| Entrez gene ID | | 9521 |
| Official gene symbol | | EEF1E1 |
| Full name | | eukaryotic translation elongation factor 1 epsilon 1 |
| Aliases | | ,AIMP3,P18, |
| Gene summary | | This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq] |
| Location | | Chromosome: 6 Locus: 6p24.3-p25.1 |
| Gene position | | 8102828 - 8073593 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 29236 bp |
| Gene sequence |
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| OMIM ID | | 609206 |
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