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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DGCR8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID54487
Official gene symbolDGCR8
Full nameDiGeorge syndrome critical region gene 8
Aliases,C22orf12,DGCRK6,Gy1,
Gene summaryThis gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q11.2
Gene position20067755 - 20099400  Map Viewer
Gene orientationplus
Gene size31646 bp
Gene sequence
OMIM ID609030