| Entrez gene ID | | 8324 |
|
| Official gene symbol | | FZD7 |
|
| Full name | | frizzled homolog 7 (Drosophila) |
|
| Aliases | | ,FzE3, |
|
| Gene summary | | Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq] |
|
| Location | | Chromosome: 2 Locus: 2q33 |
|
| Gene position | | 202899310 - 202903160 Map Viewer |
|
| Gene orientation | | plus |
|
| Gene size | | 3851 bp |
|
| Gene sequence |
| |
|
| OMIM ID | | 603410 |
|
|
|
