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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SMAD4 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001666response to hypoxiaIMP
GO:0001701in utero embryonic developmentIEA
GO:0001702gastrulation with mouth forming secondIEA
GO:0001822kidney developmentIEA
GO:0006351transcription, DNA-dependentIDA
GO:0007179transforming growth factor beta receptor signaling pathwayIDA
GO:0007179transforming growth factor beta receptor signaling pathwayIEA
GO:0007179transforming growth factor beta receptor signaling pathwayTAS
GO:0007183SMAD protein complex assemblyIDA
GO:0007492endoderm developmentIEA
GO:0007498mesoderm developmentIEA
GO:0008285negative regulation of cell proliferationIEA
GO:0009952anterior/posterior pattern specificationIEA
GO:0010718positive regulation of epithelial to mesenchymal transitionIEA
GO:0010718positive regulation of epithelial to mesenchymal transitionISS
GO:0010862positive regulation of pathway-restricted SMAD protein phosphorylationIEA
GO:0010862positive regulation of pathway-restricted SMAD protein phosphorylationISS
GO:0017015regulation of transforming growth factor beta receptor signaling pathwayIMP
GO:0030308negative regulation of cell growthIDA
GO:0030509BMP signaling pathwayIDA
GO:0030509BMP signaling pathwayTAS
GO:0030511positive regulation of transforming growth factor beta receptor signaling pathwayIDA
GO:0032525somite rostral/caudal axis specificationIEA
GO:0032909regulation of transforming growth factor beta2 productionIMP
GO:0042177negative regulation of protein catabolic processIMP
GO:0045892negative regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA
GO:0048589developmental growthIEA
GO:0048663neuron fate commitmentIEA
GO:0048729tissue morphogenesisIEA
GO:0048859formation of anatomical boundaryIEA
GO:0051098regulation of bindingIEA
GO:0060021palate developmentIEA
GO:0060021palate developmentISS
GO:0060391positive regulation of SMAD protein import into nucleusIEA
GO:0060391positive regulation of SMAD protein import into nucleusISS
GO:0060395SMAD protein signal transductionIDA
GO:0060548negative regulation of cell deathIEA
GO:0071559response to transforming growth factor beta stimulusIDA
GO:0072133metanephric mesenchyme morphogenesisIEA
GO:0072134nephrogenic mesenchyme morphogenesisIEA
cellular_component
GO:0005622intracellularIEA
GO:0005634nucleusIDA
GO:0005634nucleusIEA
GO:0005654nucleoplasmTAS
GO:0005667transcription factor complexIDA
GO:0005667transcription factor complexIEA
GO:0005667transcription factor complexIPI
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0005737cytoplasmIEA
GO:0005813centrosomeIDA
GO:0005829cytosolTAS
GO:0032444activin responsive factor complexIDA
GO:0071141SMAD protein complexIDA
molecular_function
GO:0000987core promoter proximal region sequence-specific DNA bindingIDA
GO:0000988protein binding transcription factor activityIDA
GO:0003677DNA bindingIDA
GO:0003677DNA bindingIEA
GO:0003682chromatin bindingIEA
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0005515protein bindingIPI
GO:0005518collagen bindingIEA
GO:0030616transforming growth factor beta receptor, common-partner cytoplasmic mediator activityIDA
GO:0042802identical protein bindingIPI
GO:0042803protein homodimerization activityIPI
GO:0043565sequence-specific DNA bindingIDA
GO:0044212transcription regulatory region DNA bindingIDA
GO:0046332SMAD bindingIEA
GO:0070411I-SMAD bindingIPI
GO:0070412R-SMAD bindingIPI

Protein-protein interaction details for SMAD4 (Homo sapiens)
(Information is obtained from BioGRID)
Not available