| Entrez gene ID | | 689588 |
|
| Official gene symbol | | Oaz3 |
|
| Full name | | ornithine decarboxylase antizyme 3 |
|
| Aliases | | Az3,Oaz-t |
|
| Gene summary | | Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of antizyme 3, encoded by this gene, is restricted to testis germ cells. [provided by RefSeq] |
|
| Location | | Chromosome: 2 Locus: 2q34 |
|
| Gene position | | 189411500 - 189408566 Map Viewer |
|
| Gene orientation | | minus |
|
| Gene size | | 2935 bp |
|
| Gene sequence |
| |
|
