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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for Il6 (Rattus norvegicus) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001781 neutrophil apoptosis IEA GO:0001781 neutrophil apoptosis ISO GO:0001878 response to yeast IEP GO:0002384 hepatic immune response IEA GO:0002384 hepatic immune response ISO GO:0002675 positive regulation of acute inflammatory response IEA GO:0002675 positive regulation of acute inflammatory response ISO GO:0006469 negative regulation of protein kinase activity IDA GO:0006953 acute-phase response IEA GO:0006954 inflammatory response IEA GO:0006954 inflammatory response ISO GO:0006955 immune response IEA GO:0007568 aging IEP GO:0008284 positive regulation of cell proliferation ISO GO:0008285 negative regulation of cell proliferation IMP GO:0008360 regulation of cell shape IDA GO:0009408 response to heat IEP GO:0009409 response to cold IEP GO:0009611 response to wounding IEP GO:0009611 response to wounding ISO GO:0009612 response to mechanical stimulus IEP GO:0009617 response to bacterium IEP GO:0010574 regulation of vascular endothelial growth factor production IEA GO:0010574 regulation of vascular endothelial growth factor production ISO GO:0010628 positive regulation of gene expression IDA GO:0014070 response to organic cyclic compound IEP GO:0016049 cell growth IDA GO:0019221 cytokine-mediated signaling pathway ISO GO:0031000 response to caffeine IEP GO:0031018 endocrine pancreas development IEA GO:0031018 endocrine pancreas development ISO GO:0031175 neuron projection development IEA GO:0031175 neuron projection development ISO GO:0031667 response to nutrient levels IEP GO:0032494 response to peptidoglycan IEA GO:0032494 response to peptidoglycan ISO GO:0032496 response to lipopolysaccharide IEP GO:0032722 positive regulation of chemokine production IEA GO:0032722 positive regulation of chemokine production ISO GO:0032755 positive regulation of interleukin-6 production IEA GO:0032755 positive regulation of interleukin-6 production ISO GO:0032868 response to insulin stimulus IEP GO:0032966 negative regulation of collagen biosynthetic process IEA GO:0032966 negative regulation of collagen biosynthetic process ISO GO:0033138 positive regulation of peptidyl-serine phosphorylation IEA GO:0033138 positive regulation of peptidyl-serine phosphorylation ISO GO:0033160 positive regulation of protein import into nucleus, translocation IDA GO:0034097 response to cytokine stimulus IEP GO:0042102 positive regulation of T cell proliferation IEA GO:0042102 positive regulation of T cell proliferation ISO GO:0042127 regulation of cell proliferation ISO GO:0042493 response to drug IEP GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein IDA GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein ISO GO:0042832 defense response to protozoan IEA GO:0042832 defense response to protozoan ISO GO:0042981 regulation of apoptosis ISO GO:0043066 negative regulation of apoptosis IEA GO:0043066 negative regulation of apoptosis ISO GO:0043154 negative regulation of caspase activity IDA GO:0043200 response to amino acid stimulus IEP GO:0043410 positive regulation of MAPKKK cascade ISO GO:0043526 neuroprotection IDA GO:0045079 negative regulation of chemokine biosynthetic process IEA GO:0045079 negative regulation of chemokine biosynthetic process ISO GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep IMP GO:0045429 positive regulation of nitric oxide biosynthetic process IDA GO:0045454 cell redox homeostasis IMP GO:0045630 positive regulation of T-helper 2 cell differentiation IEA GO:0045630 positive regulation of T-helper 2 cell differentiation ISO GO:0045666 positive regulation of neuron differentiation IMP GO:0045721 negative regulation of gluconeogenesis IDA GO:0045727 positive regulation of translation IEA GO:0045727 positive regulation of translation ISO GO:0045740 positive regulation of DNA replication IMP GO:0045768 positive regulation of anti-apoptosis IEA GO:0045768 positive regulation of anti-apoptosis ISO GO:0045893 positive regulation of transcription, DNA-dependent ISO GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter ISO GO:0046427 positive regulation of JAK-STAT cascade IDA GO:0046427 positive regulation of JAK-STAT cascade ISO GO:0046677 response to antibiotic IEP GO:0046716 muscle cell homeostasis IEA GO:0046716 muscle cell homeostasis ISO GO:0046849 bone remodeling IEP GO:0046888 negative regulation of hormone secretion IEA GO:0046888 negative regulation of hormone secretion ISO GO:0048635 negative regulation of muscle organ development IDA GO:0048661 positive regulation of smooth muscle cell proliferation IEA GO:0048661 positive regulation of smooth muscle cell proliferation ISO GO:0050679 positive regulation of epithelial cell proliferation IEA GO:0050679 positive regulation of epithelial cell proliferation ISO GO:0050710 negative regulation of cytokine secretion IDA GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation ISO GO:0050829 defense response to Gram-negative bacterium IEA GO:0050829 defense response to Gram-negative bacterium ISO GO:0050830 defense response to Gram-positive bacterium IEA GO:0050830 defense response to Gram-positive bacterium ISO GO:0050871 positive regulation of B cell activation IEA GO:0050871 positive regulation of B cell activation ISO GO:0051024 positive regulation of immunoglobulin secretion IEA GO:0051024 positive regulation of immunoglobulin secretion ISO GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity IEA GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity ISO GO:0051092 positive regulation of NF-kappaB transcription factor activity ISO GO:0051384 response to glucocorticoid stimulus IEA GO:0051384 response to glucocorticoid stimulus ISO GO:0051592 response to calcium ion IEP GO:0051602 response to electrical stimulus IEP GO:0051607 defense response to virus IEA GO:0051607 defense response to virus ISO GO:0051897 positive regulation of protein kinase B signaling cascade IDA GO:0051971 positive regulation of transmission of nerve impulse IDA GO:0060445 branching involved in salivary gland morphogenesis IEA GO:0060445 branching involved in salivary gland morphogenesis ISO GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis IEA GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis ISO GO:0070091 glucagon secretion IEA GO:0070091 glucagon secretion ISO GO:0070102 interleukin-6-mediated signaling pathway IEA GO:0070102 interleukin-6-mediated signaling pathway ISO GO:0070301 cellular response to hydrogen peroxide IEA GO:0070301 cellular response to hydrogen peroxide ISO GO:0070374 positive regulation of ERK1 and ERK2 cascade IDA cellular_component GO:0005576 extracellular region IEA GO:0005615 extracellular space IDA GO:0005615 extracellular space ISO GO:0005896 interleukin-6 receptor complex IEA GO:0005896 interleukin-6 receptor complex ISO GO:0009897 external side of plasma membrane IEA GO:0009897 external side of plasma membrane ISO molecular_function GO:0005102 receptor binding IDA GO:0005125 cytokine activity IDA GO:0005125 cytokine activity ISO GO:0005138 interleukin-6 receptor binding IDA GO:0005138 interleukin-6 receptor binding ISO GO:0008083 growth factor activity IEA GO:0008083 growth factor activity ISO

Protein-protein interaction details for Il6 (Rattus norvegicus) (Information is obtained from BioGRID)

Not available