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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for DRD2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001659 temperature homeostasis IEA GO:0001659 temperature homeostasis ISS GO:0001666 response to hypoxia IEA GO:0001963 synaptic transmission, dopaminergic IEA GO:0001975 response to amphetamine IEA GO:0001975 response to amphetamine ISS GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure IEA GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure ISS GO:0002027 regulation of heart rate IEA GO:0002027 regulation of heart rate ISS GO:0002028 regulation of sodium ion transport IEA GO:0002028 regulation of sodium ion transport ISS GO:0002031 G-protein coupled receptor internalization IEA GO:0002052 positive regulation of neuroblast proliferation IEA GO:0002052 positive regulation of neuroblast proliferation ISS GO:0002092 positive regulation of receptor internalization IEA GO:0006874 cellular calcium ion homeostasis IC GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger IEA GO:0007194 negative regulation of adenylate cyclase activity IDA GO:0007194 negative regulation of adenylate cyclase activity IEA GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway IDA GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway IEA GO:0007243 intracellular protein kinase cascade IDA GO:0007270 neuron-neuron synaptic transmission ISS GO:0007409 axonogenesis IEA GO:0007409 axonogenesis ISS GO:0007416 synapse assembly IEA GO:0007416 synapse assembly ISS GO:0007608 sensory perception of smell IEA GO:0007608 sensory perception of smell ISS GO:0007616 long-term memory IEA GO:0007625 grooming behavior IEA GO:0007626 locomotory behavior IEA GO:0007626 locomotory behavior ISS GO:0007628 adult walking behavior IEA GO:0007628 adult walking behavior ISS GO:0007631 feeding behavior IEA GO:0008104 protein localization IEA GO:0008104 protein localization ISS GO:0008285 negative regulation of cell proliferation IEA GO:0008285 negative regulation of cell proliferation ISS GO:0008306 associative learning ISS GO:0008542 visual learning IEA GO:0008542 visual learning ISS GO:0009416 response to light stimulus IEA GO:0009416 response to light stimulus ISS GO:0009636 response to toxin IEA GO:0010039 response to iron ion IEA GO:0014059 regulation of dopamine secretion IEA GO:0016055 Wnt receptor signaling pathway IEA GO:0021853 cerebral cortex GABAergic interneuron migration IEA GO:0021853 cerebral cortex GABAergic interneuron migration ISS GO:0021984 adenohypophysis development IEA GO:0021984 adenohypophysis development ISS GO:0030336 negative regulation of cell migration IEA GO:0030336 negative regulation of cell migration ISS GO:0030432 peristalsis IEA GO:0030432 peristalsis ISS GO:0030814 regulation of cAMP metabolic process IDA GO:0030900 forebrain development IEA GO:0031223 auditory behavior IEA GO:0032147 activation of protein kinase activity IEA GO:0032228 regulation of synaptic transmission, GABAergic IEA GO:0032228 regulation of synaptic transmission, GABAergic ISS GO:0032922 circadian regulation of gene expression IEA GO:0032922 circadian regulation of gene expression ISS GO:0034776 response to histamine IDA GO:0035094 response to nicotine IEA GO:0035810 positive regulation of urine volume IEA GO:0035815 positive regulation of renal sodium excretion IEA GO:0040018 positive regulation of multicellular organism growth IEA GO:0042220 response to cocaine ISS GO:0042321 negative regulation of circadian sleep/wake cycle, sleep IEA GO:0042417 dopamine metabolic process IC GO:0042417 dopamine metabolic process IEA GO:0042493 response to drug IEA GO:0042493 response to drug ISS GO:0043266 regulation of potassium ion transport IEA GO:0043266 regulation of potassium ion transport ISS GO:0043278 response to morphine IEA GO:0043278 response to morphine ISS GO:0043408 regulation of MAPKKK cascade IEA GO:0043473 pigmentation IEA GO:0043666 regulation of phosphoprotein phosphatase activity IEA GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway IEA GO:0045776 negative regulation of blood pressure IEA GO:0045776 negative regulation of blood pressure ISS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0046488 phosphatidylinositol metabolic process IEA GO:0046488 phosphatidylinositol metabolic process ISS GO:0046676 negative regulation of insulin secretion IEA GO:0046717 acid secretion IEA GO:0048148 behavioral response to cocaine IEA GO:0048148 behavioral response to cocaine ISS GO:0048149 behavioral response to ethanol IEA GO:0048149 behavioral response to ethanol ISS GO:0048169 regulation of long-term neuronal synaptic plasticity IEA GO:0048169 regulation of long-term neuronal synaptic plasticity ISS GO:0048678 response to axon injury IEA GO:0048755 branching morphogenesis of a nerve IEA GO:0048755 branching morphogenesis of a nerve ISS GO:0050482 arachidonic acid secretion IDA GO:0050709 negative regulation of protein secretion IDA GO:0051209 release of sequestered calcium ion into cytosol IEA GO:0051209 release of sequestered calcium ion into cytosol ISS GO:0051481 reduction of cytosolic calcium ion concentration IEA GO:0051482 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger IDA GO:0051584 regulation of dopamine uptake IC GO:0051586 positive regulation of dopamine uptake IEA GO:0051586 positive regulation of dopamine uptake ISS GO:0051898 negative regulation of protein kinase B signaling cascade ISS GO:0051927 negative regulation of calcium ion transport via voltage-gated calcium channel activity IDA GO:0051927 negative regulation of calcium ion transport via voltage-gated calcium channel activity IEA GO:0051967 negative regulation of synaptic transmission, glutamatergic IEA GO:0051967 negative regulation of synaptic transmission, glutamatergic ISS GO:0060124 positive regulation of growth hormone secretion IEA GO:0060124 positive regulation of growth hormone secretion ISS GO:0060134 prepulse inhibition IEA GO:0060134 prepulse inhibition ISS GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway IEA GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway IGI GO:0060160 negative regulation of dopamine receptor signaling pathway IEA GO:0060160 negative regulation of dopamine receptor signaling pathway ISS GO:0070374 positive regulation of ERK1 and ERK2 cascade IEA cellular_component GO:0001669 acrosomal vesicle IEA GO:0005625 soluble fraction IEA GO:0005886 plasma membrane IEA GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane IC GO:0005887 integral to plasma membrane IDA GO:0014069 postsynaptic density IEA GO:0016021 integral to membrane IEA GO:0016328 lateral plasma membrane IEA GO:0019861 flagellum IEA GO:0030139 endocytic vesicle IEA GO:0030424 axon IEA GO:0030424 axon ISS GO:0030425 dendrite ISS GO:0030672 synaptic vesicle membrane IEA GO:0031410 cytoplasmic vesicle IEA GO:0043197 dendritic spine IEA GO:0043204 perikaryon IEA GO:0043679 axon terminus IEA molecular_function GO:0001591 dopamine receptor activity, coupled via Gi/Go IDA GO:0001670 dopamine D2 receptor activity IDA GO:0001670 dopamine D2 receptor activity IEA GO:0004871 signal transducer activity IEA GO:0004872 receptor activity IEA GO:0004930 G-protein coupled receptor activity IEA GO:0004952 dopamine receptor activity IEA GO:0005102 receptor binding IEA GO:0005515 protein binding IPI GO:0008144 drug binding IDA GO:0008144 drug binding IEA GO:0015459 potassium channel regulator activity NAS GO:0035255 ionotropic glutamate receptor binding IEA

Protein-protein interaction details for DRD2 (Homo sapiens) (Information is obtained from BioGRID)

Not available