| Entrez gene ID | | 8813 |
| Official gene symbol | | DPM1 |
| Full name | | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit |
| Aliases | | ,CDGIE,MPDS, |
| Gene summary | | Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. [provided by RefSeq] |
| Location | | Chromosome: 20 Locus: 20q13.13 |
| Gene position | | 49575060 - 49551405 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 23656 bp |
| Gene sequence |
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| OMIM ID | | 603503 |