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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FZD8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8325
Official gene symbolFZD8
Full namefrizzled homolog 8 (Drosophila)
Aliases,FZ-8,hFZ8,
Gene summaryThis intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq]
LocationChromosome: 10   Locus: 10p11.21
Gene position35930362 - 35927177  Map Viewer
Gene orientationminus
Gene size3186 bp
Gene sequence
OMIM ID606146