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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for Dio2 (Rattus norvegicus) (Information is obtained from NCBI Gene database)

Entrez gene ID 65162 Official gene symbol Dio2 Full name deiodinase, iodothyronine, type II Aliases 5DII,DIOII Gene summary The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). The expression of this gene in some tissues is regulated by the level of thyroid hormone. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq] Location Chromosome: 6   Locus: 6q31 Gene position 114307757 - 114317562  Map Viewer Gene orientation minus Gene size 9806 bp Gene sequence >Dio2:complement(9648146..9657951):Length=9806 CCCAAACAACCCTTGCGCTTACAGCACAGTTAAGAAATTGGCAGTGTAAGAAGCCAGACT GCGTTTAAAGGAACATGAAAAGCTAAAAGAAATTTTTACCATCTCTGCAGTCTCATAGGT GCCTGGAAATGAAAGTAGAACTTCCTGTCTTTAACGGACTCTGACAGGGGTAAACTGGAT TAGGGACTGGCACGCCAGGGTGTTGTTGTTGTTGTTGTTGTTGTTTTGTTGTTGTTGTTG CTGGGAGTGGTGGTGTTTTGTTTTTTTTTTTTAACCATCTTAAATCCTGGAAAAAAAATG CATCTCGGAATTGAATGAATTGATGGGTCCACTCCAACTGCTGGGCTGCAGAGACTGAAC TTGGTCTTTCCATTTCTGCTTCTTTCAAAGAAGAGACAAGTTGGGATCCCTTCTAATTTA GCTTTTCTCCCTCTCCCTCACCCCCCACCCCCACTCCCAACCTTCCCCTTGGTCCCCCAC TTCTCTACCACCACCTTCCTTTGCAAAAAGGGGGTGACCGGGGAAGCAGAGTGCACAGGA GACTGACTGAGGAGGTAAAGAAGATGGGACTCCTCAGCGTAGACTTGCTGATCACTCTTC AGATTCTGCCAGTCTTTTTCTCCAACTGCCTCTTCCTGGCGCTCTATGACTCGGTCATTC TGCTCAAGCACGTGGCGCTGCTTCTCAGCCGCTCCAAGTCCACTCGCGGAGAGTGGAGGC GCATGCTGACCTCAGAAGGACTACGCTGTGTCTGGAACAGCTTTCTCCTAGACGCCTACA AACAGGTGAGCTTCATCTGCTGAGCTTCTCCTGGGTCGCAGAACCAGGGGGCTGGAAGAT GTGAGGCTGCTGGCCATGGGGAATCCGATCTGGGGTGGCCTCTCAAGTGATTACTTACGT TCAAGGGAGTCCCAGTGCCACTCGGGGCACCTGTTACACAGGTTAGATTTGGGAGTGACA GATATTGAGCCCCAGGGACTCTGAGTGACTTCAGCAGGAGTCTTTAATGAAGGCTGTTGT TACTTTGCACTGAATTGGCAGTTTAAGGGTTTTGTGCTGGGATAAGATAACTCTAAGTAA AAATCAGAATTTGGGCCGGGGTGGGGTGGGGAGTGGGGAGTGGCTTGGAACTTGCTGCAT TTGTTCTGCCCTTGACATGAGCTGGCTTCTGCTGCTCTGCTTTACAGGAGGCTGTGTGAT ATGTAGTTGGAAGGCTTGAATAGTGTTTTCTTTATGCTGAAATGGTCAGAGTTGGGTGAT GGTGGTGGTGGTGGTGATGATGATGATGATGGTGGTGGTGATGATGATGATGATGATGAT GATGATGATGATGATGATGACGACGACGACGACGACGGCTGCTGTGACCTCACTGTAGCC CCTTCATTTCTTAGGGAGGTAAAAAACAAATGAAAGCAAGCTGAGGGTGGCCACCTACTT AGTTGGGATTTGTGGATTCCTTGTTACTAAGTATCAGTTTGCAAAAGAAAGATCTAGGAA TAGGCTATCAGAAATCCAGACTTTGCATGTGAAACTGAATCTACAAATAGATTCCTGTAC AAAGAAGTGGTGGGGTCTACAGTGCATTCCAATGTCAGGCCTTGGACACTAGAGCACCTC CCTCACCTGGGGAAGGTGTATTCCCATCAGCTTTTGAAACACTAGGGTGAGTGATTGATG TATGGATGGGAAAACTTCTGGTGTTCCAGCCTTTCTGATGCTGGGACACGTTTAGGGGAA CATTTTCAAATCATCTCTGTCAGGGCAAAGTGGAATGAGACTTTTGTGTGGTCCTCCCTC CCTTAGGTTCCTGAAGCATCCTGGGTATTAGGAAGAAATAGATGCATTTGGGCAAAAAAG TTTCTATAACAAGAGGAAATATGTTCCTTAGCAGTCCCGATAGAGCTTGTCAGAGAAGGG AGTTTGGAAGGAATAGTGAAGCCAGATGTTCAACCGAGCACTGCTTCTGAGGCAGGTGGA GTGGTAGGCATCATGACGGGAACTCAGAATAGCAGAGGAGGAAGGAAAGGAGTCCTTCCC TCGTAAACAGTGGCAAACTAAATCCAGGTGCCAGGGAAATAAAAATGAAGAATCCAGGGC AGGGTGTTTCACTGGAAAGTGAGTGTTGAGGAGGGAAAAATGCCTTTTGTGAACAGAGAC TGCAGTGTGACCCATGACATCATTATTGCGGATAACCTAAAGAAGGTCCCTTCATGCTCT GTGGAGGGAGTGTCAAAGGTCAAGCCTCTTCTTAGCAAGGAATGCCCTCATCAGGAGAGG GATGGATGCCTGGAGGCTCCGAATTTAAAGCTCAGTTATATCATACATGTAGAGGTAAAA TGTATAGCCATGGAGGTACCAAGAGATCCTACCATCTCCACAGATGTACACCCAGGATGT GACATTTGTATGTATGCTTTAGGGGTCAGGAGTTTAGAGGAGTGGGGTGTTGTACCTGCA TATTAAAATACCATTGATTAGTCAATCCCCTCAACTGCATCTATGTCTTAGATAATATGG AATGTTAGGGGCTTGATCTGAGTATATTAAAAGCCTGAGTGTTGAAAGATGATGGATGTT CGCTTAGAATAATTTCAAGAGTCTTTTGAAGAATTTTTACCCCCATGCATATGTACAGAG CATAAATATTACTTCCACATCAACTTTGAAGCCTACAAATGCTCCCACAAACATTAAGTG AGGTTGTTTTGTTCATCAAGCAGATGATTGAAGTAGAAATGGAAAAGGCAAGACAATGTC CCTATAATAAACTTCGTTATATCTTTTTTCACTAGTGTATAGTGTTCCATTGTGTTGTCA TATGTTGTTATTTGTGTTCGTGGGAATTGAGTGATTTGCTTTTACTTTTGGCATATGGTT TGTGTATTCCTCTTTTCTATTTCTTTGTCTCTGTCTGCTGATTTGATTAGCGACCAAGTT CGTGGGTTATGGTATTATGCTTGCTTTTAATGATTTGTACAATAGTATAAATATTATTGT ATTTAATACTATGTGCAAAAGAAGCCTCAGGAAAACAAGAACAAGGCTGGGCTGGGTGTG AGATATATGGAAACACCAAGAGTACAATGTGTGCTTAATTCTGTCCTCTTCTCTCTTTAA GTATGGCTGGCGTCATGGTGGAGGTGGTAGTCTCAGAAACTCACCCAGAGCCTCTCAAAC AGGTTGAGTCATTTGCCGAATGCTGTGTCAGTTGTGGCCTGCTGTCTTTAGGTGTGACTG TTTCCGGAGATGCCAGAGGCAGTCCTGTCTGACACTGCATCTTGGGATTTCACAATCTTG ACTTGCATTATTGGGCAACTGCAACTCCGGAAGCAGATTTGTCCAGGACAAGGGGTGTGT CTACATGGGATTCAAATAGACGGATCTTTCAGTTCTCCCAACTGTCTTGTTTAGTGAATG TCAGCTATTGTATTTGGGGGGATATTTAGAGGTGCTGTATTTATCCACAGAGGAGGTGAC ATAGGCCAGAGGTGGAGTGAGGGGGGGAAAAAGAAGATTGGAATGAAATATTACTAATAA AAACTGCACTGGAAACTTAAAAGTGATTTAAAATTAATTTCATAAAGAAGTAGTCAAAGG TCACATGTTCAGGAGATCTTTGTGCATTTTGGATTGAAAGAAAAACTGGTAGAAGGGTTG AAGCTAGTAACAACTATTTGTTATTTAAGTTTCCTTAGTGTCTTTGCTTGTGAACACAGT ACCCTTGTGCTGGTACTCAAAGACTTAGAAATGCAACCAGTAAGCAAGCTGTCCTCTCTT GGAGCCTGGCTCCTAAATGAAGTGTAAAAGTAAGCAGACAGTATAGACACTGACAAGCAG GCTCATTTCTGCATAGCTAATGTTTCGGTGGCACAGAAACCATGCTCATTGGAACATATA ATTTTGGTTTTGAAAGGGTCTCTTTAACATTCCTCTCCTCTTTATTCACCTCAAGCCTTT TGACACTGGGCTTCTGCAGTGAAAAGTGGCTCTTTAAAGAGAGAAGAAGGCCACAGCCAG AGCTTGCCTGTCATTTGGATAAAACACAGCGAAATGATAGGGCTTTGAGCTTCATTCTCA AGGTGCAAGTCAAAAAGAGAATAACCAAAAAAAGGGAACTTAACCCAGAGGACGGAGTAG GCAGTCTGTTCTTCCAGCCTGATTTATTTGGCCCATCTGAATGGGGATGGTTCAAGCTCT GCCTAATGATTGTTTGGCCACGTTTCTAAGGATGTTGGTGTAGCCTGATCGTTATGTTAA AGCATTGGAAACTTCCTGAGAGTTAATAAGGCCATTTCCAGAGCTTTCAATGACGAAAAC GTTTGTGTAAATATTCTGCTGCATGCCCATCCCCCATTTTCATAGTTTGTTTCACTACTC ATCATGAGAGTGTGTGATATGTTATTCCAAAGCTCCTCTTAGGCTGTGGAAAGGAAATAA ACAAAAACAAGGTTAGCAGTATATACTGTATTTCCAGTTCACTTGATGAATGGTTCCGTG CTTCCCTTGGGTCAGCATTTTCCAGAGCTAGCCTTTTTCCTGAGTGCTCAACGCTGTCCC TAAGAGGGACACGTCAAGAGAAGCAAATTCCTGTATATGGTACACATTTATGCTTTTTTT CTCATGTTTACAAATGTGTCTGCTGTGACCTTTGAACTTGGCCCAGAGACGTCATCAAGC AGTAAGCTTGCAAAAGCCTTCCTCACTCCCTTAGCTGGCATTGTGTTCCTGTCCACTGAA AAAAAAATTTAAGAAAGGATGACCGTAATAGTGCAGATGAGAGCGATGAAGGTCACTGGT GACGCTATCACATCTTACGTGTGTCCTTTCTGATCCTTGCAAAATAAAAAGACCCTTTGG GAACATCGGAACTTCAGGACCAATTAGTGGAAATGATGCTTCTTGTGTTTGGGCATTAAA TACTAGGCAGGATTCTCTTTAGGCGGCTGATGCTGGCAGGGAAAGAGGTACCGACCTAAT TACTCTTCCGCAAGAGCAAAAAATGCCTTTTGAATGCCTCTTTGGCAAATATGTCTCATT AAGGACAAAAACCAAACACAACCCTCTAAGAAGCAGAAATTAAGATGATAGGTAACTTGT GGCCAGGAGACTTTCTGTGCCACTGTGGGAAATTAAAACAAAGTTTGGAAGTCCCAGGGG ATGACTTATTTTTGTTGAGTGTCTTTCCTGAAGCCTTGATGTTATTATGGGGCCAACTTT ATTTTCTTCATTATTTTGGCTCTGTGTCAGGGAATACTTTGCTCCTGTCTTCCATTGTGA AGACAGTGGGGTTTCTCCCATCCCATCTCAGCAGGATTTCTAACCAAGCAAATCAAGAAA TTCTCCATTGGGAATCCTAATCTAATGGAAATTTCATTTTCATAGTTATTGGCCAGAGAG TGGTAACGAACAGAAATGGGTTTTTAAAAGTTTTCGTTTTTAAGATTAAGTCTATTTTTT TTTGTTTTAGTCAATTTATCACTTATCAGCTTTTAGAAAAGATAGTGAATTTATGATTAG TTTTATGAAGCTAATAAAGACTGATTGCTGGTCTACTCACACTTGGGCTTGCATGTCATA GGTGTGAGTCTCTCTGTTACCCTGTCTGTCTCTTTGTCTCTCTATCTCTCCGTGTGTGTG TGTGTGTGTGTGTGTGTGTTTATTTTGCAGTGCTGGGATTCAAACCCATGGGTTTATGGA TGCTAGCCAAGTGCCCAGCACATTACTAGTAGCATTAATCTTGCCTGTATTTTCTCTGGA ACCTTCATGTACAAGGCAGTCATATATGACTTCTTAGTGTTTACCGGGATTTCACAGCTG CAAAACAAAGTAAAGAAGATTGGCCGCATTTCTTTTATTTGCTGGTTAGCTGAAATGATT AAGAATAAATAAATGACTTTAGTTTTGCCTACAGTAGGTCTCTGGGGAAAGGGCAAGTTT TCCACTTCTGACTCTGTATGCTTTAGTGAGTTTGTCCATCGCCTGACTATGACTACATTC ACTGCAGGTCAAGGTTGCTATTCGGTGTAAAAGTCTTCCTTGACCCAGGATTATATCAAC CAGCATGTATTCAGCAATTTACTCAGCAAAGCTTTTAAAATGTACCCTTCCCAGACTAAC CAGGAGCATTATGAGTTTGTCAGCTCCCTCAAGTTTTACATTTAGAGTGGGTGAGACTTG TCCTCCATTTTTCCAAGGTAATCTGGAACATAAAATTTCATTGTTTTGCAAAGAGTTGTG ACACAACTGCCCATGGTCTCTAAGAAGTCACATGCATTTAAACATTCTGAGGAAATTAAC TGCAGGTAACAAGAGATCACCTGTAACCAAAACATCAGATCGTTCAGGTGAATAGTCAAG AAGAACACAAGGATCAAAAGGTCTGTTTGGGTGAGAGCCAGGGAGACACCGGCCTGTTCA TCAAGACCACACAGTTGTTAAAAGGGTTCGATGATGACTCCATATTACAGGTGGATTATT TCACTGGGATGCAGTGCAGAGATGAATTTCCCTCCGTGGGTTTATGACCTCACAAGAAGT CTCTACAACACACTCCTCAGAATGCATCTAGAGCTTCTTGTAACTGGCTGTTGAGGAGAA CTGTACAACCAATATTGTTCAAAGCAGTCCTGGAGACATTGTGCTATCAGAGGGGAGTCA GATCCTGATTTGGGAAGTGTATCTAGAGACACCAAGACTTTAAGGTTCATGACATGCTTC AAATGTGTGCCTTTAAGTTTAATGTGTAGTTTAGCACTTCAAAGACTAGTGGAGTTAACA ATGAGATTATCTGGCCATAGGCAAATTATGATATTTCTCTATCTATTGTTGATTGTAAAA TGGCTAAGATGATTCATGTAAGTAACTTACTTCCTGGTTGTTACTGAATCAAAATATATT ATTTAAATCACATCTAAGAAGGAAGTTCGTGATTTTAAGATTACTTTTGGACAATGAATA GTATCTATTTCACACCTGCCCTGCAAAATGTTTTGAGAAGGTACAAAAGGAGCTTTGATT CTTTCTCAAAGTTAAAATAGCTATGTTGTAACACTAAAGCGCCTGAATGAAGCCCATTGA GTGCTTTACATCAGTGTCCGCACTGCTCTCCTGTGATTCACTTTTAAGTAGCTTCAATTA ACAGCAGTTTTATATGTGACTATTTATATGAGAGAAGGAAGTCGATCCAGTCAGAAGAGT TTTGTAATATTAAGGGTAGTGTATAAAAATCAATTGTACTGTTGTAAGCTGTCCCTAATG GTATTAGCTTTGATTAAACCATCCTAGAGGGAAATCCAATTGTGTTAATTCAGAATGAAG TAATTGGCTCTTTTTTGTTGCCTGTCTTTTATTATCAATTTACAGACCCAAAGGCTCCTA ACTTTCAGAATTCTACATTTAGCTATTTAACCCATGTGCCGAGGGGGTGCATGGAACAAT TTTAGTCAACATGCCTTGTATTTGAATACTTACTGTCTTGGGAAGGTTGTTAATCACGTA TATGGTAGGAAAGTCCATGGTTTGTTTGGGTCTTCCTAGATAACAGTGAGGGGAAAACCC CAAATACCCCAAGAGAGAAATTTCTTGTCTGATTTTTAGAGGCAGTTTTGAGGTTAAAGC TACAGCATGCATAATGTAAGCAGTAGCCACAGGAACCTGGAGGGGTCGCACCATGCAGAA GATCTCTTCACATAAATCTCTTCACAGAGCATAAATCTCTTTTGCACAGAACAATTTGCC CATTTTATTTTAAACCATGAACATAGAATTTCTCCAGAGGAGCGGTAGTGTGCCTTACGC AGTGGGGTAATGCCTGACAGTGACAGCTCTTATCTATACACTGTCATGTGTAGAGTCCCT GTCCTTATCTAACTCTCAAGGAGCCACATAAGGAAAGCAGTCACGATTACCAGCCTTTTC CAGATGGGAAAGCACTGACCAGAGCAAGTGAGAGGAGTCATACTTAAAAATAATGGATTA TAGATTGTCCAGCTCTGCCCAGACACAGAACCCACTTGTATCCTAGTCCATTGTTTGAGA TTAAAGAACTTCGATTGGGTTGGTGAAATGGTGCCCTGTGTAATGTTCGCTGCCAAGTCT GATGAGCTGAGTTTGAATTTCAAGGAGCCACATGGTGGAAGGAGAGACCTGACTGCAACA AGTTGTCCTCTGCCACAAGTGTTATGACACACACACACACACACACACACACACACACTA CAGAGAGATAGAAAATAAATGAAGAAAGAAAGAAATGAAGTTATTATTTAAAAGAAGGAA AAGCAAAAATAAATTAAGCTCGTGTGTGAAAACTCCAGTCTTTCGTGAGTCTTTTAGAAT TCAGAAAGAGACATTCTATTTCAAAAACAAGATAATTTGTCTTAAAGTGAACCATTTAGT TTTAACTTTTAAAATGATCAATTAATCATTCATTCTATAATGCTTGCTAAGCATTGGCAG AAAAGTGAGAATAGCAAAAAAAAAAATTACCAGAATCAATTTATTTATGAAAATAGCTAA CTATGGTATCTTCAGAGATGGGAAAAAATTGCCTCTGATGAATATTCAGAATGAAAGACT TATTTTCTTTTGACCATCCTTTATGTTGCCTGATACGACTAGTTTTTACTCATAAATATA CATTACACACACACACACACACAGACACACACACACACACACACACACCCTTCCCATTAT ATTTACAGTAAATTGCAGCAGCAGTATGTTTGTGTGGTCATTCTTTTATCTTTCTTTTTT TCTCACTATCAGGTTAAATTGGGTGAAGATGCTCCCAATTCCAGTGTGGTGCACGTGTCC AATCCTGAAGCAGGTAACAATTGTGCCTCAGAGAAGACGGCGGATGGGGCTGAATGCCAC CTTCTTGACTTTGCCAGTGCAGAGCGCCCACTGGTGGTCAACTTTGGTTCAGCGACCTGA CCACCTTTTACTAGGCAACTGCCAGCCTTCCGCCAGTTGGTGGAAGAGTTCTCCTCGGTG GCTGACTTCCTGTTGGTATACATTGATGAGGCTCACCCTTCAGATGGCTGGGCAGTGCCT GGGGACTCCTCTATGTCTTTTGAGGTTAAGAAGCACCGGAACCAAGAGGACCGATGTGCT GCAGCCCACCAGCTCCTGGAGCGTTTCTCCTTGCCGCCCCAGTGTCAAGTTGTGGCTGAC CGCATGGACAATAATGCCAACGTAGCTTATGGGGTAGCCTTTGAACGTGTGTGCATCGTG CAGAGACGGAAAATTGCTTACTTAGGAGGGAAGGGCCCCTTCAGCTATAACCTGCAAGAA GTCCGAAGTTGGCTGGAGAAGAATTTCAGCAAGAGATGAATTCTAGATTAGCTGGATAAA AGTGTGATTGTAATAGAGTTTATTATTTTAAAAGAATGTGTAAAAGTTGAGAACTGAACT GAATCTATTATTTCAACGGAATCCCATCGCCTCACTGAAAGACGGGTCATACCTGTCAGA AGATCTTGAACCTCTTTAACATCTCAGTACTTCCTTTAGTACACAAACGGCATCTGGTTA AACAGCAGCCCTGTTACCTACTTTCAGAGCTAACTGGTCCAAAATGGAGGGCCAGAAACC CCGTTGCAGCCTTGTTCATTCTCGCTTGTGAAAGAAGTGATGCTGCCCTATGTGTGCTCT GGGACTAGAGGACAAAAGTTCCCAGAAAACCTATTGTTAAGGGAGCTACTACCTATGATC TGATTAAGTGTATTGTCTCAGTCAGCTTTAGTCACCAGAAGTAAACCCAACTGGAAAGTC CCCCCAAATACATACTTATAATGTGA