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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for DRD4 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000187activation of MAPK activityIDA
GO:0001662behavioral fear responseNAS
GO:0001963synaptic transmission, dopaminergicIEA
GO:0001975response to amphetamineISS
GO:0006874cellular calcium ion homeostasisIC
GO:0007194negative regulation of adenylate cyclase activityIDA
GO:0007195inhibition of adenylate cyclase activity by dopamine receptor signaling pathwayIDA
GO:0007212dopamine receptor signaling pathwayIDA
GO:0007614short-term memoryIEA
GO:0008344adult locomotory behaviorISS
GO:0008355olfactory learningIEA
GO:0030818negative regulation of cAMP biosynthetic processIDA
GO:0032417positive regulation of sodium:hydrogen antiporter activityIDA
GO:0033674positive regulation of kinase activityIDA
GO:0034776response to histamineIDA
GO:0035176social behaviorNAS
GO:0042053regulation of dopamine metabolic processISS
GO:0042417dopamine metabolic processIC
GO:0042596fear responseISS
GO:0046928regulation of neurotransmitter secretionIEA
GO:0048148behavioral response to cocaineISS
GO:0048149behavioral response to ethanolTAS
GO:0050482arachidonic acid secretionIDA
GO:0050709negative regulation of protein secretionIDA
GO:0050848regulation of calcium-mediated signalingIEA
GO:0051586positive regulation of dopamine uptakeIC
GO:0051927negative regulation of calcium ion transport via voltage-gated calcium channel activityIDA
GO:0060080regulation of inhibitory postsynaptic membrane potentialISS
cellular_component
GO:0005737cytoplasmIEA
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneIDA
GO:0005938cell cortexIEA
GO:0012506vesicle membraneIEA
GO:0016020membraneIDA
GO:0030424axonIEA
GO:0043025neuronal cell bodyIEA
GO:0043195terminal buttonIEA
GO:0043197dendritic spineIEA
molecular_function
GO:0001591dopamine receptor activity, coupled via Gi/GoIDA
GO:0001593dopamine D4 receptor activityISS
GO:0004871signal transducer activityIEA
GO:0004872receptor activityIEA
GO:0004930G-protein coupled receptor activityIEA
GO:0004952dopamine receptor activityIDA
GO:0005515protein bindingIPI
GO:0008144drug bindingIDA
GO:0015459potassium channel regulator activityNAS
GO:0017124SH3 domain bindingIDA
GO:0035240dopamine bindingIDA

Protein-protein interaction details for DRD4 (Homo sapiens)
(Information is obtained from BioGRID)
Not available