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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for OLR1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID4973
Official gene symbolOLR1
Full nameoxidized low density lipoprotein (lectin-like) receptor 1
Aliases,CLEC8A,LOX1,LOXIN,SCARE1,SLOX1,
Gene summaryThis gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
LocationChromosome: 12   Locus: 12p13.2-p12.3
Gene position10324790 - 10310899  Map Viewer
Gene orientationminus
Gene size13892 bp
Gene sequence
OMIM ID602601