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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Protein information for KMT2C (Homo sapiens) (Information is obtained from UniProt database)

UniProt ID Q6N019 Size Length:116 AA   Molecular weight:13503 Sequence >SQ SEQUENCE 116 AA; 13503 MW; 34F1E198AA19220E CRC64; MVIEYIGTII RNEVANRKEK LYESQNRGVY MFRMDNDHVI DATLTGGPAR YINHSCAPNC VAEVVTFERG HKIIISSSRR IQKGEELCYD YKFDFEDDQH KIPCHCGAVN CRKWMN UniProt ID Q75MN6 Size Length:2185 AA   Molecular weight:239414 Sequence >SQ SEQUENCE 2185 AA; 239414 MW; 73A98266F335817E CRC64; MHNTVVLFSS SDKFTLNQDM CVVCGSFGQG AEGRLLACSQ CGQCYHPYCV SIKITKVVLS KGWRCLECTV CEACGKATDP GRLLLCDDCD ISYHTYCLDP PLQTVPKGGW KCKWCVWCRH CGATSAGLRC EWQNNYTQCA PCASLSSCPV CYRNYREEDL ILQCRQCDRW MHAVCQNLNT EEEVENVADI GFDCSMCRPY MPASNVPSSD CCESSLVAQI VTKVKELDPP KTYTQDGVCL TESGMTQLQS LTVTVPRRKR SKPKLKLKII NQNSVAVLQT PPDIQSEHSR DGEMDDSREG ELMDCDGKSE SSPEREAVDD ETKGVEGTDG VKKRKRKPYR PGIGGFMVRQ RSRTGQGKTK RSVIRKDSSG SISEQLPCRD DGWSEQLPDT LVDESVSVTE STEKIKKRYR KRKNKLEETF PAYLQEAFFG KDLLDTSRQS KISLDNLSED GAQLLYKTNM NTGFLDPSLD PLLSSSSAPT KSGTHGPADD PLADISEVLN TDDDILGIIS DDLAKSVDHS DIGPVTDDPS SLPQPNVNQS SRPLSEEQLD GILSPELDKM VTDGAILGKL YKIPELGGKD VEDLFTAVLS PANTQPTPLP QPPPPTQLLP IHNQDAFSRM PLMNGLIGSS PHLPHNSLPP GSGLGTFSAI AQSSYPDARD KNSAFNPMAS DPNNSWTSSA PTVEGENDTM SNAQRSTLKW EKEEALGEMA TVAPVLYTNI NFPNLKEEFP DWTTRVKQIA KLWRKASSQE RAPYVQKARD NRAALRINKV QMSNDSMKRQ QQQDSIDPSS RIDSELFKDP LKQRESEHEQ EWKFRQQMRQ KSKQQAKIEA TQKLEQVKNE QQQQQQQQFG SQHLLVQSGS DTPSSGIQSP LTPQPGNGNM SPAQSFHKEL FTKQPPSTPT STSSDDVFVK PQAPPPPPAP SRIPIQDSLS QAQTSQPPSP QVFSPGSSNS RPPSPMDPYA KMVGTPRPPP VGHSFSRRNS AAPVENCTPL SSVSRPLQMN ETTANRPSPV RDLCSSSTTN NDPYAKPPDT PRPVMTDQFP KSLGLSRSPV VSEQTAKGPI AAGTSDHFTK PSPRADVFQR QRIPDSYARP LLTPAPLDSG PGPFKTPMQP PPSSQDPYGS VSQASRRLSV DPYERPALTP RPIDNFSHNQ SNDPYSQPPL TPHPAVNESF AHPSRAFSQP GTISRPTSQD PYSQPPGTPR PVVDSYSQSS GTARSNTDPY SQPPGTPRPT TVDPYSQQPQ TPRPSTQTDL FVTPVTNQRH SDPYAHPPGT PRPGISVPYS QPPATPRPRI SEGFTRSSMT RPVLMPNQDP FLQAAQNRGP ALPGPLVRPP DTCSQTPRPP GPGLSDTFSR VSPSAARDPY DQSPMTPRSQ SDSFGTSQTA HDVADQPRPG SEGSFCASSN SPMHSQGQQF SGVSQLPGPV PTSGVTDTQN TVNMAQADTE KLRQRQKLRE IILQQQQQKK IAGRQEKGSQ DSPAVPHPGP LQHWQPENVN QAFTRPPPPY PGNIRSPVAP PLGPRYAVFP KDQRGPYPPD VASMGMRPHG FRFGFPGGSH GTMPSQERFL VPPQQIQGSG VSPQLRRSVS VDMPRPLNNS QMNNPVGLPQ HFSPQSLPVQ QHNILGQAYI ELRHRAPDGR QRLPFSAPPG SVVEASSNLR HGNFIPRPDF PGPRHTDPMR RPPQGLPNQL PVHPDLEQVP PSQQEQGHSV HSSSMVMRTL NHPLGGEFSE APLSTSVPSE TTSDNLQITT QPSDGLEEKL DSDDPSVKEL DVKDLEGVEV KDLDDEDLEN LNLDTEDGKV VELDTLDNLE TNDPNLDDLL RSGEFDIIAY TDPELDMGDK KSMFNEELDL PIDDKLDNQC VSVEPKKKEQ ENKTLVLSDK HSPQKKSTVT NEVKTEVLSP NSKVESKCET EKNDENKDNV DTPCSQASAH SDLNDGEKTS LHPCDPDLFE KRTNRETAGP SANVIQASTQ LPAQDVINSC GITGSTPVLS SLLANEKSDN SDIRPSGSPP PPTLPASPSN HVSSLPPFIA PPGRVLDNAM NSNVTVVSRV NHVFSQGVQV NPGLIPGQST VNHSLGTGKP ATQTGPQTSQ SGTSSMSGPQ QLMIPQTLAQ QNRERPLLLE EQPLLLQDLL DQERQEQQQQ RQMQAMIRQR SEPFFPNIDF DAITDPIMKA KMVALKGINK VMAQNNLGMP PMVMS UniProt ID Q8NEZ4 Protein name Histone-lysine N-methyltransferase MLL3 Size Length:4911 AA   Molecular weight:541370 Sequence >SQ SEQUENCE 4911 AA; 541370 MW; 898CEE324772BD75 CRC64; MSSEEDKSVE QPQPPPPPPE EPGAPAPSPA AADKRPRGRP RKDGASPFQR ARKKPRSRGK TAVEDEDSMD GLETTETETI VETEIKEQSA EEDAEAEVDN SKQLIPTLQR SVSEESANSL VSVGVEAKIS EQLCAFCYCG EKSSLGQGDL KQFRITPGFI LPWRNQPSNK KDIDDNSNGT YEKMQNSAPR KQRGQRKERS PQQNIVSCVS VSTQTASDDQ AGKLWDELSL VGLPDAIDIQ ALFDSTGTCW AHHRCVEWSL GVCQMEEPLL VNVDKAVVSG STERCAFCKH LGATIKCCEE KCTQMYHYPC AAGAGTFQDF SHIFLLCPEH IDQAPERSKE DANCAVCDSP GDLLDQFFCT TCGQHYHGMC LDIAVTPLKR AGWQCPECKV CQNCKQSGED SKMLVCDTCD KGYHTFCLQP VMKSVPTNGW KCKNCRICIE CGTRSSSQWH HNCLICDNCY QQQDNLCPFC GKCYHPELQK DMLHCNMCKR WVHLECDKPT DHELDTQLKE EYICMYCKHL GAEMDRLQPG EEVEIAELTT DYNNEMEVEG PEDQMVFSEQ AANKDVNGQE STPGIVPDAV QVHTEEQQKS HPSESLDTDS LLIAVSSQHT VNTELEKQIS NEVDSEDLKM SSEVKHICGE DQIEDKMEVT ENIEVVTHQI TVQQEQLQLL EEPETVVSRE ESRPPKLVME SVTLPLETLV SPHEESISLC PEEQLVIERL QGEKEQKENS ELSTGLMDSE MTPTIEGCVK DVSYQGGKSI KLSSETESSF SSSADISKAD VSSSPTPSSD LPSHDMLHNY PSALSSSAGN IMPTTYISVT PKIGMGKPAI TKRKFSPGRP RSKQGAWSTH NTVSPPSWSP DISEGREIFK PRQLPGSAIW SIKVGRGSGF PGKRRPRGAG LSGRGGRGRS KLKSGIGAVV LPGVSTADIS SNKDDEENSM HNTVVLFSSS DKFTLNQDMC VVCGSFGQGA EGRLLACSQC GQCYHPYCVS IKITKVVLSK GWRCLECTVC EACGKATDPG RLLLCDDCDI SYHTYCLDPP LQTVPKGGWK CKWCVWCRHC GATSAGLRCE WQNNYTQCAP CASLSSCPVC YRNYREEDLI LQCRQCDRWM HAVCQNLNTE EEVENVADIG FDCSMCRPYM PASNVPSSDC CESSLVAQIV TKVKELDPPK TYTQDGVCLT ESGMTQLQSL TVTVPRRKRS KPKLKLKIIN QNSVAVLQTP PDIQSEHSRD GEMDDSREGE LMDCDGKSES SPEREAVDDE TKGVEGTDGV KKRKRKPYRP GIGGFMVRQR SRTGQGKTKR SVIRKDSSGS ISEQLPCRDD GWSEQLPDTL VDESVSVTES TEKIKKRYRK RKNKLEETFP AYLQEAFFGK DLLDTSRQSK ISLDNLSEDG AQLLYKTNMN TGFLDPSLDP LLSSSSAPTK SGTHGPADDP LADISEVLNT DDDILGIISD DLAKSVDHSD IGPVTDDPSS LPQPNVNQSS RPLSEEQLDG ILSPELDKMV TDGAILGKLY KIPELGGKDV EDLFTAVLSP ANTQPTPLPQ PPPPTQLLPI HNQDAFSRMP LMNGLIGSSP HLPHNSLPPG SGLGTFSAIA QSSYPDARDK NSAFNPMASD PNNSWTSSAP TVEGENDTMS NAQRSTLKWE KEEALGEMAT VAPVLYTNIN FPNLKEEFPD WTTRVKQIAK LWRKASSQER APYVQKARDN RAALRINKVQ MSNDSMKRQQ QQDSIDPSSR IDSELFKDPL KQRESEHEQE WKFRQQMRQK SKQQAKIEAT QKLEQVKNEQ QQQQQQQFGS QHLLVQSGSD TPSSGIQSPL TPQPGNGNMS PAQSFHKELF TKQPPSTPTS TSSDDVFVKP QAPPPPPAPS RIPIQDSLSQ AQTSQPPSPQ VFSPGSSNSR PPSPMDPYAK MVGTPRPPPV GHSFSRRNSA APVENCTPLS SVSRPLQMNE TTANRPSPVR DLCSSSTTNN DPYAKPPDTP RPVMTDQFPK SLGLSRSPVV SEQTAKGPIA AGTSDHFTKP SPRADVFQRQ RIPDSYARPL LTPAPLDSGP GPFKTPMQPP PSSQDPYGSV SQASRRLSVD PYERPALTPR PIDNFSHNQS NDPYSQPPLT PHPAVNESFA HPSRAFSQPG TISRPTSQDP YSQPPGTPRP VVDSYSQSSG TARSNTDPYS QPPGTPRPTT VDPYSQQPQT PRPSTQTDLF VTPVTNQRHS DPYAHPPGTP RPGISVPYSQ PPATPRPRIS EGFTRSSMTR PVLMPNQDPF LQAAQNRGPA LPGPLVRPPD TCSQTPRPPG PGLSDTFSRV SPSAARDPYD QSPMTPRSQS DSFGTSQTAH DVADQPRPGS EGSFCASSNS PMHSQGQQFS GVSQLPGPVP TSGVTDTQNT VNMAQADTEK LRQRQKLREI ILQQQQQKKI AGRQEKGSQD SPAVPHPGPL QHWQPENVNQ AFTRPPPPYP GNIRSPVAPP LGPRYAVFPK DQRGPYPPDV ASMGMRPHGF RFGFPGGSHG TMPSQERFLV PPQQIQGSGV SPQLRRSVSV DMPRPLNNSQ MNNPVGLPQH FSPQSLPVQQ HNILGQAYIE LRHRAPDGRQ RLPFSAPPGS VVEASSNLRH GNFIPRPDFP GPRHTDPMRR PPQGLPNQLP VHPDLEQVPP SQQEQGHSVH SSSMVMRTLN HPLGGEFSEA PLSTSVPSET TSDNLQITTQ PSDGLEEKLD SDDPSVKELD VKDLEGVEVK DLDDEDLENL NLDTEDGKVV ELDTLDNLET NDPNLDDLLR SGEFDIIAYT DPELDMGDKK SMFNEELDLP IDDKLDNQCV SVEPKKKEQE NKTLVLSDKH SPQKKSTVTN EVKTEVLSPN SKVESKCETE KNDENKDNVD TPCSQASAHS DLNDGEKTSL HPCDPDLFEK RTNRETAGPS ANVIQASTQL PAQDVINSCG ITGSTPVLSS LLANEKSDNS DIRPSGSPPP PTLPASPSNH VSSLPPFIAP PGRVLDNAMN SNVTVVSRVN HVFSQGVQVN PGLIPGQSTV NHSLGTGKPA TQTGPQTSQS GTSSMSGPQQ LMIPQTLAQQ NRERPLLLEE QPLLLQDLLD QERQEQQQQR QMQAMIRQRS EPFFPNIDFD AITDPIMKAK MVALKGINKV MAQNNLGMPP MVMSRFPFMG QVVTGTQNSE GQNLGPQAIP QDGSITHQIS RPNPPNFGPG FVNDSQRKQY EEWLQETQQL LQMQQKYLEE QIGAHRKSKK ALSAKQRTAK KAGREFPEED AEQLKHVTEQ QSMVQKQLEQ IRKQQKEHAE LIEDYRIKQQ QQCAMAPPTM MPSVQPQPPL IPGATPPTMS QPTFPMVPQQ LQHQQHTTVI SGHTSPVRMP SLPGWQPNSA PAHLPLNPPR IQPPIAQLPI KTCTPAPGTV SNANPQSGPP PRVEFDDNNP FSESFQERER KERLREQQER QRIQLMQEVD RQRALQQRME MEQHGMVGSE ISSSRTSVSQ IPFYSSDLPC DFMQPLGPLQ QSPQHQQQMG QVLQQQNIQQ GSINSPSTQT FMQTNERRQV GPPSFVPDSP SIPVGSPNFS SVKQGHGNLS GTSFQQSPVR PSFTPALPAA PPVANSSLPC GQDSTITHGH SYPGSTQSLI QLYSDIIPEE KGKKKRTRKK KRDDDAESTK APSTPHSDIT APPTPGISET TSTPAVSTPS ELPQQADQES VEPVGPSTPN MAAGQLCTEL ENKLPNSDFS QATPNQQTYA NSEVDKLSME TPAKTEEIKL EKAETESCPG QEEPKLEEQN GSKVEGNAVA CPVSSAQSPP HSAGAPAAKG DSGNELLKHL LKNKKSSSLL NQKPEGSICS EDDCTKDNKL VEKQNPAEGL QTLGAQMQGG FGCGNQLPKT DGGSETKKQR SKRTQRTGEK AAPRSKKRKK DEEEKQAMYS STDTFTHLKQ QNNLSNPPTP PASLPPTPPP MACQKMANGF ATTEELAGKA GVLVSHEVTK TLGPKPFQLP FRPQDDLLAR ALAQGPKTVD VPASLPTPPH NNQEELRIQD HCGDRDTPDS FVPSSSPESV VGVEVSRYPD LSLVKEEPPE PVPSPIIPIL PSTAGKSSES RRNDIKTEPG TLYFASPFGP SPNGPRSGLI SVAITLHPTA AENISSVVAA FSDLLHVRIP NSYEVSSAPD VPSMGLVSSH RINPGLEYRQ HLLLRGPPPG SANPPRLVSS YRLKQPNVPF PPTSNGLSGY KDSSHGIAES AALRPQWCCH CKVVILGSGV RKSFKDLTLL NKDSRESTKR VEKDIVFCSN NCFILYSSTA QAKNSENKES IPSLPQSPMR ETPSKAFHQY SNNISTLDVH CLPQLPEKAS PPASPPIAFP PAFEAAQVEA KPDELKVTVK LKPRLRAVHG GFEDCRPLNK KWRGMKWKKW SIHIVIPKGT FKPPCEDEID EFLKKLGTSL KPDPVPKDYR KCCFCHEEGD GLTDGPARLL NLDLDLWVHL NCALWSTEVY ETQAGALINV ELALRRGLQM KCVFCHKTGA TSGCHRFRCT NIYHFTCAIK AQCMFFKDKT MLCPMHKPKG IHEQELSYFA VFRRVYVQRD EVRQIASIVQ RGERDHTFRV GSLIFHTIGQ LLPQQMQAFH SPKALFPVGY EASRLYWSTR YANRRCRYLC SIEEKDGRPV FVIRIVEQGH EDLVLSDISP KGVWDKILEP VACVRKKSEM LQLFPAYLKG EDLFGLTVSA VARIAESLPG VEACENYTFR YGRNPLMELP LAVNPTGCAR SEPKMSAHVK RFVLRPHTLN STSTSKSFQS TVTGELNAPY SKQFVHSKSS QYRKMKTEWK SNVYLARSRI QGLGLYAARD IEKHTMVIEY IGTIIRNEVA NRKEKLYESQ NRGVYMFRMD NDHVIDATLT GGPARYINHS CAPNCVAEVV TFERGHKIII SSSRRIQKGE ELCYDYKFDF EDDQHKIPCH CGAVNCRKWM N