| Entrez gene ID | | 83999 |
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| Official gene symbol | | KREMEN1 |
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| Full name | | kringle containing transmembrane protein 1 |
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| Aliases | | ,FLJ31863,KREMEN,KRM1, |
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| Gene summary | | This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq] |
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| Location | | Chromosome: 22 Locus: 22q12.1 |
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| Gene position | | 29469066 - 29564321 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 95256 bp |
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| Gene sequence |
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| OMIM ID | | 609898 |
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