| Entrez gene ID | | 4973 |
| Official gene symbol | | OLR1 |
| Full name | | oxidized low density lipoprotein (lectin-like) receptor 1 |
| Aliases | | ,CLEC8A,LOX1,LOXIN,SCARE1,SLOX1, |
| Gene summary | | This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants. |
| Location | | Chromosome: 12 Locus: 12p13.2-p12.3 |
| Gene position | | 10324790 - 10310899 Map Viewer |
| Gene orientation | | minus |
| Gene size | | 13892 bp |
| Gene sequence |
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| OMIM ID | | 602601 |