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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for EEF1E1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID9521
Official gene symbolEEF1E1
Full nameeukaryotic translation elongation factor 1 epsilon 1
Aliases,AIMP3,P18,
Gene summaryThis gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq]
LocationChromosome: 6   Locus: 6p24.3-p25.1
Gene position8102828 - 8073593  Map Viewer
Gene orientationminus
Gene size29236 bp
Gene sequence
OMIM ID609206