMID:33269352
6D3 monoclonal
antibody
can block the SARS-CoV infection by inhibiting the access of host cell proteases,
TMPRSS2
or furin.
Figures: 1.)Binding poses: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709177/figure/F2/ 2.) 4A8 binding characteristics examination: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709177/figure/F3/ 3.) 6D3 inhibiting SARS-CoV-2 data: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709177/figure/F5/ 4.) Polyacidic residues in the CDR2 of 6D3 and 4A8 heavy chains: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709177/figure/F6/
✍
33269352
(
bioRxiv
)
PMID
33269352
Date of Publishing
: 2020 Nov 24
Title
A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro
Author(s) name
Cheng MH, Porritt RA et al.
Journal
bioRxiv
Impact factor
- n/a -
Citation count
: 3
×
NLM format
Cheng MH, Porritt RA, Rivas MN, Krieger JM, Ozdemir AB, Garcia G Jr, Arumugaswami V, Fries BC, Arditi M, Bahar I. A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro. bioRxiv. 2020 Nov 24:2020.11.24.395079. PMID:33269352
A monoclonal
Antibody
(2B04) potently inhibited SARS-CoV-2 infection with an IC50 of 3.007 ng/mL.
✍
33035201
(
JCI Insight
)
PMID
33035201
Date of Publishing
: 2020 Nov 19
Title
Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers and convalescent plasma donors.
Author(s) name
Zeng C, Evans JP et al.
Journal
JCI Insight
Impact factor
6.014
Citation count
: 35
×
NLM format
Zeng C, Evans JP, Pearson R, Qu P, Zheng YM, Robinson RT, Hall-Stoodley L, Yount J, Pannu S, Mallampalli RK, Saif L, Oltz E, Lozanski G, Liu SL. Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers and convalescent plasma donors.. JCI Insight. 2020 Nov 19;5(22):e143213. PMID:33035201
Of the 35
monoclonal
anti-bodies 'isolate', mAb 4A8 displayed high neutralizing activity against both the authentic and pseudotyped SARS-CoV2.
✍
32571838
(
Science
)
PMID
32571838
Date of Publishing
: 2020 Aug 7
Title
A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2
Author(s) name
Chi X, Yan R et al.
Journal
Science
Impact factor
20.57
Citation count
: 644
×
NLM format
Chi X, Yan R, Zhang J, Zhang G, Zhang Y, Hao M, Zhang Z, Fan P, Dong Y, Yang Y, Chen Z, Guo Y, Zhang J, Li Y, Song X, Chen Y, Xia L, Fu L, Hou L, Xu J, Yu C, Li J, Zhou Q, Chen W. A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2. Science. 2020 Aug 7;369(6504):650-655. PMID:32571838
Of the 35
monoclonal
anti-bodies isolate, mAb IM-ID2 displayed high neutralizing activity against live SARS-CoV2.
✍
32571838
(
Science
)
PMID
32571838
Date of Publishing
: 2020 Aug 7
Title
A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-3
Author(s) name
Chi X, Yan R et al.
Journal
Science
Impact factor
20.57
Citation count
: 644
×
NLM format
Chi X, Yan R, Zhang J, Zhang G, Zhang Y, Hao M, Zhang Z, Fan P, Dong Y, Yang Y, Chen Z, Guo Y, Zhang J, Li Y, Song X, Chen Y, Xia L, Fu L, Hou L, Xu J, Yu C, Li J, Zhou Q, Chen W. A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-3. Science. 2020 Aug 7;369(6504):650-655. PMID:32571838
Of the 35
monoclonal
anti-bodies 'isolate', mAb 0304-3H3 displayed high neutralizing activity against live SARS-CoV2.
✍
32571838
(
Science
)
PMID
32571838
Date of Publishing
: 2020 Aug 7
Title
A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-4
Author(s) name
Chi X, Yan R et al.
Journal
Science
Impact factor
20.57
Citation count
: 644
×
NLM format
Chi X, Yan R, Zhang J, Zhang G, Zhang Y, Hao M, Zhang Z, Fan P, Dong Y, Yang Y, Chen Z, Guo Y, Zhang J, Li Y, Song X, Chen Y, Xia L, Fu L, Hou L, Xu J, Yu C, Li J, Zhou Q, Chen W. A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-4. Science. 2020 Aug 7;369(6504):650-655. PMID:32571838
Monoclonal
antibody
MD65 showed neutralizing activity in the plaque reduction neutralization test (PRNT) using VeroE6 cells infected with the pathogenic SARS-CoV-2.
Monoclonal antibody MD65 inhibits the binding of RBD to human ACE2
✍
32855401
(
Nat Commun
)
PMID
32855401
Date of Publishing
: 2020 Aug 27
Title
A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
Author(s) name
Noy-Porat T, Makdasi E et al.
Journal
Nat Commun
Impact factor
11.8
Citation count
: 87
×
NLM format
Noy-Porat T, Makdasi E, Alcalay R, Mechaly A, Levy Y, Bercovich-Kinori A, Zauberman A, Tamir H, Yahalom-Ronen Y, Israeli M, Epstein E, Achdout H, Melamed S, Chitlaru T, Weiss S, Peretz E, Rosen O, Paran N, Yitzhaki S, Shapira SC, Israely T, Mazor O, Rosenfeld R. A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes. Nat Commun. 2020 Aug 27;11(1):4303. PMID:32855401
Monoclonal
antibody
MD45 showed neutralizing activity in the plaque reduction neutralization test (PRNT) using VeroE6 cells infected with the pathogenic SARS-CoV-2.
✍
32855401
(
Nat Commun
)
PMID
32855401
Date of Publishing
: 2020 Aug 27
Title
A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
Author(s) name
Noy-Porat T, Makdasi E et al.
Journal
Nat Commun
Impact factor
11.8
Citation count
: 87
×
NLM format
Noy-Porat T, Makdasi E, Alcalay R, Mechaly A, Levy Y, Bercovich-Kinori A, Zauberman A, Tamir H, Yahalom-Ronen Y, Israeli M, Epstein E, Achdout H, Melamed S, Chitlaru T, Weiss S, Peretz E, Rosen O, Paran N, Yitzhaki S, Shapira SC, Israely T, Mazor O, Rosenfeld R. A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes. Nat Commun. 2020 Aug 27;11(1):4303. PMID:32855401
Monoclonal
antibody
MD67 showed neutralizing activity in the plaque reduction neutralization test (PRNT) using VeroE6 cells infected with the pathogenic SARS-CoV-2.
✍
32855401
(
Nat Commun
)
PMID
32855401
Date of Publishing
: 2020 Aug 27
Title
A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
Author(s) name
Noy-Porat T, Makdasi E et al.
Journal
Nat Commun
Impact factor
11.8
Citation count
: 87
×
NLM format
Noy-Porat T, Makdasi E, Alcalay R, Mechaly A, Levy Y, Bercovich-Kinori A, Zauberman A, Tamir H, Yahalom-Ronen Y, Israeli M, Epstein E, Achdout H, Melamed S, Chitlaru T, Weiss S, Peretz E, Rosen O, Paran N, Yitzhaki S, Shapira SC, Israely T, Mazor O, Rosenfeld R. A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes. Nat Commun. 2020 Aug 27;11(1):4303. PMID:32855401
Monoclonal
antibody
MD62 showed neutralizing activity in the plaque reduction neutralization test (PRNT) using VeroE6 cells infected with the pathogenic SARS-CoV-2.
Monoclonal antibody MD62 inhibits the binding of RBD to human ACE2
✍
32855401
(
Nat Commun
)
PMID
32855401
Date of Publishing
: 2020 Aug 27
Title
A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
Author(s) name
Noy-Porat T, Makdasi E et al.
Journal
Nat Commun
Impact factor
11.8
Citation count
: 87
×
NLM format
Noy-Porat T, Makdasi E, Alcalay R, Mechaly A, Levy Y, Bercovich-Kinori A, Zauberman A, Tamir H, Yahalom-Ronen Y, Israeli M, Epstein E, Achdout H, Melamed S, Chitlaru T, Weiss S, Peretz E, Rosen O, Paran N, Yitzhaki S, Shapira SC, Israely T, Mazor O, Rosenfeld R. A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes. Nat Commun. 2020 Aug 27;11(1):4303. PMID:32855401
Monoclonal
antibody
MD63 did not show neutralizing activity in the plaque reduction neutralization test (PRNT) using VeroE6 cells infected with the pathogenic SARS-CoV-2.
✍
32855401
(
Nat Commun
)
PMID
32855401
Date of Publishing
: 2020 Aug 27
Title
A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
Author(s) name
Noy-Porat T, Makdasi E et al.
Journal
Nat Commun
Impact factor
11.8
Citation count
: 87
×
NLM format
Noy-Porat T, Makdasi E, Alcalay R, Mechaly A, Levy Y, Bercovich-Kinori A, Zauberman A, Tamir H, Yahalom-Ronen Y, Israeli M, Epstein E, Achdout H, Melamed S, Chitlaru T, Weiss S, Peretz E, Rosen O, Paran N, Yitzhaki S, Shapira SC, Israely T, Mazor O, Rosenfeld R. A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes. Nat Commun. 2020 Aug 27;11(1):4303. PMID:32855401
Monoclonal
antibody
MD29 showed neutralizing activity in the plaque reduction neutralization test (PRNT) using VeroE6 cells infected with the pathogenic SARS-CoV-2.
Monoclonal antibody MD29 which recognizes the same epitope as antibody CR3022 does not inhibit the binding of RBD to human ACE2
✍
32855401
(
Nat Commun
)
PMID
32855401
Date of Publishing
: 2020 Aug 27
Title
A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
Author(s) name
Noy-Porat T, Makdasi E et al.
Journal
Nat Commun
Impact factor
11.8
Citation count
: 87
×
NLM format
Noy-Porat T, Makdasi E, Alcalay R, Mechaly A, Levy Y, Bercovich-Kinori A, Zauberman A, Tamir H, Yahalom-Ronen Y, Israeli M, Epstein E, Achdout H, Melamed S, Chitlaru T, Weiss S, Peretz E, Rosen O, Paran N, Yitzhaki S, Shapira SC, Israely T, Mazor O, Rosenfeld R. A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes. Nat Commun. 2020 Aug 27;11(1):4303. PMID:32855401
Monoclonal
antibody
MD17 showed a poor neutralizing activity (NT50) in the plaque reduction neutralization test (PRNT) using VeroE6 cells infected with the pathogenic SARS-CoV-2.
✍
32855401
(
Nat Commun
)
PMID
32855401
Date of Publishing
: 2020 Aug 27
Title
A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
Author(s) name
Noy-Porat T, Makdasi E et al.
Journal
Nat Commun
Impact factor
11.8
Citation count
: 87
×
NLM format
Noy-Porat T, Makdasi E, Alcalay R, Mechaly A, Levy Y, Bercovich-Kinori A, Zauberman A, Tamir H, Yahalom-Ronen Y, Israeli M, Epstein E, Achdout H, Melamed S, Chitlaru T, Weiss S, Peretz E, Rosen O, Paran N, Yitzhaki S, Shapira SC, Israely T, Mazor O, Rosenfeld R. A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes. Nat Commun. 2020 Aug 27;11(1):4303. PMID:32855401
A monoclonal
antibody
(CC12.1) neutralized SARS-CoV-2 in vitro and provided full protection against SARS-CoV-2 infection in Syrian hamsters at a
serum
concentration of ~22 μg/ml.
✍
32540903
(
Science
)
PMID
32540903
Date of Publishing
: 2020 Aug 21
Title
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
Author(s) name
Rogers TF, Zhao F et al.
Journal
Science
Impact factor
20.57
Citation count
: 708
×
NLM format
Rogers TF, Zhao F, Huang D, Beutler N, Burns A, He WT, Limbo O, Smith C, Song G, Woehl J, Yang L, Abbott RK, Callaghan S, Garcia E, Hurtado J, Parren M, Peng L, Ramirez S, Ricketts J, Ricciardi MJ, Rawlings SA, Wu NC, Yuan M, Smith DM, Nemazee D, Teijaro JR, Voss JE, Wilson IA, Andrabi R, Briney B, Landais E, Sok D, Jardine JG, Burton DR. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model. Science. 2020 Aug 21;369(6506):956-963. PMID:32540903
A monoclonal
antibody
(CC12.23) neutralized SARS-CoV-2 in vitro and did not protect against SARS-CoV-2 infection in Syrian hamsters at any concentration.
✍
32540903
(
Science
)
PMID
32540903
Date of Publishing
: 2020 Aug 21
Title
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
Author(s) name
Rogers TF, Zhao F et al.
Journal
Science
Impact factor
20.57
Citation count
: 708
×
NLM format
Rogers TF, Zhao F, Huang D, Beutler N, Burns A, He WT, Limbo O, Smith C, Song G, Woehl J, Yang L, Abbott RK, Callaghan S, Garcia E, Hurtado J, Parren M, Peng L, Ramirez S, Ricketts J, Ricciardi MJ, Rawlings SA, Wu NC, Yuan M, Smith DM, Nemazee D, Teijaro JR, Voss JE, Wilson IA, Andrabi R, Briney B, Landais E, Sok D, Jardine JG, Burton DR. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model. Science. 2020 Aug 21;369(6506):956-963. PMID:32540903
The P2C-1A3
antibody
was found to be the most potent in neutralization of pseudoviruses bearing SARS-CoV-2
spike protein
or live SARS-CoV-2.
✍
32454513
(
Nature
)
PMID
32454513
Date of Publishing
: 2020 Aug
Title
Human neutralizing antibodies elicited by SARS-CoV-2 infection
Author(s) name
Ju B, Zhang Q et al.
Journal
Nature
Impact factor
24.36
Citation count
: 847
×
NLM format
Ju B, Zhang Q, Ge J, Wang R, Sun J, Ge X, Yu J, Shan S, Zhou B, Song S, Tang X, Yu J, Lan J, Yuan J, Wang H, Zhao J, Zhang S, Wang Y, Shi X, Liu L, Zhao J, Wang X, Zhang Z, Zhang L. Human neutralizing antibodies elicited by SARS-CoV-2 infection. Nature. 2020 Aug;584(7819):115-119. PMID:32454513
The P2B-2F6
antibody
was found to be the most potent in neutralization of pseudoviruses bearing SARS-CoV-2
spike protein
or live SARS-CoV-2.
✍
32454513
(
Nature
)
PMID
32454513
Date of Publishing
: 2020 Aug
Title
Human neutralizing antibodies elicited by SARS-CoV-2 infection
Author(s) name
Ju B, Zhang Q et al.
Journal
Nature
Impact factor
24.36
Citation count
: 847
×
NLM format
Ju B, Zhang Q, Ge J, Wang R, Sun J, Ge X, Yu J, Shan S, Zhou B, Song S, Tang X, Yu J, Lan J, Yuan J, Wang H, Zhao J, Zhang S, Wang Y, Shi X, Liu L, Zhao J, Wang X, Zhang Z, Zhang L. Human neutralizing antibodies elicited by SARS-CoV-2 infection. Nature. 2020 Aug;584(7819):115-119. PMID:32454513
The P2C-1F11
antibody
was found to be the most potent in the neutralization of pseudoviruses bearing SARS-CoV-2
spike protein
or live SARS-CoV-2.
✍
32454513
(
Nature
)
PMID
32454513
Date of Publishing
: 2020 Aug
Title
Human neutralizing antibodies elicited by SARS-CoV-2 infection
Author(s) name
Ju B, Zhang Q et al.
Journal
Nature
Impact factor
24.36
Citation count
: 847
×
NLM format
Ju B, Zhang Q, Ge J, Wang R, Sun J, Ge X, Yu J, Shan S, Zhou B, Song S, Tang X, Yu J, Lan J, Yuan J, Wang H, Zhao J, Zhang S, Wang Y, Shi X, Liu L, Zhao J, Wang X, Zhang Z, Zhang L. Human neutralizing antibodies elicited by SARS-CoV-2 infection. Nature. 2020 Aug;584(7819):115-119. PMID:32454513
A monoclonal
antibody
(COV2-2381) protected rhesus macaques against SARS-CoV-2 infection.
✍
32668443
(
Nature
)
PMID
32668443
Date of Publishing
: 2020 Aug
Title
Potently neutralizing and protective human antibodies against SARS-CoV-2
Author(s) name
Zost SJ, Gilchuk P et al.
Journal
Nature
Impact factor
24.36
Citation count
: 460
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NLM format
Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Shrihari S, Mueller BK, Meiler J, Chandrashekar A, Mercado NB, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, McCune BT, Keeler SP, Holtzman MJ, Barouch DH, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr. Potently neutralizing and protective human antibodies against SARS-CoV-2. Nature. 2020 Aug;584(7821):443-449. PMID:32668443