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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DUOX2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 50506 Official gene symbol DUOX2 Full name dual oxidase 2 Aliases ,LNOX2,NOXEF2,P138-TOX,TDH6,THOX2, Gene summary The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. [provided by RefSeq] Location Chromosome: 15   Locus: 15q15.3 Gene position 45406359 - 45384852  Map Viewer Gene orientation minus Gene size 21508 bp Gene sequence >DUOX2:complement(16175409..16196916):Length=21508 GGTCTGTCCTGAGCCGACACCTGCACAGTGGCGAGACCAAGGACCCAGAGAGAAAGGTGA GAGTGCAGCCGGGGAGGCTGAGGATCGGCGGAGCTGGAAGAGTGAGGGTGAAGGCAAGAA GTAGAGCACAGAAGCAAAGATTTTAAGAGGAAAGAAGACATCTGAACCCAACACCACCCT AAACCACAGGTTAGACCAGAGTTTGGGATCTGACCCTAGCCCTCGCCCATCATGCACAGG CGTTCATTGCAGAAGGGGAGTTTATTGGGGAAGGGGGGATTCATTGTGGAAGGGTGCTGC AGTCCCTCACTCCCAGGTCAGTAACCTTTTTCCCTTCCCTGCCTCCTGGAGGAGAAGCGG AGCCTGACGGATCGGGGGCGGGTGGAGGTGAAACATTGGAGACATTGGGCACACCCTGGG AGGCTTGACCAGTCCTGCCCTGGACTGACATGCCCCAGAAGACTCCTGCCCAGTGGGTTC CTATGGTCGGGGGTTAACTCTCTGATGGGGTGGCGGATGGGGAACAGTGTCAATGCCTCC AGAGCTGCCAATTGTCCTGGAAAGAGTGGCGTTTGGATGAAGGTCCTCGGTGATGCTTCT AACAGCTACCTTCCAGAAGTGGAAACAGCTGGTGCTCCTCCTCCAGTACTAGCTGTAGGA ACAAGAGGGGAGGCATAGAGGACGCCCTAACAGTGGCTTTCGCATACCACCTACCACCCC CACCCTCACCCCGCAGGCTGCAGGGTTGGCATGCTCCGTGCAAGACCAGAGGCACTGATG CTCCTGGGAGCTCTTCTGACTGGATCCCTGGGTCCATCGGGCAAGTATCAGGCTCCTCTA GCGGCGGGGTGTTCCCCAGGATCCCTGGGAGGTGGGGCGGGGAGAGGTGCGGCAAGCGGC TCCCTGAGACTGGAAGGTCATTTCGCCGTGCAGCTCAGCGGGATGGGAAACTTCCCAGTG CGGCCCGACACTTGGGTCCGGTTAGGGGCGCTCCGCGAGCTGGGGAAGGACTGGCCAAGG CCTTCGTTGCTCGGGAGGGGTAGCTGGGAGCGTAGTGCTGAGGAGGCCCTTCTCTGTGCC CACAGGCAGTCAGGACGCACTCTCACTGCCCTGGGAAGTGCAGCGCTATGACGGCTGGTT TAACAACCTGAGGCACCACGAGCGTGGTGCTGTTGGTGCGTTCTGGGGGCCCGGGCGTGC TGGGGCCGTGGCTCGCGAAGGGCCGGGGCGCGAAAGGCCCTGAGCGGGGAATCTGCGGGG AACACGCGCCCAGCAGCTCCGCTGCCTACACAGCGCAATCTTATGCGCTCCCGGGGCCAA GAGACCCTTGAGGGAAGGTTCTGTCAGTGAAGTGGGATGGGGGTTGAGGGAGGCTTAGGG AGAGGTTTGGGGGATCCTAGGGGATGGAGTGCTTAGACAGAGCCCCGCTCCCTGCCTCCG CAGGCTGCCGGTTGCAGCGCCGCGTACCAGCCAATTACGCCGACGGTGTGTATCAGGCTC TGGAGGAGCCGCAGCTGCCCAACCCGCGCCGGCTCAGCAACGCAGCCACGCGGGGCATAG CCGGCCTGCCGTCGCTCCACAACCGCACCGTACTGGGGGTCTTCTTTGGTGAGGGCAAAG GGGGAGACCAGTGGGGTTGATCTGGCGCTCTGCTCAGCCTGGGGGAGGGGCCAGATCCCG TCTGCGAGTCCACAGGAGACCCATCCGACTCCCAACCACTTCCTCTCTACGCAGCACTTC GAGACTGCCTTCATCTCGGAGAGATTTTGGGATGTTGATACAGAGATATTTGCTCTGTAT CTAACCTTTCTCTTACGCCTTATTCCAACCTAGGGGTGTCACTGGACCCCCATTATAGCT CTTGGGAACTGAGCTCCCCAGCCACCGCTCTCCTCACCGTGTGTTTGTAACCATTTTACC TCCCCCTAGCCCAGAGGGAGGAGGACTGACTTGGGGTACCCCTACATAAATTATATCATT TTGATTCTCACAACAGCTTTATGAATTGAGTAGGAAGGGAACTCACTATAGTCTTACTTT GCAGATTAGAAAATTGAGGCTACCTGGGGCTAACGTGCAGAGCTGGTGGCGGAGCTGGCA CTGGGACCTCTGTCTTTTGGCTCCTGAGGACACTTGGAGGCCGCCCTGGCCGTGGGGAGG GCGCAATACGGACGGTTTGTCACGTATTGGCGCCCCATGCCCGCAGGCTACCATGTTCTT TCCGACGTGGTGAGCGTGGAAACGCCCGGTTGCCCCGCCGAGTTCCTCAACATCCGCATC CCACCTGGAGACCCCGTGTTCGACCCCGACCAGCGCGGGGACGTGGTGCTGCCCTTCCAG AGGAGCCGCTGGGACCCCGAGACCGGACGGAGTCCCAGCAACCCCCGGGACCTGGTGAGG CGGGGAAGGCGGCGGGAAGGGACCGCACCCCAGCCAGGTGGGGCCTGGGCTTCGGGCCTG GCAGGGCCTGGAGGGGAGAGGCGCCCACTCCCCAGCCGCGGACACCCGCCGGGCCCCGGC CTTCCCTGGCCCGCCGCCGCCTCTCGACCCGGGCTCACCCGCCGCGTGCCCCGCAGGCCA ACCAGGTGACGGGCTGGCTGGACGGCAGCGCCATCTATGGCTCCTCGCACTCCTGGAGCG ACGCGCTGCGGAGCTTCTCGGGGGGACAGCTGGCGTCGGGGCCCGACCCCGCTTTCCCCC GAGACTCGCAGAACCCCCTGCTCATGTGGGCGGCGCCCGACCCCGCCACCGGGCAGAACG GGCCCCGGGGGCTGTACGGTGAGGCCACAGGGGCGGGACGGGGCCGGCTGGGGGTCTGCG AGTGTGGGCTCCCCCGATCACGCTACCGCTCGTCTCCTCCCCTGCGCCCCCACGTCGGAT GCAGCCTTCGGGGCAGAGAGAGGGAACCGGGAACCCTTCCTGCAGGCGCTGGGCCTGCTC TGGTTCCGCTACCACAACCTGTGGGCGCAGAGGCTGGCCCGCCAGCACCCAGACTGGGAG GACGAGGAGCTGTTCCAGCACGCACGCAAGAGGGTCATCGCCACCTACCAGGTCAGCCGT CCGCGCCCCGCGACGTCCTCCCTTCCGCGTGCAAGCCCACGGGAGACTCCGCTGCCCCAT GGAGCTCCCCATCTGTGGACAACCGCCACCCAGAAACCCCTCCCCAGACAGCCGAGGTCT AGGGAAGCCCCTGTAAATGATAGGGAGGCACGCGCTGTTTATAGGAGAAATCTGGCTGGT GATGATTATTTATCACCTCCCCAACCCCCACTCCCTCAAATCCCCTGGTTCCTTGTGGGG ACAGGCCTCACACTGCTCCTGTCTGAGTTGCTTCTCCCATGATTGACCCTTCCTGGTCTC ATCTCCACACGGAAGCCGTCCTTGGGCTCAGACCCTTCCAGGCCCCACACCATCCAACTT GTGCCTCCCCTCGCCCCTCTCTGCCCCTCAGAACATCGCTGTGTATGAGTGGCTGCCCAG CTTCCTGCAGAAAACACTCCCGGAGTATACAGGTGAGGGAGCGGGGAAGGAGGACACCTG TGCGGAGAATCCTGAGGGGAAGGAGACAGGTGCCTGTGATGGGAGGATGTGGAGGCAAGA AGCCTGTCTCCCCATCATCACCGTCTCCTTCCTGCAGGATACCGTCCTTTCCTAGACCCC AGCATCTCCCCGGAATTTGTGGTGGCCTCTGAGCAGTTCTTCTCTACCATGGTGCCCCCT GGTGTCTACATGAGGTGAGGGAGGGGTTGGCAGAGAGGGGCACCACACTAAGAAAGGTGC AGAATGAGCTGCCTTGGGGGCTGGGGCCTTTCACACTCCTTCGCAGTTTCACTAGAGAAG GGGAAGCAAAAATTTGGGGCCCTGAAACAGAACCCTGGGGTAAGATGTGTAGGCTTAGTA GGGAAATCTCTCCAGCTCTCCTAAGGGCTGAAATTTGGTGGCTGGGTGTAGGATTTGTCT AGCAGCTGGGTCATTCCCTTCCCTCCTCTCCCCACCCTACCTGGACTAGGAGCGCACTCT ATCTTCAGTAAACGCACATCACCAAATCTCTGCCGTGTTCAAGGAAGTTCCTGGGCCACT GCTCAATCCTAGTGAACCCCCACTGAGTCCCTCAGCCCACTCAACCCCATCTTTGATTCT TCTCCAAATTCCCTCACCACATCCTTTGTTCTCAATTTCAGAAATGCCAGCTGTCATTTC CGGAAGGTCCTGAACAAGGGTTTTCAAAGCTCCCAAGCTCTCAGGGTCTGCAACAACTAC TGGATTCGGGAGGTCAGACTGGGGTCAGGGTCAGGGGAAGATGGGTCAAGGTCAGTCTCT TCACACAGGCTGGGAAAAGCAACAATCCCAGTTCTTGAGTGTTGCTGCCCCAGGTTCATG GGAGATGAAGGGTAGAGGAAATTATCCGGGGACAACAGTTCAAGAGAGTCTGGGACTGGC CAAGGGCCCTTTGTCCTGGGGTACTAAAGTGGTCCAGGCTGAGAGAGACCGAGTTTTGGG TAGAGGCCTATCTTGAGTGCATTGTTTACTTCCAGAACCCCAATCTGAACAGTACCCAGG AGGTGAATGAGCTGCTGCTGGGAATGGCCTCCCAGATTTCGGAGTTGGAGGACAACATAG TGGTTGAAGATCTGAGGGGTGAGCTCAGAGCCAGAAGGGGTGGATGGTAAGGGACCAGGA AGCCTGAGGATCCCTCTGGGTTCATCAATAGCAGACCTAGGGCGCTCACGATGCAGGAAC ACAGATACAAACACAGACTTCAAGGAGCCATAAGAAGAAAATGAACTTTGAACTTTTTTT TTTTTTTTGCTTAATTTACACTTTTGTGTTGCTTTTATTTTAAATTAACTATGTCTGAGT ATTGGGGAGGGGTGGTACCACAATCTCTTTGGTGCTTAATTAGGTCTCTAAAGGTTTTCA TTCAGCCCTGTCTTGAAACTAGGGAGGCATAGGACAGGGAATTTACTGCTTGGTGACTAG AACAGTCTTGAGTCTTAGAGGAAGGGTCTTACTGGAAAAACTGGCTCTGATCACCCATGG TGACATTGGCCTTGCAGCAAGGCAAGGTCAGCATGGGCACAGATCTCATGTGGATCACTG GGGGTAGCCAGGAGGGAAGAACCGTAGTGCCAATAGTCAGATACAAGGCTGCAGGGCAAA AAAGGATGGAGAGGACAAAGCCCATAGTCTAGTCTTCTCTCCTCTTCAGATTACTGGCCT GGCCCTGGCAAATTCTCCCGTACAGACTATGTGGCCAGCAGCATCCAACGTGGCCGAGAT ATGGGGCTGCCCAGCTATAGCCAGGCCCTGCTGGCCTTTGGGCTGGACATCCCAAGGAAC TGGAGTGATCTCAACCCTAATGTGGACCCCCAGGTCAGGAATAGTAATGATAATAATGGC AGCTAAAGCTTTCCTATGGCAATACTGTTCCAAACCCTTTACATATGTTGACTCATTTAA TCTACATAATAATATTGTAAGGTATGTATAATCATTTTCCCCATTTTACTGATGACATAG TTGGTAAATCATAGAGGAGGGACTTAAATTCAGCCATCTGATTCCAGAATATATTCCTAA CCACTGCATTGTACCATTCCTGCAGGGTGGCTTCTGGGTTGGGTGCCATTGTCCTGTTGC TGCAGGGTCCCACCCCAAGGGCTGTGTGCCCCTGAAGCTGCTAATCATTGAGGTCAGGCA GGCTGGTGATGGTCACAGGATATGGTCCTAGGGCACCTGACCGTGGTGTTACCGTGGGTA GGGACACACTGATCCTTCCACCAGACTTGTCCTGCCTGAGGGGGCTTGCCTAAGAAGAGG AAATCAGGCCTGAGCAGCAGCCAGGCAGCGGCTGAGGTTCTGTGCCCGAGGGATGGGGCA ACAGTGGCTGCCCTCCGCAGCAAACATACGCTCACCCCTTATCTCCTGTGGTGCCCCAGG TGCTGGAGGCCACAGCTGCCCTGTACAACCAGGACCTATCCCAGCTAGAGCTGCTCCTTG GGGGGCTCCTGGAGAGCCATGGGGACCCTGGACCCCTGTTCAGTGCCATTGTCCTCGACC AGTTTGTACGGCTGCGGGATGGTGACCGCTACTGGTTTGAGAACACCAGGAATGGGTAAG GCTTGCCTGGGCCCCCACCTCAGACTGCTCCTCAGCCTGAGCCCCAGACCCTCTGTCTAG CCTTAGACAGCCCCTATGAGCCCTTGATTCCCAGTCAGCCCACCACACCCTTCCCAACCC CTCTGGGTCTCTCTTTTTTTCTTCTCTTCTCTTTTTCTTTTTCTTTTTCTTTTTTTTTTT TTTTTTTTTTTGAGGCAGAGTCTAGCTTTGTCACCCAGGCTGGAGTGCAGTGGCGTGATC TTGGCTCAATGCACCCTCTACCTCCCAGGTTCAAGTGATTCTCCTGCATCAGCCTCCCAA GTAGCTGGGATTACAGGCATGCACCAACATGCCCGGCTAATTTTTTTAAAAAATATTTTT AGTAGAGATGGGGTTTCACTATGCTGGTCAGGCTGGTCTCGAACTCCTGACCTCAAGTGA TCCACTCGCCTTGGCCTCCCAAAGTGTTGGGATTACAGGCATGAGCCACTGCACCCAGCC CCTCTGGGTCTCTTTTCTCACCTGGGTCCTTGGGCCTGGGGTTGCTGGAGGCCTGCATCC CCTTCCCATCCCAGTGACTTCTACTTCCTCCAACTTAGGCTGTTCTCCAAGAAGGAGATT GAAGACATCCGAAATACCACCCTGCGGGACGTGCTGGTCGCTGTTATCAACATTGACCCC AGTGCCCTGCAGCCCAATGTCTTTGTCTGGCATAAAGGTGAGTGCCGTGGGAGAACACAA GTGAGTGACAGTGGCCAGAGAAGGATCAAGATTGAGGGTGCGGGGGAATCACTTGGTGCT GTCCAGGGAGCCAGGCACCTTCTGTGTTGGGCTAGGAGGCCTGCATTTGGCTGGCTCCCA CAGCAGGGACCTCAACTAGCACACAAGCTACACCCTACAGTCAAGAAGGGGTGGATGGGG TAGATGCCAAGAGACAGGAAATGAATGGGGACTTTTTGAGGGAGACAGTTTCAGGGAGGT GGGCCTGGGGAAGACAGATGATACCTTGGTCCTTTATAGGATAGAGGGGAAAGAGGTCTG GCCACATAGCGGGATCCTCAGACTTTGAGGTCTTCCCTGCCCTCTCCCTCAGGTGCACCC TGCCCTCAACCTAAGCAGCTCACAACTGACGGCCTGCCCCAGTGTGCACCCCTGACTGTG CTTGACTTCTTTGAAGGCAGCAGCCCTGGTTTTGCCATCACCATCATTGCTCTCTGCTGC CTTCCCTTAGGTGAGCTCTTAGGCAGCCTCTCTGCAGACTGGCCCTGCCCCTCATTTCCT GCTGGCCTGAGGGGCTGGCTATTTGGTACCGTTTGAGACCAGGCTCAAGGAACCTCTGGA AGGGAGGGGCCATAGCCTAAGCCACAGTGGAGCTCTAGGTGAGGGGCTCCCTCCTCACTG TTCCTTCTGATCCACTTCAGTGAGTCTGCTTCTCTCTGGAGTGGTGGCCTATTTCCGGGG CCGAGAACACAAGAAGCTACAAAAGAAACTCAAAGAGAGCGTGAAGAAGGAAGCAGCCAA AGATGGAGTGCCAGGTGAGCAGGGGCTGGGCAGAGGAGGGAGGAGGGACGGAGGAGGGGA GAGACAGGAGTCTGGGAGAAAGAACCAAGTTACAGAGTGAGAGGAAAGCCAAGGCACCTT TAGGGCGCCTGCTCAGACTCACAGAGGAATTGACCTGAAGGCGGGGACCTGGGGACATCT GCTGAACTACCCGGCCCAATTATCCCTTCCCCAGCGATGGAGTGGCCAGGCCCCAAGGAG AGGAGCAGTCCCATCATCATCCAGCTGCTGTCAGACAGGTGTCTGCAGGTCCTGAACAGG CATCTCACTGTGCTCCGTGTGGTCCAGCTGCAGCCTCTGCAGCAGGTCAACCTCATCCTG TCCAACAACCGAGGATGCCGCACCCTGCTGCTCAAGATCCCTAAGGAGTATGACCTGGTA TGGCTCGTCCTGCCTCCCCAGCCTGGGCTGCCCTCACACGACTCCATTATCACAAGCGAG GCCACCCTATCCTCAGCTACAGAGCTCAACTATGACAGCTGATGCTGGGGAGAGGGGCTC CTTTCAGAGGCCCCCAGACACAACCTGACCCCCTTCGTCCACACACCTGGCCCCAGCCTG GATGGATGGGGAGGAGTTTTCTCTCCTCCCCTCAACCCAAGATCCATTGAGGGGAGGCTG AAGCAGAAGGTCCAGCGAGCTCCCTGCGTCAGTGCCGCCTTCCTCCCACCCAGGTGCTGC TGTTTAGTTCTGAAGAGGAACGGGGCGCCTTTGTGCAGCAGCTATGGGACTTCTGCGTGC GCTGGGCTCTGGGCCTCCATGTGGCTGAGATGAGCGAGAAGGAGCTATTTAGGAAGGCTG TGACAAAGCAGCAGCGGGAACGCATCCTGGAGATCTTCTTCAGACACCTTTTTGCTCAGG TGCCATGACCTGTGCCTTTTGGAGATGGGTCCAGCCCCAGAAATGGAGGAAACCTGGGCT GCATAGAACGCCCCTGTGGGTGAACTAAGCTTCCGCTCTATGGCCTGGAGAGAAATAGCC TTGTTTGAATCCTGGCATTGCCACTTTACTTAGCTCTGTGACCTTAGGCAAGTCACATTA TCACTGTTCTGTATCTCTGTTTCCTCATCTATAAAACAGTGATGAAAACTGTATCCATCC CATTGCATTGTTGTGAGGATTCGGTGAGATCGTCTACATGAGTGGTACACAGAGGTTGGC CTCTGGACCCGAGAGCATCAGCCTCACCTGGGAACATGTTAGAAATGCACCTACCCAGTT AGACTGAACCAGGAACTCTGTGGGTGGGGCCTGGCAATCTGTGTTTTAACAAGCTCCCCA GATGATTCAGATACACTCTAATGTTTGAAAAACATTGTTTTATGTACAGTGCTTATTGGC CCAAGTGCCAGGTATGTTGCAGGCATTTAACAAACGGTTGTGGCCAGGCGCAGTGGCTCA TGCCTATAATCCCAGCACTTTGGGAGGCTGAGGCGGGCAGATCACCTAAGGTCAGGAGTT CGAGACTAGCATGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCT GGACGTGGTGGCTCACACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGC TTGAACCCGGGTGGCGGAGGTTGCAGTGAGCCAAGATCATGCCACTGCACTCCAGCCTGG GTGACAGAGCAAGACTCCATCTCAAAAAAACAAACAAAAAACAATAAATGGTTGTTACAT GCGACTTTTAAACTTTTTGTGCAATGGGCAAATCATAGGCACATGGCAGCCTTATCTGAA TTGGCAAGAGAGCACAGCCCCAGCCCCTTCCTGCCTGTCTACCACCATGTCTCTACATCT TCTGTCCCCAGTATAGGCTCTCTCACTTTCCATTCCCCTTAACTTCGCCCTTCCCCTTCC CTACCCCAGCACCATGCCCACTGCATGAAGTTCCCGGTTCTTGGGCCCAGGGAGAAATGG GCAGGCTGCTAGAGATTTGATTCCCCCGTCTATAGGACAACAGAGGCCCCAGTCAGTATA TCTAAGGATCAGGAGAACCATCAGAGTTTAGCCTTTCTGATTTGGACTTTGGGGAGATAT GAAGGGTCACTGAACTGCTTCCAGCATAGGCTTCACCTCCTTCTCTTTCCCTCCCTCTGC TGCTGCCCGAGTGCAGGTGCTGGACATCAACCAGGCCGACGCAGGGACCCTGCCCCTGGA CTCCTCCCAGAAGGTGCGGGAGGCCCTGACCTGCGAGCTGAGCAGGGCCGAGTTTGCCGA GTCCCTGGGCCTCAAGCCCCAGGACATGTTTGTGGAGTCCATGTTCTCTCTGGCTGACAA GGATGGCAATGGCTACCTGTCCTTCCGAGAGTTCCTGGACATCCTGGTGGTCTTCATGAA AGGTAGGGGGCTGGGAGGTGGCAGGCTATCCAAGAATCCAGGGGTCTTTCAGCAAGGAGA TGACCTGCATTCCCTTTTTTCTTCCCAGGCTCCCCAGAGGATAAGTCCCGTCTAATGTTT ACCATGTATGACCTGGATGAGAATGGCTTCCTCTCCAAGGACGAATTCTTCACCATGATG CGGTATGGGGTGTGCCTTTCTAATCCTGAGACTTCCTGGTGTGTTTCAAACAGGAAAACA GGTCCAGTCAGAGGAGGGCTGGCAAAGAGGCTCTGTGGTCATCTGTGCTGAGAGGTGGCC TAAACACTACATCCTAAACTCTCAGAGCATCCACCTTCAAATATTTACCTGACTGGCTCC TGCCTCTGGGAGAGTCTCTGTCTGGACTGTCAACACCAGCCAGAAAAGCCTCCCTAGTTA AAAAACGAAAAAAAAAAACCCAACACCAATATGGCCAACGACAAAAATCCACTAATCCCT TTTGGATGCCCTTGGATCTTTGTGAACTATTTTACGGCACGCCCAACACCGTGCTCTACC CAGTGAAACAGTGAATGGATGACCTTGGTTGCTGCTCCGCTATTCATCACCATGATAGTC AGGAAGAGAAACGTGGAAGGCTTCTCCATATTCCAACCATTCTTTCTTCCTGCATCTTAA GCCCTTTCTGGTTTTGTTGTGCCGGTAAAAAAAAACAGCTTTGTGCTTCTCATTCCTGAA GACAATGAATGCGTCAGTAACACAGCTCCCCTCCATGCCATAAGGGCAGGGCTTGTTCCC TGTTGAATCCAGCTTCTCTACACTGTGATTGGCACAGGGCAGGCATTTCATACATAACTA ACTGAGTAAGACAAAATGAAATAAGTGAGCAAATGAATACAAAGTATAGATGTAACAGCC CACATTATTTCAATTTTTCTATCCTGTTAAGCCTTAACATTGCTTTAAGCATTCCCCTTA ACTGCTACATTCCTCATATGGTCCAGATACCCCAACTGGACAAGGGCTTCTGAAAGGGCA AAGCTATTGCAGTCTGTACCTCACTGGGTATGTCACTGCAGGCCCAGCCCGAGGTGAGGC TCAAGGGAATCTAGGAGAGGGTCCCTGCCTCCAAGGGCTGAGTTCCCACCTTCTTTTTTT GGTTTGTTTGTTTGTTTGTTTTGAGACGGAGTCACTCTGTCACCCAGGCTGGAGTGCAGT GCCACGATCTCGGCTCACTGCAACCTCCACTGCCCAGGTTCAAGTGATTCTCCTGCCTCA GCCTCCCAAGTAGCTGGAATTACAGGCATGTGCCACCACGTCCAGCTAATTTTTGTATTT TTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTAGTCTCGAACTCCTGACCTCAGGG GATCAGCCCGCCTCAGCCTCCTAAAGTGCTAGGGTTACAGGCGTGAGCCACCACACCTGG TGAATTCCCACCTTCTTGTCCTGTAACTCAGCGTGTATCTTGCTTACTGTCGGTGGGACG ATGTTTTTAATGTGATGGTTGTGCTTGCTGTGTTTTATGGGCCCAGCATGGCACAGCATT GCTGCCGGACCTACACAAACTTGCATAGTCTGTCTTTTCTGTCCCGAGGCACAACCTATG AATAGAGCTTGGCTACTGCAGGTGCCACTGTGGGTGCTATCAGGTTGGGCATGGAGACGC TCCCGCCTGTGCCCCGGGGTGTTGGCACAAGGAAGCAGCAGCATTGCAGCTAGTTCCCCT CCCTGGCACCTGGCTGCCTGGTGCCCCCACTGGACTATGAAAGGGGGAATCCAGGGGTGA TGTGGGAGGCATCAACAGAAGAGAGTGGACAGAGAGCCTGCCACGAGAGAGGGCCATGCA CACCCTGGACACCCCTGCACTCAGTGGACTATCTTCTCAGTTGTAGATGCCCCCTGTTTG AGGGCTGCTTTCTCTGATTGGTCAAGGTCACTTTCAATTCTGTTCTGCCTTTTGAGTCCA TGGCTACCCCACCCAGCTTAGTGTCAGCGGCAGGCTGGATGAGCACCTTCTCAGTGCCAT TTCCCGGGTCACTGGTAACCACATTAGATAATCTGGGGCCTGCCCCACCCTGCACCTACC CAAGCCTGACCTTGCTGGGTGACAGGCTGCTGTGTCTCTGGTCCTCCTCCAGATCCTTCA TCGAGATCTCCAACAACTGCCTGTCCAAGGCCCAGCTGGCCGAGGTGGTGGAGTCTATGT TCCGGGAGTCGGGATTCCAGGACAAGGAGGAGCTGACATGGGAGGATTTTCACTTCATGC TGCGGGACCATGACAGCGAGCTCCGCTTCACGCAGCTCTGTGTCAAAGGTGGAGGTGGAG GTGGAAATGGTGAGTGTGTGAGGAATGGTTGGCGTCAGGGAGGGGGGGCGTGTCCTCAAA ATGAGAGTTCCTGGTGGGCAGGACCCAGGTCTTACTCTTTTCTGAGTCCTTGGTACCTAG TATAGAACCAAGCACATGTAATTGGGATGGCACATGTAGGTGTGCAAGTTGCCTAATGCA CAATGATACCCACTGAGGTCAAGGAGCAGGTTGAAATCTATCCTACACACTGCTCAAAGC CACCGGCATTGCTCTAAGATGTATCTGGCCAGAGGAAGAGGCATTGTTTCTTTTACACAA AGGACCTGCAGGGTTGCATCCACCTAAGAGGATGTCCCCTTTCTTGTGCAAAGTTGCCAC ATTGTCTGCCCTGTGTACAGTGAGTGCTTAGTCTAGGGAATGAGGGAAACAGGACTCGAG TCAGAGATCTGGACATGACTTTCCCAGAAGGGAGGAGGGCACAGTCTCCCATCCTACCCC ACTGCCCTTGTGGGGAAGCCAGTCCTGCCTCTTGTTCTTTTCTCTAGGTATTAGAGATAT CTTTAAACAAAACATCAGCTGTCGAGTCTCGTTCATCACTCGGACACCTGGGGAGCGGTG AGCAGGAATGGGGCTCTGGCAGGTTGGCCTGGCTGAGCCCCCTGCAGAGAAATGAAGGGA GTAGGACTGGCTGATCAGCCCCTGGTAAAATCAGGCATTTGCCCTTTGAAAGTAGCTCAT GGTAGCACAAACATTCCAGCTGCCTCTCTCACCCTATGCTGCTCGGATGCTTGGCTCTCT CCCTGCTGCTCCAGGCCAGAATCATTCTACAAAACAAATCATGAGATCCTATTAATTCAT TTTGTGCCTTGCCCCCTGCCTGGTACCAGGAGCCACTCCCTACCTCTACCCCATGCTCTG CCCAGGGAGTTGTTCTCCTGGCTGCAAAGACAAGGGGAGAACAGCCCCATTTCTTTTTCT CAGCTCCCACCCCCAGGGACTGGGGCCCCCTGCCCCAGAAGCCCCAGAGCTGGGAGGCCC TGGACTGAAGAAGAGGTTTGGCAAAAAGTGAGTGTCTCCCAAATCCCTGGGCCCAAAGAG ACATGGAGAGAAGTCTTAGGGTCCCTAGGCCCCACCCACATATCCTTGACATATAAGCGA CCATCCTGAGTCTCATTCCATTTGTTCCTGACCTGACTGAGAGGTTACAGTGTTGAATGA CTTTTCATCCTCTTCCAGCCTCTGCACCCCATTCTTCAGGCAAGGGTCCTGGCTCAACAG GATGATAGTAAGGGGTCTCCTGGCTCCTGCCTGCTTTGGGCACAGCCTTGAGGCCTGTGC TGGGATCAGGAAGAAAGAAGGATAAAACAGACAGGAGGAGGGGGAGTAGCAGGGAGACAG TGAGTGGGTGGATGGAGCAAAGACAGAAGTAAAGGGTTGGAGGAGGAAGAAGCCCCCAGA TTGCTTTTTTCCATTCATCTGTTGTGGCCCATCCTGATGCCTGCCAGATCCCCAGGTCAC CTTTCATGGAGTGGCATTAAGGGAAGGCCAGAGGGCCCTTACCACACTGCTGCCCTGCCT CCCCTTGCTATAGGGCAGCAGTGCCCACTCCCCGGCTGTACACAGAGGCGCTGCAAGAGA AGATGCAGCGAGGCTTCCTAGCCCAAAAGCTGCAGCAGTACAAGCGCTTCGTGGAGAACT ACCGGAGGCACATCGTGTGTGTGGCAATCTTCTCGGCCATCTGTGTTGGCGTGTTTGCAG ATCGTGCTTACTGTAAGAGTTCCAGGCTGTGGGCAGTGGGTAGGGAGCAGGCTCTGACCC TTGGAGAGGAGTGGAAAGCCCTCTGATCCTAAGAGTCTGCATGGGAGAGCCCAGGGCTCG GGACCTTGGCCACCTGTGCCAAGCTGATGTAACCTCACTCCGGCCCCAGACTATGGCTTT GCCTCGCCACCCTCGGACATTGCACAGACCACCCTCGTGGGCATCATCCTGTCACGAGGC ACGGCGGCCAGCGTCTCCTTCATGTTCTCTTATATCTTGCTCACCATGTGCCGCAACCTC ATAACCTTCCTGCGAGAGACTTTCCTCAACCGCTATGTGCCTTTTGATGCCGCAGTGGAC TTCCACCGCTGGATCGCCATGGCTGCTGTTGTCCTGGCCAGTACGTGACTCCCAGGCTTC TTCCTCTTTGCTGCAGCACCCTGGGTCTAGTTGGGGGAAACAGTGGGGAGATGGAACTCC TTATACCTCCATCTCTCCTCCCTATGCCTCCTCTCTCCCTCAGGATCGGAGGTAGAGTCT GTCCTGGTTGGCATCTCTAACAGGGTCTGTCTCTTCCAGTTTTGCACAGTGCTGGCCACG CAGTCAATGTCTACATCTTCTCAGTCAGCCCACTCAGCCTGCTGGCCTGCATATTCCCCA ACGTCTTTGTGAATGATGGGTCAGTTCTGGGGATGGTTTCTCCTGGGACTCATAGGGTGG GCCCAAGGGTATAATAGAAAAAGAAATAGGCAGGCCGGGCGCGGTGGCTCACGCCTGTAA TCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCAGGAGATCGAGACCATCC TGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTGGTG GTGGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCATGAACCCAA GAGGCGGAGCTTGCAGTGAGCCGGGATAGCGCCACTGCAGTCCAGCTTGGGCGAAAGAGT GAGACTCCGTCTCAAAAAAAAAAAAAAAGAAAGAAATAGGCAGGGCACAATGGCTCACAC CTGTAAGCCCAACACTTTGGAAGTCTGAGGCAGGAGGATTGCTTGAGGCCAGGAGTTCCA GACAAGCCTGAACAACAAAGTGAGACTCCATCTGTACAAAAAGTAAAAAGATTAGCGGGG CATTGTGGTACACATCTGTAGTCCCAGCTATTCAGGAGGCTGAGGCAGGAGGATTGCTTG AGCCCAGGAGTTTTAGGTTGCAGTGAGCCATGATCAGTACCACTGCATTCCAGCCTGGGC GACAGAGCAAGACTCTGTCTTGAAAAAAAAAAAAAGGAAAGAAATAGACAGTCCCAGACA CTCAGCAAGAAGCTCAGTGCTAAGCTAGTCCCCTGGGGGAAGCTGAAAGGTAAATTTCTT GCCTTCAAGAAGGAAGCTGGCTGTGATTGGCCAGGAAAGGTGTTTGGGAGATGAAGTCAG AGACTCTTTCTCATAGATACCTGACACACAGCTTGCCATCTCTGCCTTCTATCCATTCAC TGGACAGACATTTATGCAGCATGTCCCATGTGTCTACCCAGATGCCAGAGTAGGGATGTC AAGATACATGCAGTCATTCAACAACTACTTACCGAGATTTGCTGTGTGCCTTGTATTGTT CTAAGCCTAGGGATAGAGCAGTGAATGAAACAAAAATCCCTGCCCTCATGGAGCTTACAG AATAATGAACCAGGGACTCAAGGAAGCAGGGGTCAACCACAGTAAGAGAGTTCAGGATAA CACAGAAGGAAAAATTGCTGAGTACAGAGGGTGGAACCATGGAAGCCTGGGTGCCAAGTT CCTTGGAGGGATCCCTGGCCAACTGGGTGGAGGCCCCATACCCTCAGCAGTCAGGGCCAG CAGGAAAGGAGTCATGCTGTGTTGTGACAGTGCTGGAGCCCCTCCTGCCCCAGTCAGAGG CTCAAGGTGCCTTTGCCCCCCAGGTCCAAGCTTCCCCAGAAGTTCTATTGGTGGTTCTTC CAGACCGTCCCAGGTAGGAAACGTGGGACCTGGGGGTTCTGTCTGAGGACTTCTGCTTTT GTCTCCATCTCTCTGTGAATACTCACTTGTCTATACTGGCCATGGGGTCTGTTTCTAGCC TTCAGGACAAGCCCCAGCTCAAATCCCTCCAGGCAGGCTTTTCTGGGGGCCCCGGAGGGA TGAGAGAGGAAGGAGGGAAGGATAGGGGAATGTGCTGTTGTCTTTTCAGCCCAAGCTGAA GTCCTGAGACTACTCACTGGCCCTGTCTTCCTGCCCCCAGGTATGACAGGTGTGCTTCTG CTCCTGGTCCTGGCCATCATGTATGTCTTCGCCTCCCACCACTTCCGCCGCCGCAGCTTC CGGGGCTTCTGGCTGACCCACCACCTCTACATCCTGCTCTATGCCCTGGTGAGGGACTTC CCTGGGCCAGCCCATGGAGCAGGGAGCTCAGGATGGGACAGGAAGGTGAAAGAGGGAGAA TTGGATCCAAGATCTCAGAATGAGACTTTGAGATTTAAGACCCCAGACCTCAGCCCTATC TCCCCGGCACAGGCCTAGTGCCTGGGCAAGAGGGGATGCCGGGCAGGGGCCTGGCTGGGC CTGAGTTGTACTAACTGGCCGTGTCTCCAGCTCATCATCCATGGCAGCTATGCTCTGATC CAGCTGCCCACTTTCCACATCTACTTCCTGGTCCCGGCAATCATCTATGGAGGTGACAAG CTGGTGAGCCTGAGCCGGAAGAAGGTGGAGATCAGCGTGGTGAAGGCGGAGCTGCTGCCC TCAGGTATCAGGCCCAGCCTGACCTGGGTCGGGAGCGACAGAGGCCAAATCTTCAGACAT GGGGAGACAGTTCACCAGGTCTCCTGACCCCATCACTGCCTCTGACTCTGTCTCCAAAAA CAACAACAACAAAAAACCACTCTCGGGGGTTCCTGAAGGTTTCCTGATAGAAGTAGACCC AGAAAGGGCTGTGCTTAGCTCCCAGGAGACTTGCAGATGGTGAGAAGTGACCTGAGAAGA GGTGGCTGAACGTGCATACAGAGGGGTTTGAGGATGGGAAAGGGCCCCACATGTGTGGCC TGGGTGCAGGGGAAGTGCAGGGCAGGAAGCCACATATGCCTGTCCCATTCCTTCTCTCAG AGACAGGCAAATGCCCAGATTGCCAGTCTGGGTTGTTGAGAGTCAGTGCTGGCCAAAGTC GGGATTGGTATCATCATAGAGGGTGGCAAAAGATGATTTTATGTATCTCAGGACTGTCTA ACCTTCAGGACTCATGTTGTAAAAAAATTAATCTCATTGCAATGTTATTTCAATTGAGAT TACTTAAGGACAAAATCTCAGAGTGGTGTTAGTATGCCTTTCTACTCTCCAGCACTTGCT GATCTCCTTTTTCAATGAAGAGATCAGGCCTGAGGCTCAGCTATGGTACAAACAGTATCC AGCTAAAATTTGGTAACAAAATATGTTGTCTTCTATGTAGGACACATGATACTGGTTTTC CACTTACCTTAGCAATAAAGTTCCCTGCCAAGATTAATTGAATTGGAAAAGTTAGTCAAT TTAAAGAAAAGTGTTAGATAAATGATAGTGCAGGAGGTGTGTAGAAAGGTAACCCTCAAA TGGAGGTCTGGTAGCCACTGAGATGGTCCCTGGTGAGCCTGAGTCCCTTTACCCAGCAGG TTGGTATTCAAGGCAGTGGTATGAGGCCTGGGCCTTCCATGGGAAGAGGGAGTAGAGAGG AGGAGAGGGGCTGGAACAGGGGAGCAGAGAAACCCAGCTCTTGCATTACCTGGGAAACAG AGAAGGGGACCCTCCTACTCCCAGCCCCAGGAGCCCCGCTTGCTCAGACCATGTGACTAC TCCCCAGGCCTCAGGGGTGTGAAGAGGACAGGTGCCTATCAGTCCTCAGGTACCAGGAGC AGGCCTTCTCATCTGTGCTTTTCCCTGTCTATGACCTCCAGGAGTGACCTACCTGCAATT CCAGAGGCCCCAAGGCTTTGAGTACAAGTCAGGACAGTGGGTGCGGATCGCCTGCCTGGC TCTGGGGACCACCGAGTACCACCCCTTCACACTGACCTCCGCGCCCCATGAGGACACACT CAGCCTGCACATCCGGGCAGTGGGGCCCTGGACCACTCGCCTCAGGGAGATCTACTCATC CCCAAAGGGCAATGGCTGTGCTGGATACCCAAAGGTGCCCGTCACTGGGAACCCTGCTTC CGGGCCTCTGGCACTGGCAGAGGATCTCTGCCCTTCCCTATCCTGAGACTAGAAGCTCCA GCCGTCCCAAAGCCAGCCTGGGAGAGGACCGGGGTGCCTCAGAAAAGACTAGGATGTTCT GTATCCTCCCTCTGCCTGTGTCTCCGTTTCTGGTCTCAGAGCTGGGGCAGGGTCAGGCTC ATTTCATCTCCCCCCTCTCTTGGCAGCTGTACCTTGATGGACCGTTTGGAGAGGGCCATC AGGAGTGGCATAAATTTGAGGTGTCAGTGTTGGTGGGAGGGGGCATTGGGGTCACCCCCT TTGCCTCCATCCTCAAAGACCTGGTCTTCAAGTCATCCTTGGGCAGCCAAATGCTGTGTA AGAAGGTGAGCATCCCTCCCTCATTCATCAAATGGGGCATAGGTGGCCGAATTGTGACCC GCATCAAGTGGTGGAGCATGAGAGAAAGCTCCTGGCTCCAGGAACTGAGTCTGAAGGGGT CATTCTTACCCAGTGGTTGAGATGCCAAACTTGGAGGGAGGTTGGTGGTATAGCCAGAAG GGCCTCTGCTGGGACCTGTCAGTTGGAAGCCTGGGATCAGGCTGGTGGGTCCTGCCACAG CTTTGGTGTCTGCAGGTGGTCTGGGGCTTCCCAGCCTCTCAGGTGAAGGCACCTGGGATC TAGGGAGGCTGAACTGAGCTGGGTCCTGATCTCCAGCCCTGTGTCCCCAGATCTACTTCA TCTGGGTGACACGGACCCAGCGTCAGTTTGAGTGGCTGGCTGACATCATCCAAGAGGTGG AGGAGAACGACCACCAGGACCTGGTGTCTGTGCACATTTATGTCACCCAGCTGGCTGAGA AGTTCGACCTCAGGACCACCATGCTAGTATGTCAGGGCCCGCCAGGCAGGGCAACTTGGC GGGCAGATGGATTGGCAGCGTAAGGCAGGATGGCCAGGGCAGGTGGGTGGACGGCCAGGC TGAGCTGGCAGGAGGCACAGAGCTGATGGCCTGATCCTCAGCCTCCAGCTCCCTCCCCTC CCCATTCTCTGTCTCTTGGGCTATGTGGGCTGGCTCGGGCTGAGTGCTGGCCCTGACTGT CTTTGGTCTGACCTGCCCCTGTGCCCCCAGTACATCTGCGAGCGGCACTTCCAGAAAGTG CTGAACCGGAGTCTGTTCACGGGCCTGCGCTCCATCACCCACTTTGGCCGTCCCCCCTTC GAGCCCTTCTTCAACTCCCTGCAGGAGGTCCACCCACAGGTCAGTCCCACTCCCTCCCAC CCTGGGACTCTGGCCTTCTCCTGCCAGGACATCCTGGCCCTGAAGCACCCTGCCACTCTG TTCTGAGCAGAGAACTCCACCCGATTGCCTGGCCCCAGGATGAGGTCAGCTGTTAAAGGG GGACTTCCACCCCCTCCACGTTAAGCCTCCTCCTCAAGGCCTGGGCTTGAAGCCTTAGTC ATTCCAGCCAGGCTCAGGAAGCAGCTTTTCCCAAGGAGAGTGAGCACCTTTAGGCTGCAG GCCCCTCTCTCTCTCCAATCTCCTGACAGGTGCGCAAGATCGGGGTGTTCAGCTGCGGCC CTCCAGGAATGACCAAGAATGTAGAGAAGGCCTGTCAGCTCGTCAACAGGCAGGACCGAG CCCACTTCATGCACCACTATGAGAACTTCTGAGCCTGTCCTCCCTGGCTGCTGCTTCCAG TATCCTGCCTTCTCTTCTGTGCACCTAAGTTGCCCAGCCCTGCTGGCAATCTCTCCATCA GAATCCACCTTAGGCCTCAGCTGGAGGGCTGCAGAGCCCCTCCCAATATTGGGAGAATAT TGACCCAGACAATTATACAAATGAGAAAAGGCAGGAGACTATGTTCTACAATTGCAGTGC ATGATGATTATAAGTCCACCTGTTTATCAACGGCACCATTCCTGCAGCCCTCCAGACTTC CTGCCCTTAGCAAGTGCGCAACCAGTCAGGATCTCCCAAAGAAGATAAAGACCACTCCTC ACCCCAGCTCAAGCCATGGCAGGCGTGGCAAGCAAAGTGGGGAGGAGACAGTCCCTGCTT GTGACAAGTGTGGAGGTGAAAAGGTACAATAGTGCTTGTCTCCGATAGCTCCCCACATCT CTAATTGACTTCCACAAAATCGATGCGTTGCTTTGGTATTTGCTTGGACTGACATTTGAG GGAGGAGGAGGCTGGGATCCTCTGGCTGAGAATCTCCTCAGAGCCCAGTGCAGAAGCTGT GATGCTTAGAACCTGGACAGCCCGACTGCCTCAACTCTGTCTCCAGGTCTATTCCCTCCA GCTCCAAAAGGAGCAGCCCTACTTCTACCCCTTCCCGTCCCCAAAGTGTCAGCAACTTTG AGGAGGGCACCAGGAAACAAAGATGCCTCCCCAGCCCTGATATTCTTGATGTCACCAGTG ATACCCACTGCCCTGACCCCTGGGCAGGCCCCTCTCTGCATCTACTGGAGTGGTCCCTGG GCTCTGGGGCTGAAGGATTCCAGCCTCTCTGCCAGATATTCAGTACTCGATCTCAATTCC CCTCTTCCACAAGAGTTGGGTGACCAGCTGTCCTAGTTTGCCCAGGACTCTCCCTGTTTT AGCACTGAAAGTCTCTTGCCCCAGGAAACCCCATCAGTCCCAGGCAGATTGGGACAGCTG GTCACCTTACGCAAGAGCCAGGCTGAAACATCCCCTCCATACTCAGCTCTTTAACTTTTC TTTTCCTTTTTCATCGGGCTCTTTCCTAAAAAGCTGAGCTGTAAAATATTTTACATCGAG GTATAATAAATAATCATGTACATGTTTTACCACCACCCAGGTCAAGACATAGAATGTTTC AACATTTCCATCACCCCAGAAACTCCCCTTGTACCCCCTTCCACTTCGTCTCCCCTAGCT CCTAGAAGCAACCACTGATGTGATTTCTACCAAATCCAGTTTTGGTCCTACTAAATATAC TCTTTTGAGACTGGCCTCTTTTACTCACCATAATGCCTTTGTAATTCATCCATGCTGTTG TGTGTATCAGCAGTTTGTTCCTTTTCATTGCTGAGTAGTATTCTATTGTAGAGATGTACC ACAGTTTGTTTATTCTTCTGTTGATGGACGTTTGGGTTGTTTCTAATTTTGAATGATTAT AAATAAAAATTCTGTGAGTGTTCTTGTA OMIM ID 606759