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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KLK4 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 9622 Official gene symbol KLK4 Full name kallikrein-related peptidase 4 Aliases ,AI2A1,ARM1,EMSP,EMSP1,KLK-L1,MGC116827,MGC116828,PRSS17,PSTS, Gene summary Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Alternate splice variants for this gene have been described, but their biological validity has not been determined. [provided by RefSeq] Location Chromosome: 19   Locus: 19q13.41 Gene position 51413994 - 51409608  Map Viewer Gene orientation minus Gene size 4387 bp Gene sequence >KLK4:complement(23677826..23682212):Length=4387 ATGGCCACAGCAGGAAATCCCTGGGGCTGGTTCCTGGGGTACCTCATCCTTGGTGTCGCA GGTATCTGAGTATGCGTGTGTGTGTCTGTCCGTGCTTGGGGGCACAGTGTTTGTTAATGT TCAGGTGTGACTCAGTGTCCTCTTGCTTGTGACTGCAAAGCTGCCTGTGAGACGGTACCG TGTTATCCGTCCCCCATGGCTGTGCCCCTGCAACTCCTTGTATCGTGGTAAATTTGTGTG TGGCAGTGTGCCTGGGTGTGTGGTTGTACCTGTGAGACTCTGACAGTTTGTGCCTCTGAA TATCTGGTGGAGTGACAACAGTGTAATGATGATATGGGGACAGGGGAAGCCGAGGGTGCA GGAGATTGTGCTTCCTGGGGCGTGATCCATTGCTGGGAATCTGTGCCTGCTTCCTGGGTC TTCAGTCCTGAGATCCCCCTCTCCCATCCCCAAGGAACTCACCTCACAGGACTATAAAAC GGTGTTTTGGTGTGCATGGGCTTGTGGCTTGGTGTGACTGTGGGCAAGGCTGGGAGAGGA TAGGAGTGACTCGGCGCAGGACCGACTCTTTGAGCATCAGTCTGCGCAGACAAGTGACCC GATCCTTGCTCCCAGCAACAACTCCACCCCCTGAGCTTTAATTCACCCCGAAGGACCCGA TCCTACTGCTATGAGCCTAGACTCCTCTGTTGAACCCCTCCTGACCGTGGCTTTGCACCG CGATGGCACCAGTCTCACCTCCAGAGCTCACCCCAGAGCCCTGACTCCGCCCCAGAAGCC CTGGTCCCACCTTCTGAGACTGCCTCTAGCCATAACCCAGCTCTTGAAGCCTTGATGGCG CCCCTGCGCTGTAACCCCAACCCTAGGAGCACTGATCCCGCCTTCTCAGCCCACCCCCAT GCCCTGACTCTCCTCCCAGGAGCCCTGACTACCCTGAATCCCTGACCAGGCTCCTGCACC GTGATCACCGCCCCTGGGAGCCCTAGGCCTATATCCTGGACCAGCCCCTGAAGCTCCGAT CATGACCCCTGCACCATAACCCCACCCCCAGGAGCCCTGGGTCCGCCCCCTGGGCCCGCC CCCAGCCCTGACTCGGCCCCCCAAGAGTCCTGACTGCTCCTGAAGCCCTGACCACGCCCC TGCTCGGTAACCCCTCCCCCAAGAGCCCTGGGCCCGCCTCCTGAGCCCGTTCCCAGCCCT GACTCCGCCCCGAGGAGCCCTGACTGCTCCTGAACCTCTGACCACGCCCCTGCTCGGTAA GCCCACCCCCAGGAACCCTGGGCCCGCCTCCTGGTCCCGATCCCATCCCTGACTCCGCCC TCAGGATCGCTCGTCTCTGGTAGCTGCAGCCAAATCATAAACGGCGAGGACTGCAGCCCG CACTCGCAGCCCTGGCAGGCGGCACTGGTCATGGAAAACGAATTGTTCTGCTCGGGCGTC CTGGTGCATCCGCAGTGGGTGCTGTCAGCCGCACACTGTTTCCAGAAGTGAGTGCAGAGG TAGGGGGAGTGGGCAGGGCCTGGGTCCGGGGGCGGGGCCTAATATCAGGCTCATCTTGGG GTGCTCAGGGGGAAACAGCGGTGAAGGCTCTGGGAGGAGGACGGAATGAGCCTGGATCCG GGGAGCCCCAGAGGGAAGGGCTGGGAGGCGGGAATCTTGCTTCGGAAGGACTCAGAGAGT CCTGACTTGAAATCTCAGCCCAGTGCTGAGTCTCTAGTGAACTAAGGCAAGTTCTTGTCC CTGAATTTTTGTGAATGAGGATTTGAGACCATGGTTAAGTAGCTCTTAGGGTGTTTAGCG AAGAGGGTGGGGTTGGGGTTAGGAGATGGGGATGGGAATGGGGTTGAAGATGAGAATGGA GGTAAGGATGTAGTTGCCACAAAACTGACCTGCCCTCCGTGGCCCACAGCTCCTACACCA TCGGGCTGGGCCTGCACAGTCTTGAGGCCGACCAAGAGCCAGGGAGCCAGATGGTGGAGG CCAGCCTCTCCGTACGGCACCCAGAGTACAACAGACCCTTGCTCGCTAACGACCTCATGC TCATCAAGTTGGACGAATCCGTGTCCGAGTCTGACACCATCCGGAGCATCAGCATTGCTT CGCAGTGCCCTACCGCGGGGAACTCTTGCCTCGTTTCTGGCTGGGGTCTGCTGGCGAACG GTGAGCTCACGGGTGTGTGTCTGCCCTCTTCAAGGAGGTCCTCTGCCCAGTCGCGGGGGC TGACCCAGAGCTCTGCGTCCCAGGCAGAATGCCTACCGTGCTGCAGTGCGTGAACGTGTC GGTGGTGTCTGAGGAGGTCTGCAGTAAGCTCTATGACCCGCTGTACCACCCCAGCATGTT CTGCGCCGGCGGAGGGCACGACCAGAAGGACTCCTGCAACGTGAGAGAGGGGAAAGGGGA GGGCAGGCGACTCAGGGAAGGGTGGAGAAGGGGGAGACAGAGACACACAGGGCCGCATGG CGAGATGCAGAGATGGAGAGACACACAGGGAGACAGTGACAACTAGAGAGAGAAACTGAG AGAAACAGAGAAATAAACACAGGAATAAAGAGAAGCAAAGGAAGAGAGAAACAGAAACAG ACATGGGGAGGCAGAAACACACACACATAGAAATGCAGTTGACCTTCCAACAGCATGGGG CCTGAGGGCGGTGACCTCCACCCAACAGAAAATCCTCTTATAACTTTTGACTCCCCAAAA ACCTGACTAGAAATAGCCTACTGTTGACGGGGAGCCTTACCAATAACATAAATAGTCGAT TTATGCATACGTTTTATGCATTCATGATATACCTTTGTTGGAATTTTTTGATATTTCTAA GCTACACAGTTCGTCTGTGAATTTTTTTAAATTGTTGCAACTCTCCTAAAATTTTTCTAA TGTGTTTATTGAAAAAATCCAAGTATAAGTGGACTTGTGCAGTTCAAACCAGGGTTGTTC AAGGGTCAACTGTGTACCCAGAGGGAAACAGTGACACAGATTCATAGAGGTGAAACACGA AGAGAAACAGGAAAAATCAAGACTCTACAAAGAGGCTGGGCAGGGTGGCTCATGCCTGTA ATCCCAGCACTTTGGGAGGCGAGGCAGGCAGATCACTTGAGGTAAGGAGTTCAAGACCAG CCTGGCCAAAATGGTGAAATCCTGTCTGTACTAAAAATACAAAAGTTAGCTGGATATGGT GGCAGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGAAGAATTGCTTGAATATG GGAGGCAGAGGTTGAAGTGAGTTGAGATCACACCACTATACTCCAGCTGGGGCAACAGAG TAAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAGACTTTACAAAGAGATGCAGAGACAC TGAGACAGATAAACAAGCCACAAAGGAGACAAAGGAGAGACAGACAAACAGAAACAGACA GACCACAAGCCCAAGAGAAGCAGCCAGCATTCAGGACATAGGACATCGGGAAGCAGGATT AGATGAAGTCAGGGATCTGGAATGGGACTTCCAACAGATATGTTGCTGGGCTATGTTGTT ATTGATGATGGTTCTGTCTTTGTTTCTCAGTCTCATTTAGTTCCTTTCTGAGCCCACATC CATTTCCACCTCTCTGTGTTTTGAATTCTGACTCTCCCTCTCTTCACAACAGGGTGACTC TGGGGGGCCCCTGATCTGCAACGGGTACTTGCAGGGCCTTGTGTCTTTCGGAAAAGCCCC GTGTGGCCAAGTTGGCGTGCCAGGTGTCTACACCAACCTCTGCAAATTCACTGAGTGGAT AGAGAAAACCGTCCAGGCCAGTTAACTCTGGGGACTGGGAACCCATGAAATTGACCCCCA AATACATCCTGCGGAAGGAATTCAGGAATATCTGTTCCCAGCCCCTCCTCCCTCAGGCCC AGGAGTCCAGGCCCCCAGCCCCTCCTCCCTCAAACCAAGGGTACAGATCCCCAGCCCCTC CTCCCTCAGACCCAGGAGTCCAGACCCCCCAGCCCCTCCTCCCTCAGACCCAGGAGTCCA GCCCCTCCTCCCTCAGACCCAGGAGTCCAGACCCCCCAGCCCCTCCTCCCTCAGACCCAG GAGTCCAGCCCCTCCTCCCTCAGACCCAGGAGTCCAGACCCCCCAGCCCCTCCTCCCTCA GACCCAGGGGTCCAGGCCCCCAACCCCTCCTCCCTCAGACTCAGAGGTCCAGGCCCCCAA CCCCTCCTTCCCCAGACCCAGAGGTCCAGGTCCCAGCCCCTCCTCCCTCAGACCCAGCGG TCCAATGCCACCTAGACTCTCCCTGTACACAGTGCCCCCTTGTGGCACGTTGACCCAACC TTACCAGTTGGTTTTTCATTTTTTGTCCCTTTCCCCTAGATCCAGAAATAAAGTCTAAGA GAAGCGC OMIM ID 603767