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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for OSBPL2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9885
Official gene symbolOSBPL2
Full nameoxysterol binding protein-like 2
Aliases,FLJ20223,KIAA0772,MGC4307,MGC8342,ORP-2,ORP2,
Gene summaryThis gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q13.3
Gene position60813580 - 60871269  Map Viewer
Gene orientationplus
Gene size57690 bp
Gene sequence
OMIM ID606731