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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for DRD4 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000187
activation of MAPK activity
IDA
GO:0001662
behavioral fear response
NAS
GO:0001963
synaptic transmission, dopaminergic
IEA
GO:0001975
response to amphetamine
ISS
GO:0006874
cellular calcium ion homeostasis
IC
GO:0007194
negative regulation of adenylate cyclase activity
IDA
GO:0007195
inhibition of adenylate cyclase activity by dopamine receptor signaling pathway
IDA
GO:0007212
dopamine receptor signaling pathway
IDA
GO:0007614
short-term memory
IEA
GO:0008344
adult locomotory behavior
ISS
GO:0008355
olfactory learning
IEA
GO:0030818
negative regulation of cAMP biosynthetic process
IDA
GO:0032417
positive regulation of sodium:hydrogen antiporter activity
IDA
GO:0033674
positive regulation of kinase activity
IDA
GO:0034776
response to histamine
IDA
GO:0035176
social behavior
NAS
GO:0042053
regulation of dopamine metabolic process
ISS
GO:0042417
dopamine metabolic process
IC
GO:0042596
fear response
ISS
GO:0046928
regulation of neurotransmitter secretion
IEA
GO:0048148
behavioral response to cocaine
ISS
GO:0048149
behavioral response to ethanol
TAS
GO:0050482
arachidonic acid secretion
IDA
GO:0050709
negative regulation of protein secretion
IDA
GO:0050848
regulation of calcium-mediated signaling
IEA
GO:0051586
positive regulation of dopamine uptake
IC
GO:0051927
negative regulation of calcium ion transport via voltage-gated calcium channel activity
IDA
GO:0060080
regulation of inhibitory postsynaptic membrane potential
ISS
cellular_component
GO:0005737
cytoplasm
IEA
GO:0005886
plasma membrane
TAS
GO:0005887
integral to plasma membrane
IDA
GO:0005938
cell cortex
IEA
GO:0012506
vesicle membrane
IEA
GO:0016020
membrane
IDA
GO:0030424
axon
IEA
GO:0043025
neuronal cell body
IEA
GO:0043195
terminal button
IEA
GO:0043197
dendritic spine
IEA
molecular_function
GO:0001591
dopamine receptor activity, coupled via Gi/Go
IDA
GO:0001593
dopamine D4 receptor activity
ISS
GO:0004871
signal transducer activity
IEA
GO:0004872
receptor activity
IEA
GO:0004930
G-protein coupled receptor activity
IEA
GO:0004952
dopamine receptor activity
IDA
GO:0005515
protein binding
IPI
GO:0008144
drug binding
IDA
GO:0015459
potassium channel regulator activity
NAS
GO:0017124
SH3 domain binding
IDA
GO:0035240
dopamine binding
IDA
Protein-protein interaction details for DRD4 (
Homo sapiens
)
(Information is obtained from BioGRID)
Not available