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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DYNLL1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8655
Official gene symbolDYNLL1
Full namedynein, light chain, LC8-type 1
Aliases,DLC1,DLC8,DNCL1,DNCLC1,LC8,LC8a,MGC126137,MGC126138,PIN,hdlc1,
Gene summaryCytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q24.23
Gene position120907660 - 120936298  Map Viewer
Gene orientationplus
Gene size28639 bp
Gene sequence
OMIM ID601562