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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for OAZ3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID51686
Official gene symbolOAZ3
Full nameornithine decarboxylase antizyme 3
Aliases,AZ3,OAZ-t,TISP15,
Gene summaryOrnithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q21.3
Gene position151735445 - 151743806  Map Viewer
Gene orientationplus
Gene size8362 bp
Gene sequence
OMIM ID605138